Special Issues

Life runs special issues to create collections of papers on specific topics. The aim is to build a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors who are experts in the subject and oversee the editorial process for papers. Papers published in a Special Issue will be collected together on a dedicated page of the journal website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Eye Manifestations of Systemic Disease
edited by
submission deadline 25 May 2023 | 7 articles | Viewed by 6984
Keywords: age-related macular degeneration; diabetic retinopathy; ocular trauma; retinal detachments; hereditary retinal and macular diseases
(This special issue belongs to the Section Physiology and Pathology)
Application Research of Bioinformatics in Human Diseases
edited by
submission deadline 25 May 2023 | 4 articles | Viewed by 4601
Keywords:   bioinformatics;   statistical genetics;   data analysis;   omics;   cancers; cardiovascular diseases; obesity; neurodegenerative diseases; mental illness
(This special issue belongs to the Section Biochemistry, Biophysics and Computational Biology)
Abiotic Stress Signaling and Responses in Plants
edited by and
submission deadline 26 May 2023 | 21 articles | Viewed by 23543 | Submission Open
Keywords: abiotic stress; drought; salt stress; cold; hot; nutrient starvation  ; toxic metal  ; signaling
(This special issue belongs to the Section Plant Science)
The Role of Small RNAs as Cancer Biomarkers: Biology and Clinical Potential Application submission deadline 26 May 2023 | 2 articles | Viewed by 1988 | Submission Open
Keywords: small RNA; miRNA; cancer; molecular biology; sequencing; transcriptomics
(This special issue belongs to the Section Medical Research)
Research in Medicinal Chemistry
edited by
submission deadline 26 May 2023 | 1 articles | Viewed by 908 | Submission Open
Keywords: azaheterocycles; cancer drug discovery; drug target; anticancer agents; chemotherapy
(This special issue belongs to the Section Pharmaceutical Science)
Metabolic Plasticity in Cancer submission deadline 26 May 2023 | 1 articles | Viewed by 536 | Submission Open
Keywords: metabolic plasticity; cancer stem cells; OXPHOS; glycolysis; lipid metabolism; cancer metabolic reprogramming
(This special issue belongs to the Section Medical Research)
Best Practices in Acute Coronary Syndromes submission deadline 26 May 2023 | 1 articles | Viewed by 489 | Submission Open
Keywords: acute coronary syndromes; inflammation; satherosclerosis; imaging; biomarkers
(This special issue belongs to the Section Medical Research)
Novel Insights into Heart–Lung Interaction and Hemodynamics submission deadline 27 May 2023 | Viewed by 182 | Submission Open
Keywords: cardiovascular physiology; heart– lung interaction; hemodynamic monitoring; microcirculation
(This special issue belongs to the Section Physiology and Pathology)
Screening, Diagnosis and Treatment of Thyroid Cancer submission deadline 28 May 2023 | 1 articles | Viewed by 837 | Submission Open
Keywords: thyroid cancer; Iodine-131 therapy; radiation protection; dosimetry; external beam radiation; MEN2 genetics; surgical management of thyroid; thyroid nodule management; Sestamibi scintigraphy
(This special issue belongs to the Section Medical Research)
Virology Applications to COVID-19 Pandemic submission deadline 30 May 2023 | 14 articles | Viewed by 25245 | Submission Open
Keywords: SARS-CoV-2; COVID-19; Disease burden; Healthcare burden; Public health measures; Prevalence; Incidence; Epidemiology; Clinical aspects; Viral pathogenesis
(This special issue belongs to the Section Epidemiology)
Inflammation and Natural Products submission deadline 30 May 2023 | 7 articles | Viewed by 6837 | Submission Open
Keywords: natural products; inflammation; biological activity; anti-inflammatory activity; antioxidant activity; anticancer potential; terrestrial products; marine products; phytochemistry; pharmacology
(This special issue belongs to the Section Pharmaceutical Science)
Abiotic Stress in Horticultural Plant: Insight into Recent Advances in the Underlaying Tolerance Mechanism submission deadline 30 May 2023 | 1 articles | Viewed by 1043 | Submission Open
Keywords: phytohormones; abiotic stress; antioxidant response; oxidative stress; plant physiology; molecular biology; horticultural plants; food security; tolerance mechanism
(This special issue belongs to the Section Plant Science)
