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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advanced Molecular Research in Tumors
edited by Keisaku Sato
submission deadline 31 Oct 2024 | 4 articles | Viewed by 4665 | Submission Open
Keywords: cancer biomarkers; cancer progression; cancer bioinformatics; immunotherapy; cancer organoids; nanoparticles; extracellular vesicles; patient-derived xenografts; artificial intelligence
(This special issue belongs to the Section Molecular Oncology)
The Potential Roles of Natural Active Products in Neurological Disorders
edited by Anna D. Serefko
submission deadline 31 Oct 2024 | 1 articles | Viewed by 2048 | Submission Open
Keywords: natural active products; phytochemicals; bioactive compounds; Neurological Disorders; depressive disorders; Parkinson's disease; depressive/epileptic episodes; antidepressants and antiepileptics; Alzheimer's disease; brain stroke; molecular mechanism; drug delivery; therapeutic potentials; structure-activity relationships; advanced therapies
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Heart Failure Mechanisms and Treatment Advances
edited by
submission deadline 31 Oct 2024 | 1 articles | Viewed by 1684 | Submission Open
Keywords: heart failure; cardiomyopathy; mechanisms; inflammation; oxidative stress; genetic susceptibility; microbiome; neurohormonal regulation; obesity and metabolic syndrome; targeted therapies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Medical Imaging Technology in Molecular Pathological Mechanisms and Disease Therapies
edited by Howard J. Halpern
submission deadline 31 Oct 2024 | 1 articles | Viewed by 1684 | Submission Open
Keywords: medical imaging; fluorescent probe; molecular imaging;oxygen; redox; cancer therapy; resistance; electron paramagnetic resonance; imaging reconstruction; tumor/cancer microenvironment; pathological mechanisms; bioinformatics; genomics analysis; anti-cancer drug discovery; toxin delivery
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Editorial Board Members’ Collection Series: Iron Homeostasis
edited by and Antonella Roetto
submission deadline 31 Oct 2024 | 2 articles | Viewed by 1650 | Submission Open
Keywords: iron metabolism; iron homeostasis; iron-deficient diseases; iron overload; ferroptosis
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Genetic Basis and Molecular Mechanisms of Heart Failure submission deadline 31 Oct 2024 | 1 articles | Viewed by 1488 | Submission Open
Keywords: heart failure; cardiomyopathies; genetics; molecular pathways; epigenetics; gene mutations
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Cellular and Molecular Biology of Cilia: Structure, Function, and Beyond
edited by
submission deadline 31 Oct 2024 | 1 articles | Viewed by 923 | Submission Open
Keywords: cilia; ciliopathy; airway biology; infertility; brain ventricle
(This special issue belongs to the Section Molecular Biology)
Molecular Research and Novel Therapy of Pancreatic Cancer
edited by Sang Seok Koh
submission deadline 31 Oct 2024 | Viewed by 323 | Submission Open
Keywords: pancreatic cancer; targeted therapy; novel drug; molecular biology; diagnostics
(This special issue belongs to the Section Molecular Oncology)
Data Science in Cancer Genomics and Precision Medicine 2.0 submission deadline 31 Oct 2024 | Viewed by 291 | Submission Open
Keywords: cancer genomics; big data; tumor immunology; translational oncology; precision medicine; next-generation sequencing; omics; cancer genomic datasets
(This special issue belongs to the Section Molecular Genetics and Genomics)
Molecular Toxicology on the Environmental Impact of Pharmaceuticals
edited by
submission deadline 31 Oct 2024 | Viewed by 200 | Submission Open
Keywords: pharmaceutic; cosmetic preparations; cosmetic products; cosmetic compounds; molecular mechanisms; environmental toxicity and/or persistence; mobility in soil/water compartment; bioconcentration or bioaccumulation
(This special issue belongs to the Section Molecular Toxicology)
Cardiac Diseases: Molecular Mechanisms and Therapeutic Strategies
edited by Jader Santos Cruz
submission deadline 31 Oct 2024 | Viewed by 174 | Submission Open
Keywords: electrophysiology; cardiac diseases; electrical signals; electrical remodeling; channels dysfunction
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Molecular Advances and Insights on Diagnosis, Prevention and Therapeutics of Cardiovascular Diseases submission deadline 31 Oct 2024 | Viewed by 173 | Submission Open
Keywords: cardiovascular disease; cardiovascular calcification; inflammation; oxidative stress; atherosclerosis; chronic kidney disease; endothelial dysfunction
