Special Issues

Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Mechanisms of Immune Responses and Complications in Transplantation
edited by
submission deadline 31 Jul 2024 | Viewed by 191 | Submission Open
Keywords: organ transplantation; transplant immunology; organ damage and repair; transplant-related diseases; clinical treatment; molecular mechanism; immune responses
(This special issue belongs to the Section Medical Research)
Robot-Assisted Surgery: New Trends and Solutions
edited by and Felipe Boff Maegawa
submission deadline 31 Jul 2024 | Viewed by 150 | Submission Open
Keywords: robotic surgery; minimally invasive abdominal surgery; minimally invasive liver surgery; minimally invasive pancreatic surgery
(This special issue belongs to the Section Medical Research)
Pediatric Allergic and Immunological Diseases
edited by Cristiana Indolfi and
submission deadline 31 Jul 2024 | Viewed by 144 | Submission Open
Keywords: allergy; children; atopy; asthma; atopic dermatitis; food allergy; allergic rhinitis; treatment; prevention
(This special issue belongs to the Section Physiology and Pathology)
Diagnostic Imaging in Colorectal Cancer
edited by and Chiara Zanon
submission deadline 31 Jul 2024 | Viewed by 107 | Submission Open
Keywords: colorectal cancer; artificial intelligence; texture analysis; ultrasound; magnetic resonance imaging; PET/MRI
(This special issue belongs to the Section Radiobiology and Nuclear Medicine)
Mechanisms and New Aspects in the Treatment of Atrial Fibrillation
edited by
submission deadline 31 Jul 2024 | Viewed by 99 | Submission Open
Keywords: atrial fibrillation; ion channel; electrical remodeling; structural remodeling; arrhythmia
(This special issue belongs to the Section Physiology and Pathology)
The Role of Mitochondria in Cardio-Immunology in Response to Stress Heart Conditions
edited by and Xiawei Dang
submission deadline 31 Jul 2024 | Viewed by 91 | Submission Open
Keywords: mitochondria metabolism; myocardial infraction; cardiac repair; immune cardiac metabolism; mitochondria macrophages
(This special issue belongs to the Section Physiology and Pathology)
Gynecological Endocrinology: From Physiological Mechanisms to Clinical Practice
edited by Ralitsa Robeva
submission deadline 31 Jul 2024 | Viewed by 83 | Submission Open
Keywords: PCOS; hypothalamic amenorrhea; congenital adrenal hyperplasia; hypogonadotropic hypogonadism; premature ovarian insufficiency (POI)
(This special issue belongs to the Section Physiology and Pathology)
New Advancements in Cardiac Imaging
edited by Filippo Toriello
submission deadline 31 Jul 2024 | Viewed by 79 | Submission Open
Keywords: cardiovascular diseases; cardiovascular imaging; artificial intelligence; echocardiography; cardiac magnetic resonance imaging; computed tomography; diagnostic strategies
(This special issue belongs to the Section Radiobiology and Nuclear Medicine)
What Is Life?