The Role of Autophagy in Cancer submission deadline 30 May 2023 | 1 articles | Viewed by 845 | Submission Open
Keywords: autophagy; cancer; exosomes; cell death; homeostasis; tumor; tumorigenesis; tumor microenvironment
(This special issue belongs to the Section Physiology and Pathology)
Molecular and Cellular Mechanisms Underlying the Microbial Survival Strategies submission deadline 30 May 2023 | Viewed by 205 | Submission Open
Keywords: cyanobacteria; microalgae; biosynthetic pathways; gene-editing; bioengineering; bioprocess; biorefinery; circular economy; multi-omics; photoautotrophic metabolism; stress response
(This special issue belongs to the Section Microbiology)
Advances in Human Genetics and Reproductive Biology
edited by
submission deadline 30 May 2023 | Viewed by 138 | Submission Open
(This special issue belongs to the Section Physiology and Pathology)
Plant Biotic and Abiotic Stresses
edited by and
submission deadline 31 May 2023 | 56 articles | Viewed by 61715 | Submission Open
Keywords: plant abiotic stress tolerance; drought; salinity; cold; heat; submergence; waterlogging; heavy metals stress; climate changes; oxidative stress; lighting damage; plant biotic stress tolerance; bacteria; viruses; fungi; insects
(This special issue belongs to the Section Plant Science)
Plants as a Promising Biofactory for Bioactive Compounds
edited by
submission deadline 31 May 2023 | 16 articles | Viewed by 15924 | Submission Open
Keywords: plant cell culture; plant tissue culture; medicinal plants; secondary metabolites; bioactive compounds; nutraceuticals; recombinant proteins; biologics
(This special issue belongs to the Section Plant Science)
The New Frontier of Venous Thromboembolism submission deadline 31 May 2023 | 8 articles | Viewed by 11927 | Submission Open
Keywords: venous thromboembolism; treatment; prophylaxis; biomarkers; antithrombotic drugs
(This special issue belongs to the Section Medical Research)
Food and Environmental Toxicology submission deadline 31 May 2023 | 7 articles | Viewed by 6193 | Submission Open
Keywords: food toxicology; risk assessment; environmental pollution; toxic risk; toxic metals; trace elements; fluoride; nitrates; marine pollution; novel foods
(This special issue belongs to the Section Epidemiology)
Obstructive Sleep Apnea: Current Knowledge and Future Perspectives submission deadline 31 May 2023 | 6 articles | Viewed by 5935 | Submission Open
Keywords: sleep apnoea syndrome— clinical and pathophysiological phenotypes; diagnosis and comorbidities; biomarkers; personalized treatment; predictors of outcomes; prognosis and mortality
(This special issue belongs to the Section Physiology and Pathology)
Artificial Intelligence Applications for Imaging in Life Sciences submission deadline 31 May 2023 | 5 articles | Viewed by 5334 | Submission Open
Keywords: imaging in life sciences; machine learning; deep learning; computer vision; image segmentation; classification
(This special issue belongs to the Section Radiobiology and Nuclear Medicine)
COVID-19 Prevention and Treatment: 2nd Edition submission deadline 31 May 2023 | 6 articles | Viewed by 4215 | Submission Open
Keywords: COVID-19; SARS-CoV-2; therapies; drug repurposing; tailored treatment; personalized medicine
(This special issue belongs to the Section Epidemiology)
Natural Products on Health and Diseases submission deadline 31 May 2023 | 3 articles | Viewed by 3720 | Submission Open
Keywords: natural products; bioactive compounds; antioxidant; anti-inflammatory; obesity; hypertension; diabetes; cancer; aging; dyslipidemia; Alzheimer's; Parkinson’ s; depression
(This special issue belongs to the Section Plant Science)
Current Research on Optic Nerve Ultrasound Evaluation
edited by
submission deadline 31 May 2023 | 2 articles | Viewed by 3009 | Submission Open
Keywords: ocular ultrasonography; optic nerve; optic nerve sheath diameter; ONSD; ultrasound
(This special issue belongs to the Section Radiobiology and Nuclear Medicine)
The Interplay between Immune System and the Kidneys: Games without Frontiers? : 2nd Edition submission deadline 31 May 2023 | 3 articles | Viewed by 2932 | Submission Open
Keywords: adaptive immunity; autoimmune diseases; chronic kidney disease; glomerulonephritis; systemic diseases and the kidney; vasculitis; immunosuppression; renal transplantation
(This special issue belongs to the Section Medical Research)
Surgical Treatment and Outcomes of Lung Cancer
