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International Journal of Molecular Sciences runs special issues to create collections of papers on specific topics. The aim is to build a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors who are experts in the subject and oversee the editorial process for papers. Papers published in a Special Issue will be collected together on a dedicated page of the journal website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Basis of Fertility Preservation and Restoration 4.0
edited by
submission deadline 30 Sep 2023 | 2 articles | Viewed by 2027 | Submission Open
Keywords: fertility preservation; infertility; testis; ovary; spermatogonia; ovarian tissue; stem cells; in vitro maturation; metabolism; miRNA; germ cells; single-cell transcriptome; induced pluripotent stem cells; organ-on-chip (OoC); organoids; microfluidic system; germ cell transplantation; epigenetics
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Advance in Carbohydrate, Lipid and Protein Metabolism
edited by and
submission deadline 30 Sep 2023 | 1 articles | Viewed by 2024 | Submission Open
Keywords: glycometabolism; lipid metabolism; amino acid metabolism; energy metabolism; metabonomics; diabetes mellitus; obesity; metabolic syndrome; dyslipidemia; inflammation; insulin resistance; nonalcoholic fatty liver
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Research of Tropical Fruit
edited by and
submission deadline 30 Sep 2023 | 3 articles | Viewed by 2017 | Submission Open
Keywords: tropical fruits; molecular research (microRNAs; genomics; transcriptomics; and proteomics); cultivation; flowering; growth and development; fruit set and development; postharvest; biotechnology and physiology; genetics
(This special issue belongs to the Section Molecular Plant Sciences)
Cellular and Molecular Research of Kidney Diseases 2.0
edited by
submission deadline 30 Sep 2023 | 1 articles | Viewed by 1997 | Submission Open
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Mendelian Randomization Approaches to Explore Complex Disease Susceptibility and Comorbidity submission deadline 30 Sep 2023 | 1 articles | Viewed by 1937 | Submission Open
Keywords: Mendelian randomization; risk factor; comorbidity; polymorphisms; complex diseases
(This special issue belongs to the Section Molecular Genetics and Genomics)
Advances in Ionic Liquids and Their Pharmaceutical Applications submission deadline 30 Sep 2023 | 1 articles | Viewed by 1906 | Submission Open
Keywords: ionic liquid; active pharmaceutical ingredient; drug delivery; human toxicity; environmental impact; pharmaceutical industry; pharmaceutical efficiency
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Gut Microbiota in Human Health submission deadline 30 Sep 2023 | 2 articles | Viewed by 1896 | Submission Open
Keywords: microbiome; colonization; immune response; microbial-derived metabolites; long-term disease; metabolism
(This special issue belongs to the Section Molecular Microbiology)
Advances in Molecular Understanding of Ocular Adnexal Disease
edited by
submission deadline 30 Sep 2023 | 3 articles | Viewed by 1857 | Submission Open
Keywords: ocular adnexa; neoplasm; carcinoma; melanoma; lymphoma; degeneration; inflammation; immune disease
(This special issue belongs to the Section Molecular Genetics and Genomics)
Molecular Research Progress on Glioblastoma
edited by
submission deadline 30 Sep 2023 | 2 articles | Viewed by 1800 | Submission Open
Keywords: glioblastoma; glioma stem cells; signaling pathways; tumor heterogeneity; tumor microenvironment; microglia; molecular pathways; immunotherapies
(This special issue belongs to the Section Molecular Oncology)
Novel Nano-Drug Delivery Systems and Their Application towards Brain Targeting submission deadline 30 Sep 2023 | 1 articles | Viewed by 1775 | Submission Open
Keywords: blood– brain barrier; central nervous system; nano-drug; drug delivery; Alzheimer’ s disease; Parkinson’ s disease; stroke; brain cancers
(This special issue belongs to the Section Molecular Nanoscience)
Novel Functions for Small Molecules
edited by
submission deadline 30 Sep 2023 | 2 articles | Viewed by 1773 | Submission Open
Keywords: small molecules; micromolecules; in vivo or vitro models
(This special issue belongs to the Section Biochemistry)
Multi-Functional Nanomaterial Based Nanosensors
edited by
submission deadline 30 Sep 2023 | 1 articles | Viewed by 1753 | Submission Open
(This special issue belongs to the Section Molecular Nanoscience)