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Spinocerebellar Ataxias: Uncovering Their Molecular Mechanisms, Biomarker Development, and Therapies
edited by Anna Sulek
submission deadline 31 Oct 2024 | Viewed by 147 | Submission Open
Keywords: spinocerebellar ataxia; biomarker; neurodegeneration; preclinical models; transcriptomics; proteomics; microRNA; iPSC; dynamic mutations
(This special issue belongs to the Section Molecular Neurobiology)
New Insights into Adipose Tissue Metabolic Function and Dysfunction 3.0
edited by Federica Mannino
submission deadline 31 Oct 2024 | Viewed by 78 | Submission Open
Keywords: inflammation; browning; thermogenesis; adipogenesis; diabetes; adipokines; energy storage; insulin resistance; obesity; lipolysis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Beyond Transgenics: Leveraging Humanized Mice for Disease Modeling and Therapeutics
edited by and Michael W. Melkus
submission deadline 31 Oct 2024 | Viewed by 61 | Submission Open
Keywords: humanized mouse; cancer; infectious disease; cardiovascular disease; respiratory diseases; immune diseases; lymphatic diseases; nervous system diseases; metabolic diseases; endocrine diseases; skin diseases; musculoskeletal diseases; male and female reproductive diseases; urinary diseases; rare diseases; liver disease/hepatotoxicity; humanized models of human development
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Renal Dysfunction, Uremic Compounds, and Other Factors 3.0 submission deadline 31 Oct 2024 | Viewed by 57 | Submission Open
Keywords: renal dysfunction; acute kidney disease; chronic kidney disease; soluble mediators; uremic toxins; disease progression; organ cross-talk; therapy; new techniques
(This special issue belongs to the Section Molecular Toxicology)
Molecular Studies of Mutations Related to Neurodegenerative Diseases
edited by
submission deadline 31 Oct 2024 | Viewed by 55 | Submission Open
Keywords: SNPs; mutations; structural effects; transcriptional regulation; splicing; translational regulation; post-transcriptional regulation; post-translational regulation; haploinsufficiency; nonsense mediated decay; in silico analysis; experimental analysis; missense; nonsense; frameshift; epigenetics; non-coding; coding; function alteration; stability alteration
(This special issue belongs to the Section Molecular Neurobiology)
Cytoophidia in the Molecular Sciences: Structure, Function, and Regulation
edited by
submission deadline 31 Oct 2024 | Viewed by 55 | Submission Open
Keywords: cytoophidium; filament; CTP synthase; IMPDH; intracellular compartment; metabolic cell biology; metabolic filamentation
(This special issue belongs to the Section Molecular Biology)
Chromatin Remodelers as Players and Drivers in Pathological States
edited by Matteo De March
submission deadline 31 Oct 2024 | Viewed by 55 | Submission Open
Keywords: protein structure/function; chromatin remodelers; DNA repair; oncogene/oncosuppressor; cancer
(This special issue belongs to the Section Molecular Biology)
Mechanism and Role of Adipokines in Cancer
edited by , Helen Papadaki-Petrou and
submission deadline 31 Oct 2024 | Viewed by 54 | Submission Open
Keywords: adipokines; adipose tissue; tumorigenesis; tumor microenvironment; cancer biomarkers; obesity; chemerin; leptin; adiponectin
(This special issue belongs to the Section Molecular Biology)
Molecular Insights into Glioblastoma Pathogenesis: Focus on Progenitor Cells, Microglia and Noncoding RNA
edited by
submission deadline 31 Oct 2024 | Viewed by 51 | Submission Open
Keywords: glioblastoma; tumor microenvironment; microglia; tumor-infiltrating lymphocytes; astrocytes; progenitor cells; driver mutations
(This special issue belongs to the Section Molecular Oncology)
New Trends in Neuropsychiatry Research: Behavioral and Biological Aspects
edited by
submission deadline 31 Oct 2024 | Viewed by 48 | Submission Open
Keywords: affective disorders; cognitive impairments; anxiety; depression; dementia
(This special issue belongs to the Section Molecular Neurobiology)
The Gene, Genomics, and Molecular Breeding in Cruciferae Plants 2.0
edited by
submission deadline 31 Oct 2024 | Viewed by 43 | Submission Open
Keywords: Cruciferae plants; genome analysis; genetic dissection; gene function; molecular breeding
(This special issue belongs to the Section Molecular Plant Sciences)
Development and Efficacy of Synthetic Peptide Leptin Mimetics
edited by Patricia Grasso
submission deadline 31 Oct 2024 | Viewed by 39 | Submission Open