edited by
submission deadline 31 May 2023 | 3 articles | Viewed by 2736 | Submission Open
Keywords: NSCLC; SCLC; surgery; induction therapy; radiation therapy; EBUS; robotic; VATS; locally advanced NSCLC; immunotherapy; target therapy
(This special issue belongs to the Section Medical Research)
Drug-Like Small Molecule Inhibitors of Viral Targets
edited by and
submission deadline 31 May 2023 | 2 articles | Viewed by 1929 | Submission Open
Keywords: emerging viruses; small-molecule inhibitors; antiviral; drug likeness; viral targets; drug discovery; ADME; PK; toxicity; drug combination; drug repurposing
(This special issue belongs to the Section Pharmaceutical Science)
Developing Artificial Intelligence for Cancer Diagnosis and Prognosis
edited by , and
submission deadline 31 May 2023 | 2 articles | Viewed by 1914 | Submission Open
Keywords: deep learning/machine learning/deep neural network; cancer diagnosis; prognosis prediction
(This special issue belongs to the Section Medical Research)
Mitochondrial DNA Genetic Diversity submission deadline 31 May 2023 | 2 articles | Viewed by 1863 | Submission Open
Keywords: mitochondrial DNA; population genetics; biodiversity; genotype to phenotype; production traits; sport performances; animal health
(This special issue belongs to the Section Genetics and Genomics)
Drug Discovery and Drug Design
edited by
submission deadline 31 May 2023 | 2 articles | Viewed by 1507 | Submission Open
Keywords: drug discovery; drug design; translational drug discovery; reverse translation; network pharmacology; drug repurposing
(This special issue belongs to the Section Pharmaceutical Science)
Recent Advances in Drug and Medical Device Formulations Used for Improving the Quality of Life submission deadline 31 May 2023 | 1 articles | Viewed by 1381 | Submission Open
Keywords: life quality; health/disease; functional foods; bioactive molecules; medicinal chemistry; plant/lichen secondary metabolites; phytochemicals; pharmacological potential; antioxidants/pro-oxidants; antimicrobial activity; antiviral agents; protease inhibitors; cytotoxicity; cell signaling; medicinal plants; phytotherapy; drug discovery; drug delivery; pharmaceutical formulation; medical devices
(This special issue belongs to the Section Physiology and Pathology)
Glomerular Diseases
edited by Sophia Lionaki and
submission deadline 31 May 2023 | 3 articles | Viewed by 1250 | Submission Open
Keywords: glomerular disease; pathogenesis; management; outcome
(This special issue belongs to the Section Medical Research)
HIV and STIs Prevention submission deadline 31 May 2023 | 2 articles | Viewed by 1176 | Submission Open
Keywords: HIV; PREP; PEP; DoxyPREP; treatment as prevention; U=U; STIs; awareness campaign; vulnerable populations; screening
(This special issue belongs to the Section Microbiology)
New Advance in Neuroimaging for Clinical Neuropsychiatric Diseases submission deadline 31 May 2023 | 1 articles | Viewed by 934 | Submission Open
Keywords: neuroimaging; brain activity; neuropsychiatric disorders; connectivity; noninvasive stimulation; AI deep learning
(This special issue belongs to the Section Radiobiology and Nuclear Medicine)
Post COVID-19 Immunological Era submission deadline 31 May 2023 | 1 articles | Viewed by 823 | Submission Open
Keywords: COVID-19; immune response; immune therapies and COVID-19; COVID-19 and inflammatory diseases; COVID-19 and immune-mediated disorders; post-COVID-19 infection and immunology
(This special issue belongs to the Section Physiology and Pathology)
Early Career Researchers in Origins of Life
edited by and
submission deadline 31 May 2023 | Viewed by 565 | Submission Open
Keywords: origins of life; astrobiology; prebiotic chemistry; chemical evolution
(This special issue belongs to the Section Origin of Life)
Emerging and Re-emerging Zoonotic Infectious Diseases submission deadline 31 May 2023 | Viewed by 277 | Submission Open
Keywords: zoonoses; emerging and re-emerging infectious diseases; immunopathogenesis; molecular epidemiology; clinical manifestation of infectious diseases; chronic sequelae of infectious diseases; epidemic/pandemic potential of zoonotic infectious diseases; vaccines and therapeutics; preparedness; biosafety; biosecurity
(This special issue belongs to the Section Microbiology)
Application of Proteomics in Metabolic Diseases
edited by , and Alok Kumar
submission deadline 31 May 2023 | Viewed by 219 | Submission Open