Food Bioactive Oligosaccharides, Polysaccharides and Exopolysaccharides, Their Health Functions and Implications in Food Industry submission deadline 30 Sep 2023 | 1 articles | Viewed by 1747 | Submission Open
Keywords: bioactive oligosaccharides; human milk oligosaccharides; chitosan oligosaccharides fructo-oligosaccharides; polysaccharides; exopolysaccharides; gut microbiota; functional foods; nutrigenomics
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Latest Advancements in Aging and Longevity: Is There a Role for Precision Medicine? submission deadline 30 Sep 2023 | 2 articles | Viewed by 1746 | Submission Open
Keywords: ageing; age-related diseases; breakthroughs in ageing; hallmarks of ageing; longevity; markers; prevention; risk factors; treatment
(This special issue belongs to the Section Molecular Pharmacology)
Skin Diseases: Molecular Targets for New Therapeutics
edited by
submission deadline 30 Sep 2023 | 2 articles | Viewed by 1744 | Submission Open
Keywords: melanoma; systemic sclerosis; psoriasis; skin diseases; angiogenesis; proliferation; cell cycle; signaling pathways; fibrosis; inflammation; cell death; melanogenesis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Rational Design and Synthesis of Bioactive Molecules submission deadline 30 Sep 2023 | 3 articles | Viewed by 1741 | Submission Open
Keywords: synthesis; structure; bonding; reactivity; chemical properties; physical properties; pharmacological activity; structure-activity relationship; applications
(This special issue belongs to the Section Molecular Pharmacology)
Focus on Antioxidants and COVID-19 submission deadline 30 Sep 2023 | 2 articles | Viewed by 1732 | Submission Open
Keywords: antioxidants; COVID-19; oxidative stress; antioxidant capacity; long-COVID; vitamins
(This special issue belongs to the Section Biochemistry)
Radiation as a Double-Edged Sword: Cancer Therapy and Potential Harm
edited by
submission deadline 30 Sep 2023 | 3 articles | Viewed by 1728 | Submission Open
Keywords: radiobiological mechanisms; cancer treatment; cancer risk; normal tissue effects; cognitive impairment; immune responses; DNA damage responses; systems biology; non-targeted effects; high-LET radiation; space radiation; FLASH irradiation
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Free Radical Oxidation and Natural Antioxidants: Molecular Aspect Action
edited by
submission deadline 30 Sep 2023 | 2 articles | Viewed by 1710 | Submission Open
Keywords: reactive oxygen species (ROS); regulation of free radical oxidation; natural low-molecular-weight antioxidants; antioxidant enzymes
(This special issue belongs to the Section Bioactives and Nutraceuticals)
The Food Processing Industry’s 200th Anniversary: Bioactive Compounds, Antioxidants, and Potential Health Benefits submission deadline 30 Sep 2023 | 2 articles | Viewed by 1692 | Submission Open
Keywords: antioxidants; bioactive compounds; food processing; functional foods; green processes; health potentials; molecular mechanisms; polyphenols; shelf life; vitamins
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Advanced Ligands for Coordination Chemistry submission deadline 30 Sep 2023 | 2 articles | Viewed by 1677 | Submission Open
Keywords: ligand; complex; separation; coordination chemistry; extraction; lanthanide; actinide; metal
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Nanostructured Formulations in Pharmaceutical, Medical and Cosmetic Applications 2.0
edited by
submission deadline 30 Sep 2023 | 1 articles | Viewed by 1645 | Submission Open
Keywords: surfactants; disperse systems; colloids; nanoemulsions; lipid nanocarriers; polymeric nanocarriers; lyotropic liquid crystals; colloidal stability; drug delivery; self-organization; templating processes; encapsulation/solubilization processes; theranostics; nanohybrids
(This special issue belongs to the Section Macromolecules)
Deep Learning in Bioinformatics and Biological Data Analysis
edited by
submission deadline 30 Sep 2023 | 1 articles | Viewed by 1643 | Submission Open
(This special issue belongs to the Section Molecular Informatics)
The Path to Cure in Parkinson’s Disease: Novel Concepts on Mechanisms, Disease Modifying Treatment, and Prevention submission deadline 30 Sep 2023 | 2 articles | Viewed by 1643 | Submission Open
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Sarcomeric Proteins in Health and Disease 3.0
edited by
submission deadline 30 Sep 2023 | 2 articles | Viewed by 1595 | Submission Open
(This special issue belongs to the Section Molecular Biophysics)
Metabolic Regulation in the Development of Cardiovascular Disease and Heart Failure 2.0