edited by and André Brack
submission deadline 9 Aug 2024 | 7 articles | Viewed by 9842 | Submission Open
Keywords: definition of life; origins of life; synthetic biology; theoretical biology; quantum biology; water; time; electrostatic potential; DNA; mutations; molecular interactions
Revolutionizing Drug Delivery: Innovations in Targeted Therapeutic Nanocarriers
edited by Vanessa F.C. Dartora
submission deadline 15 Aug 2024 | 6 articles | Viewed by 9658 | Submission Open
Keywords: target therapy; biomaterials; nanomedicine; pharmaceutical; nanocarriers; drug loading and release; characterization; regulatory; biocompatibility; therapeutic nanocarriers
(This special issue belongs to the Section Pharmaceutical Science)
The Role of Microorganism in the Etiopathogenesis of Demyelinating Diseases
edited by
submission deadline 20 Aug 2024 | 2 articles | Viewed by 3476 | Submission Open
Keywords: multiple sclerosis; NMOSD; MOGAD; experimental autoimmune encephalomyelitis (EAE); infection; neuroinflammation; demyelination
(This special issue belongs to the Section Microbiology)
Pathophysiology, Diagnosis and Treatment of Immune Disease
edited by and Lucia Vietri
submission deadline 20 Aug 2024 | 1 articles | Viewed by 1154 | Submission Open
Keywords: immune disease treatment; autoimmunity; biomarkers; treatment; immunology
(This special issue belongs to the Section Physiology and Pathology)
Innovative Technologies in Neurosurgery and Neuroanatomy
edited by , , Santino Ottavio Tomasi and
submission deadline 20 Aug 2024 | Viewed by 189 | Submission Open
Keywords: neurosurgery; innovative technologies; robotic surgery; augmented reality; mixed reality; virtual reality; surgical education; surgical planning; intraoperative navigation; imaging tools; theranostics; brain malignancies; spine malignancies; neuroanatomy; original articles; reviews; technical notes
(This special issue belongs to the Section Medical Research)
Effects of Exercise Training on Muscle Function
edited by Marco Duca and
submission deadline 26 Aug 2024 | 3 articles | Viewed by 2738 | Submission Open
Keywords: exercise; training; muscle function; resistance training; HIIT
(This special issue belongs to the Section Physiology and Pathology)
Study on Placenta and Pregnancy Screening
edited by
submission deadline 27 Aug 2024 | Viewed by 134 | Submission Open
Keywords: perinatal ultrasound; serum markers for complications of pregnancy; histopathology of the placenta; neonatal pathological conditions; sonographic parameters; molecular markers; extravillous and villous trophoblasts
(This special issue belongs to the Section Physiology and Pathology)
Stem Cell Transplantation in Hematologic Malignancies
edited by
submission deadline 27 Aug 2024 | Viewed by 62 | Submission Open
Keywords: hemopoietic stem cell; transplantation; autologous; allogeneic; haploidentical; graft versus tumor; graft versus host; consolidation therapy; maintenance therapy
(This special issue belongs to the Section Physiology and Pathology)
Multi-disciplinary Approaches against Female Diseases
edited by
submission deadline 30 Aug 2024 | 7 articles | Viewed by 8556 | Submission Open
Keywords: female cancers; female related diseases; clinical approach; basic scientific approach; interdisciplinary approach; diagnosis; therapy; prevention
(This special issue belongs to the Section Physiology and Pathology)
New Insights in Skin Oncology: From Pathogenesis to Treatment submission deadline 30 Aug 2024 | 2 articles | Viewed by 3922 | Submission Open
Keywords: non-melanoma skin cancer; melanoma; lymphoma; cutaneous oncology; paraneoplastic
(This special issue belongs to the Section Physiology and Pathology)
Recent Advances in Chemosensory-Based Behaviorally, Physiologically, and Molecularly Manipulated Technology of Pest Insects
edited by and Nanji Jiang
submission deadline 30 Aug 2024 | 4 articles | Viewed by 3865 | Submission Open
Keywords: insect pests; chemosensory reception; environmental cues; neural pathways; molecular function; pest management
(This special issue belongs to the Section Animal Science)