Keywords: proteomics; metabolic diseases; metabolites; diabetes; heart disease; cancer
(This special issue belongs to the Section Proteins and Proteomics)
New Insights in Zika Virus Pathogenicity and Resistance to Infection submission deadline 31 May 2023 | Viewed by 177 | Submission Open
Keywords: zika virus; arbovirus; flavivirus; ZIKV pathogenicity; ZIKV resistance; microcephaly; maternal health; child health; Guillain– Barre syndrome
(This special issue belongs to the Section Microbiology)
Study of Mitochondrial Dysfunction Using Genome and Transcriptome Analysis submission deadline 31 May 2023 | Viewed by 151 | Submission Open
Keywords: mitochondrial dysfunction; cellular dysfunction; human diseases; mutation; gene; mitochondrial genome; transcriptome
(This special issue belongs to the Section Physiology and Pathology)
Peripheral Nerves in Health and Disease: Imaging, Basic and Clinical Research submission deadline 31 May 2023 | Viewed by 146 | Submission Open
Keywords: peripheral nerve; imaging; neuropathy; anatomy
(This special issue belongs to the Section Medical Research)
Next Generation Sequencing: Applications for Cardiovascular Disease
edited by
submission deadline 31 May 2023 | Viewed by 127 | Submission Open
Keywords: next-generation sequencing; cardiovascular diseases
(This special issue belongs to the Section Biochemistry, Biophysics and Computational Biology)
Update on Mechanisms Underlying Chronic Pain
edited by
submission deadline 31 May 2023 | Viewed by 104 | Submission Open
Keywords: chronic pain; neurophysiology; psychophysiology; behavior; hyperalgesia; allodynia; peripheral sensitization; central sensitization
(This special issue belongs to the Section Physiology and Pathology)
COVID-19 and Long-COVID-19: Pathogenesis, Clinical Manifestation, and Therapeutic Options: 2nd Edition
edited by and Alessandro Santo Bortone
submission deadline 1 Jun 2023 | 3 articles | Viewed by 2850 | Submission Open
(This special issue belongs to the Section Physiology and Pathology)
Dynamics of Chromosome Evolution across Animals and Plants: Advances, Insights, and Prospects submission deadline 1 Jun 2023 | 1 articles | Viewed by 631 | Submission Open
Keywords: chromosomal rearrangements; synteny; chromosome evolution; karyotype organization; speciation; species’ diversification
(This special issue belongs to the Section Genetics and Genomics)
Population Genetic Changes under Environmental Stress: Updated State of the Art
edited by Marina Stamenković-Radak and Dragana D. Cvetković
submission deadline 1 Jun 2023 | Viewed by 133 | Submission Open
Keywords: environmental stress; population genomics; epigenetics; adaptation; stress response; gene-by-environment interactions
(This special issue belongs to the Section Evolutionary Biology)
Neurotrophic Factors: Their Roles in Disease and Therapeutics
edited by
submission deadline 2 Jun 2023 | Viewed by 98 | Submission Open
Keywords: ciliary neurotrophic factor; glial derived neurotrophin factor; leukemia inhibitor factor; insulin like growth factor 1; neurotrophin 3; neurotrophin 4; pleiotrophin
(This special issue belongs to the Section Pharmaceutical Science)
Immunity in Viral or Bacterial Infections
edited by , and
submission deadline 6 Jun 2023 | 4 articles | Viewed by 4263 | Submission Open
Keywords: acquired immunity; innate immunity; viral infection; bacterial infection
(This special issue belongs to the Section Physiology and Pathology)
New Insights into Non-Hodgkin’s B-lymphomas: The Evolving Landscape in the Next-Generation Target Therapy Era submission deadline 6 Jun 2023 | Viewed by 133 | Submission Open
Keywords:   non-Hodgkin’ s lymphoma;   target therapy;   immunotherapy;   monoclonal antibodies;   CAR-T cells
(This special issue belongs to the Section Medical Research)
Immunology in Sexual Reproductive Biology and Medicine submission deadline 9 Jun 2023 | 1 articles | Viewed by 1147 | Submission Open
Keywords: in vitro fertilization; genetics in animal breeding; artificial insemination; reproductive efficiency; immunoinfertility; miscarriage; repeated implantation failure; recurrent pregnancy loss; immunocontraception; pregnancy complications; reproductive tract mucosal immunology; fetal tolerance; blood-placental barrier; wildlife reproduction
(This special issue belongs to the Section Reproductive and Developmental Biology)
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