edited by
submission deadline 30 Sep 2023 | 1 articles | Viewed by 1592 | Submission Open
Keywords: diabetes; metabolism; dyslipidemia; cardiovascular disease; heart failure; diagnosis; prognosis; therapy
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Regulatory Mechanisms of Development and Abiotic Stress Response by Transcriptional Regulators in Plants
edited by
submission deadline 30 Sep 2023 | 2 articles | Viewed by 1585 | Submission Open
Keywords: transcriptional regulator; transcription activation; transcription factor; transcription repression; plant development; abiotic stress response; epigenetic regulation; genome-wide analysis
(This special issue belongs to the Section Molecular Plant Sciences)
Energy Metabolism in Skeletal Muscle: From Physiology to Pharmacology submission deadline 30 Sep 2023 | 1 articles | Viewed by 1576 | Submission Open
Keywords: skeletal muscle; energy; impaired metabolism; diseases; interventions
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Mass Spectrometry in Molecular Biology
edited by
submission deadline 30 Sep 2023 | 3 articles | Viewed by 1541 | Submission Open
Keywords: mass spectrometry of biomolecules; native/modified peptides; proteins; lipids; and metabolites; sample preparation; extraction; and ionization techniques; ion fragmentation pattern recognition; statistical analysis of identification results
(This special issue belongs to the Section Molecular Informatics)
Emerging Roles of Inflammation in Retinal and Optic Nerve Pathologies submission deadline 30 Sep 2023 | 2 articles | Viewed by 1531 | Submission Open
Keywords: retina; optic nerve; neurodegeneration; disease mechanisms; neuroprotection; inflammation; senescence
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Emerging Role of RNA in Diseases and Cancers 2.0
edited by
submission deadline 30 Sep 2023 | 3 articles | Viewed by 1521 | Submission Open
Keywords: long non-coding RNAs; microRNAs; circular RNAs; RNA modifications; RNA editing; mRNA translation; alternative splicing; RNA and protein aggregation; RNA-binding proteins
(This special issue belongs to the Section Biochemistry)
Advances in Experimental and Clinical Aspects of Allergies and Autoimmunity submission deadline 30 Sep 2023 | 2 articles | Viewed by 1510 | Submission Open
Keywords: advanced diagnostics; extracellular vesicles; hypersensitivity; immune regulation; long noncoding RNA; miRNA; novel therapeutics; research models of allergy and autoimmunity
(This special issue belongs to the Section Molecular Immunology)
Melanins and Melanogenesis 4.0: From Nature to Applications submission deadline 30 Sep 2023 | 1 articles | Viewed by 1501 | Submission Open
Keywords: eumelanin; photoprotection; biological activities; antioxidant; depigmenting agents; melanogenesis; dermocosmetics; pigmentary disorders; pheomelanin; extracutaneous melanins
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Aspects of Photodynamic Therapy
edited by and Gennady A. Meerovich
submission deadline 30 Sep 2023 | 3 articles | Viewed by 1490 | Submission Open
Keywords: photosensitizer; reactive oxygen species; sensitive targets; anticancer photodynamic therapy (PDT); antimicrobial PDT; delivery carriers; molecular modeling
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Noncovalent Interactions: New Developments in Experiment and Theory submission deadline 30 Sep 2023 | 3 articles | Viewed by 1488 | Submission Open
Keywords: noncovalent interactions; computational chemistry; hydrogen bonding; halogen bonding; spectroscopy
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Determination of Chemical Composition of Natural Samples and Correlation with the Antioxidant Properties
edited by
submission deadline 30 Sep 2023 | 1 articles | Viewed by 1465 | Submission Open
Keywords: electroanalysis; spectrometry; chromatography; antioxidant; free radical
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Genetic Insights into Cardiovascular Diseases submission deadline 30 Sep 2023 | 2 articles | Viewed by 1418 | Submission Open
Keywords: cardiovascular diseases; heart disease; channelopathy; cardiomyopathy; sudden death; genetic diagnoses; gene therapy; rare mutations; common variants
(This special issue belongs to the Section Molecular Genetics and Genomics)
Tumor Microenvironment in Colorectal Cancer (Volume 2)
edited by
submission deadline 30 Sep 2023 | 1 articles | Viewed by 1411 | Submission Open