Vascular Disease: Etiologic, Diagnostic, Prognostic and Therapeutic Research—2nd Edition submission deadline 30 Aug 2024 | 4 articles | Viewed by 2912 | Submission Open
Keywords: vascular diseases; etiology; diagnosis; prognosis; therapy
(This special issue belongs to the Section Medical Research)
Applications of EEG in Neural Rehabilitation: 2nd Edition submission deadline 30 Aug 2024 | 2 articles | Viewed by 2610 | Submission Open
Keywords: neurorehabilitation; neuroplasticity; EEG; ERPs; qEEG; EEG mediated patient-therapist interaction; BCI; exoskeleton; cognitive rehabilitation; brain rewiring
(This special issue belongs to the Section Radiobiology and Nuclear Medicine)
Neuronal and Behavioral Changes as a Response to Biotic and Abiotic Factors submission deadline 30 Aug 2024 | 1 articles | Viewed by 2475 | Submission Open
Keywords: nervous system; behavior; biotic factors; abiotic factors; natural/synthetic compounds; laboratory and field work
(This special issue belongs to the Section Physiology and Pathology)
Circadian Rhythms Regulation in Aquatic Animals
edited by
submission deadline 30 Aug 2024 | 1 articles | Viewed by 1232 | Submission Open
Keywords: circadian rhythms; aquatic animals; biological clocks; entrainment mechanisms; molecular clockwork; environmental cues; circadian dysregulation; physiology; behavior; ecology
(This special issue belongs to the Section Animal Science)
Neuropathogenesis of Chronic Toxoplasma gondii Infection in Immunocompetant Hosts
edited by and Robert H. Yolken
submission deadline 30 Aug 2024 | 1 articles | Viewed by 1104 | Submission Open
Keywords: bradyzoites; cysts; chronic infection; neuroinflammation; neuropsychiatric disease; parasite persistence; bradyzoite recrudescence; schizophrenia
(This special issue belongs to the Section Microbiology)
Recent Advances in Shockwave Therapy for Musculoskeletal and Soft-Tissue Disorders
edited by , , Maria Chiara Vulpiani, Maria Cristina D'Agostino, Larisa Ryskalin and Federica Fulceri
submission deadline 30 Aug 2024 | 1 articles | Viewed by 429 | Submission Open
Keywords: shockwave; tissue regeneration; pain; functional recovery and healing; physical medicine and rehabilitation; clinical applications; imaging
(This special issue belongs to the Section Medical Research)
Strategies for Controlling Synthetic Cells: Approaches, Models, Applications
edited by and
submission deadline 30 Aug 2024 | Viewed by 304 | Submission Open
Keywords: artificial cells; bioreactors; biosensor; cell-free systems; coacervates; controlled behavior; DNA signals; drug delivery; gene expression regulation; liposomes; microcompartments; modeling; molecular communication; nanomedicine; nanoparticles; optogenetics; polymersomes; protocells; signaling; stimulus-response; synthetic biology; synthetic cells
(This special issue belongs to the Section Synthetic Biology and Systems Biology)
Clinical and Epidemiological Findings on Pediatric Rheumatism
edited by Lampros Fotis
submission deadline 30 Aug 2024 | Viewed by 136 | Submission Open
Keywords: pediatric rheumatology; clinical presentations; epidemiology; disease-modifying therapies; long-term outcomes; treatment approaches; autoimmune disorders; inflammatory conditions; juvenile idiopathic arthritis; systemic lupus erythematosus; juvenile dermatomyositis; childhood rheumatic diseases
(This special issue belongs to the Section Epidemiology)
Alterations of the Metabolic Homeostasis in Aging
edited by
submission deadline 30 Aug 2024 | Viewed by 115 | Submission Open
Keywords: aging; cardiovascular impairment; neurodegenerative disease; cancer; metabolic homeostasis; inflammatory response
(This special issue belongs to the Section Physiology and Pathology)
The Regulation Networks of the Circadian Clock in Plants
edited by
submission deadline 30 Aug 2024 | Viewed by 94 | Submission Open
Keywords: plant circadian; circadian clock; transcriptional; post-transcriptional; epigenetic mechanisms
(This special issue belongs to the Section Plant Science)