Keywords: colorectal cancer; tumor microenvironment; cancer-associated fibroblasts; endothelial cells; immune cells; extracellular matrix; tumor microenvironment biomarkers; tumor microenvironment-based clinical approaches
(This special issue belongs to the Section Molecular Oncology)
Advances in Heterogeneous Catalysts
edited by
submission deadline 30 Sep 2023 | 2 articles | Viewed by 1406 | Submission Open
Keywords: metal catalysts; oxide catalysts; catalytic reactions; functional materials; nanoparticles; defect structure; methods characterization; sol–gel; in situ
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Discovery of Gene Functions in Crops by Genome Editing and Genomics
edited by Dénes Dudits
submission deadline 30 Sep 2023 | 2 articles | Viewed by 1399 | Submission Open
Keywords: CRISPR vectors; transgenic; recombination; chromatin structure; directed mutagenesis for stress tolerance; oligonucleotide mutagenesis; in planta
(This special issue belongs to the Section Molecular Plant Sciences)
Recent Advances in Systems Metabolic Engineering Strategies
edited by
submission deadline 30 Sep 2023 | 1 articles | Viewed by 1382 | Submission Open
Keywords: systems metabolic engineering; synthetic biology; genome-scale metabolic modeling; microbial cell factory; enzyme engineering; metabolic pathway design
(This special issue belongs to the Section Biochemistry)
New Sights into Bioinformatics of Gene Regulations and Structure submission deadline 30 Sep 2023 | 1 articles | Viewed by 1381 | Submission Open
Keywords: bioinformatics; systems biology; human genomics; genomics of model organisms; gene expression regulation; transcriptomics; fundamental biomedicine; gene networks; Machine Learning in bioinformatics
(This special issue belongs to the Section Molecular Genetics and Genomics)
New Targeted Therapeutic Strategies of Multiple Myeloma submission deadline 30 Sep 2023 | 1 articles | Viewed by 1343 | Submission Open
Keywords: multiple myeloma; uncontrolled proliferation; plasmacells; immunoglobulins; natural drug therapies; immunotherapy; B cells; T cells; immunosuppressive cells; chemotherapeutics; molecular checkpoints; stem cell transplantation (ASCT); current status in MM therapy; new immunomodulatory drug/nutural compounds; monoclonal antibodies; osteoclast activity and bone resorption
(This special issue belongs to the Section Molecular Immunology)
Development of Dopaminergic Neurons 3.0
edited by
submission deadline 30 Sep 2023 | 1 articles | Viewed by 1340 | Submission Open
Keywords: neuron; dopamine; mDA; signalling pathways; human stem cell
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Mechanisms and Pathogenesis of Cardiac Diseases
edited by Yu-Hsun Kao
submission deadline 30 Sep 2023 | 1 articles | Viewed by 1337 | Submission Open
Keywords: cardiac diseases; epigenetic regulator; inflammasome; mitochondrial dysfunction; molecular mechanisms
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Gene Editing for Disease Modeling and Therapeutics
edited by
submission deadline 30 Sep 2023 | 2 articles | Viewed by 1301 | Submission Open
Keywords: gene editing methodology; CRISPR; iPSC; knockout; activation; off target; differentiation; drug discovery
(This special issue belongs to the Section Molecular Genetics and Genomics)
The Role of NRF2 in Health and Disease submission deadline 30 Sep 2023 | 2 articles | Viewed by 1281 | Submission Open
Keywords: Nrf2; disease; inflammation; oxidative stress; therapeutics; animal models studies; in vitro studies
(This special issue belongs to the Section Biochemistry)
Advances in Molecular Imaging of Breast and Gynecologic Cancers
edited by
submission deadline 30 Sep 2023 | 1 articles | Viewed by 1270 | Submission Open
Keywords: breast cancer; gynecological cancers; molecular imaging; functional imaging; radiotracer; advance nanotechnologies in oncological management
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Functional Genomes in Plant Diseases and Pests Management
edited by
submission deadline 30 Sep 2023 | 1 articles | Viewed by 1260 | Submission Open
Keywords: induced systemic resistance; genetics of plant-microbe interactions; endophytes; phytopathology; functional genomes
(This special issue belongs to the Section Molecular Plant Sciences)
Advanced Research in Functional Amyloids submission deadline 30 Sep 2023 | 3 articles | Viewed by 1241 | Submission Open
Keywords: functional bio-materials; self-assembling layer; bio-adhesion; surface/interface functionalization; functional amyloid characterization
(This special issue belongs to the Section Molecular Biophysics)
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