Updates in Cardiovascular Medicine: Diagnosis, Treatment and Technical Aspects: 2nd Edition submission deadline 31 Aug 2024 | 1 articles | Viewed by 855 | Submission Open
Keywords: cardiology; cardiovascular medicine; interventional cardiology
(This special issue belongs to the Section Physiology and Pathology)
Environmental Exposure and Human Health: Morphological, Physiological and Clinical Consequences
edited by
submission deadline 31 Aug 2024 | 1 articles | Viewed by 810 | Submission Open
Keywords: environmental risk; human health; morphological studies; physiological studies; molecular aspects; clinical implications; biomarkers; advanced imaging techniques; risk factors; mechanistic studies
(This special issue belongs to the Section Physiology and Pathology)
Clinical Management and Prevention of Adverse Pregnancy Outcomes submission deadline 31 Aug 2024 | Viewed by 108 | Submission Open
Keywords: pathologic pregnancies; ultrasound; clinical and molecular characteristics; fetal pathologies
(This special issue belongs to the Section Reproductive and Developmental Biology)
Ecotoxicity Effects of Metals and Microplastics on Aquatic Organisms
edited by Chiara Martino
submission deadline 31 Aug 2024 | Viewed by 82 | Submission Open
Keywords: aquatic organisms; emerging contaminants; metals; microplastics; defense strategies; cell stress; heavy metals; environmental stress; pollution; ecotoxicology
(This special issue belongs to the Section Animal Science)
Management of Ischemia and Heart Failure—2nd Edition
edited by
submission deadline 31 Aug 2024 | Viewed by 79 | Submission Open
Keywords: cardiac ischemia; heart failure; therapy; medical innovation; emerging technologies; care strategies; prognosis; treatment efficacy; clinical protocols; personalized therapies
(This special issue belongs to the Section Medical Research)
Stem Cell and Developmental Biology: At the Interface of Differentiation and Morphogenesis
edited by and Kristen Panfilio
submission deadline 2 Sep 2024 | Viewed by 241 | Submission Open
Keywords: stem cell biology and tissue aging  ; gene regulatory networks and epigenetics  ; signalling and cell– cell interactions; differentiation and morphogenesis  ; tissue mechanics and mechanotransduction; germ cells and reproduction; evolution of developmental control
(This special issue belongs to the Section Cell Biology and Tissue Engineering)
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) submission deadline 10 Sep 2024 | 2 articles | Viewed by 3938 | Submission Open
Keywords: PRRS; pathogenesis; immune; prevention; vaccines; vaccinology; pig
(This special issue belongs to the Section Microbiology)
Early Diagnosis and Management of Gynecological Malignancies
edited by Vasileios Pergialiotis
submission deadline 15 Sep 2024 | Viewed by 71 | Submission Open
Keywords: ovarian cancer; cervical cancer; uterine cancer; vulvar cancer; early diagnosis; morbidity and mortality; prognosis
(This special issue belongs to the Section Medical Research)
Freeze-Dried Plasma for Major Trauma: Trends and Applications submission deadline 20 Sep 2024 | 1 articles | Viewed by 1283 | Submission Open
Keywords: blood products; blood transfusion; coagulation; freeze-dried plasma; fresh frozen plasma; hemorrhage; hemorrhagic shock; hemostatic agent; hemostatic resuscitation; major trauma; massive transfusion; prehospital resuscitation; trauma coagulopathy
(This special issue belongs to the Section Medical Research)
Emerging Biomarkers: Recent Findings and Application in Pathological Condition Detection—2nd Edition submission deadline 27 Sep 2024 | Viewed by 106 | Submission Open
Keywords: biomarkers; biological fluids; early diagnosis; laboratory medicine
(This special issue belongs to the Section Medical Research)
Research Update in Pregnancy Complications submission deadline 30 Sep 2024 | 6 articles | Viewed by 8059 | Submission Open
Keywords: general condition; pregnancy complication; ocular anomaly; neuro-ophthalmological disease; ocular malformations  ; fetal abnormality; infection disease  ; diabetes mellitus; preeclampsia; prenatal diagnosis; genetic testing; amniocentesis
(This special issue belongs to the Section Reproductive and Developmental Biology)
Human Health before, during, and after COVID-19
edited by Alessia Verduri
submission deadline 30 Sep 2024 | 4 articles | Viewed by 4447 | Submission Open
Keywords: COVID-19; telemedicine; pandemic-related anxiety; pandemic-related depression; long COVID; unvaccinated people; new SARS-CoV-2 variants
(This special issue belongs to the Section Epidemiology)
Extremophiles Breakthrough: Hot Topics and Current Issues in Their Isolation, Identification and Biotechnological Applications submission deadline 30 Sep 2024 | 3 articles | Viewed by 4299 | Submission Open
Keywords: astrobiology; biochemistry and molecular biology; biodiversity and ecology; biotechnology; extraterrestrial analogs; extreme environments; extremophiles; genetics; genomics; and proteomics; origin of life; phylogeny and evolution; physiology and metabolism
(This special issue belongs to the Section Microbiology)
The Brain Barriers: Functions and Implications submission deadline 30 Sep 2024 | 2 articles | Viewed by 3182 | Submission Open
Keywords: brain barriers; brain homeostasis; neurodegeneration; neuroinflammation; brain drug delivery
(This special issue belongs to the Section Physiology and Pathology)
New Insights into Allergic Eye Diseases submission deadline 30 Sep 2024 | 2 articles | Viewed by 2711 | Submission Open
Keywords: allergy; IgE; IL-4; IL-5; IL-13; TNF-alpha; mast cells; eosinophils; Th1 cells; Th2 cells; therapeutics; immunopathogenesis; immunopathology; conjunctivitis; keratoconjunctivitis
(This special issue belongs to the Section Medical Research)
New Advances in Neuroimaging and Brain Functions: 2nd Edition
edited by Ming-Chang Chiang and
submission deadline 30 Sep 2024 | 1 articles | Viewed by 1701 | Submission Open
Keywords: neuroimaging; brain functions; neurological diseases; humanities and social sciences; noninvasive methods; AI deep learning
(This special issue belongs to the Section Radiobiology and Nuclear Medicine)
Kidney Transplantation: What’s Hot and What’s New
edited by and Caterina Di Bella
submission deadline 30 Sep 2024 | 1 articles | Viewed by 1206 | Submission Open
Keywords: kidney transplantation; immunosuppression; graft quality; machine perfusion (MP); living donor kidney transplantation
(This special issue belongs to the Section Medical Research)
Alternative Pharmacological Approaches for Septic Shock Management: Beyond Traditional Amine-Based Therapies
edited by Guglielmo Consales and
submission deadline 30 Sep 2024 | Viewed by 227 | Submission Open
Keywords: decatecholaminisation; non-amine-based therapy; beta blockers; hormone replacement; levosimendan; Angiotensin II; sepsis; septic shock; septic cardiomyopathy
(This special issue belongs to the Section Pharmaceutical Science)
Clinicopathology and Diagnosis of Gastric Cancer: New Advances and Perspectives
edited by Daniela Cornelia Lazar
submission deadline 30 Sep 2024 | Viewed by 66 | Submission Open
Keywords: carcinogenesis; helicobacter pylori; biomarkers; chemotherapy; immunotherapy; molecular pathways; early detection; epidemiology; genomic profiling
(This special issue belongs to the Section Medical Research)
Alzheimer’s Disease: Recent Developments in Pathogenesis, Diagnosis, and Therapy submission deadline 30 Sep 2024 | Viewed by 65 | Submission Open
Keywords: Alzheimer’ s disease; biomarkers; epigenetics; genetics; genomics; immune mediators; neurodegeneration; neuroinflammation; proteomics; risk factors; therapy; transcriptomics
(This special issue belongs to the Section Physiology and Pathology)
Microvascular Dynamics: Insights and Applications
edited by and Friedrich Jung
submission deadline 30 Sep 2024 | Viewed by 56 | Submission Open
Keywords: microvessels; dynamics; velocity; flow; rheology; in vitro; animals; humans; biomarkers; imaging; simulations; models; preclinical; clinical
(This special issue belongs to the Section Medical Research)
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