Keywords: adrenal function; anorexia; bone turn over; diabetes; drug development; cancer; cognitive function; immune response; leptin; obesity; reproduction; serum lipids synthetic peptides
(This special issue belongs to the Section Molecular Biology)
Lung Diseases Molecular Pathogenesis and Drug Therapy
edited by
submission deadline 31 Oct 2024 | Viewed by 39 | Submission Open
Keywords: lung diseases; drug therapy; chronic obstructive pulmonary disease; lung cancer; lung fibrosis; pulmonary hypertension; asthma
(This special issue belongs to the Section Molecular Pharmacology)
Recent Advances in Alzheimer’s Disease—2nd Edition submission deadline 31 Oct 2024 | Viewed by 39 | Submission Open
Keywords: Alzheimer’ s disease; dementia; neurodegeneration; neuroinflammation; tauopathies; amyloid beta; biomarker discovery; microglia
(This special issue belongs to the Section Molecular Neurobiology)
DNA and mRNA-Based Vaccines against Infectious Diseases
edited by
submission deadline 31 Oct 2024 | Viewed by 37 | Submission Open
Keywords: mRNA vaccines; DNA vaccines; vaccine delivery; infectious disease; animal model
(This special issue belongs to the Section Molecular Immunology)
Advances in Biomedical and Tissue Engineering Strategies to Cross the Blood–Brain Barrier for Next-Generation Treatments against Neurodegenerative Diseases
edited by and Livia La Barbera
submission deadline 31 Oct 2024 | Viewed by 36 | Submission Open
Keywords: neurodegenerative diseases; Alzheimer’ s disease; CNS; blood– brain barrier; drug delivery systems; nanocarriers; nanomedicine; tissue engineering; theranostics
(This special issue belongs to the Section Molecular Neurobiology)
Nanotechnology in Drug Delivery: Applications and Perspectives
edited by Ádám Juhász
submission deadline 31 Oct 2024 | Viewed by 36 | Submission Open
Keywords: nanostructured materials; drug delivery; drug– carrier interactions; hydrogel; aerogels; associated colloids; surfactants; macromolecules; blood– brain barrier; controlled release
(This special issue belongs to the Section Molecular Nanoscience)
Novel Insights into Myeloid Neoplasms: From Pathogenesis to Targeted Therapies
edited by and Chung Hoow Kok
submission deadline 31 Oct 2024 | Viewed by 34 | Submission Open
Keywords: myeloid neoplasms; pathogenesis; targeted therapies; microenvironment; immune dysregulation
(This special issue belongs to the Section Molecular Oncology)
Roles of Iron and Iron-Related Proteins in Human Health and Diseases
edited by
submission deadline 31 Oct 2024 | Viewed by 33 | Submission Open
Keywords: iron regulation; hepcidin; ferroportin; ferritin; frataxin; HFE or HJV; lactoferrin; lipocalin; transferrin; transferrin receptor; ceruloplasmin
(This special issue belongs to the Section Molecular Biology)
Molecular Research in Gynecological Diseases-2nd Edition
edited by
submission deadline 31 Oct 2024 | Viewed by 30 | Submission Open
Keywords: malignant gynecological diseases; screening for gynecological cancers; benign gynecological conditions; screening for benign gynecological diseases; endometriosis; polycystic ovaries syndrome; ovarian cysts; uterine fibroids; leiomyomas; adenomyosis; pelvic inflammatory disease; vaginitis; vaginal dysbiosis; treatment targets for gynecological diseases
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Insights into Reproductive Biology and Related Diseases submission deadline 31 Oct 2024 | Viewed by 29 | Submission Open
Keywords: spermatozoa; oocyte; molecular reproduction; infertility
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Research and Development of Novel Electroactive Materials for Reduction/Oxidation Processes
edited by
submission deadline 31 Oct 2024 | Viewed by 29 | Submission Open
Keywords: electrochemistry; electrocatalysis; synthesis of metallic electrode materials; fabrication of alloys; crystalline structure modification; tailoring of the electrode morphology
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
New Strategies to Improve the Detection of Human Papillomavirus (HPV) Persisting Infections submission deadline 31 Oct 2024 | Viewed by 28 | Submission Open
Keywords: human papillomavirus; HPV; viral load; genotyping; oncogenic transcripts; biomarkers
(This special issue belongs to the Section Molecular Microbiology)
Advances in Molecular Biology of Pituitary Diseases submission deadline 31 Oct 2024 | Viewed by 28 | Submission Open
Keywords: pituitary adenomas; pituitary carcinomas; hypopituitarism; acromegaly; somatostatin receptor ligands; prolactinoma; Cushing’ s syndrome; TSH-secreting adenomas; syndromes of reduced sensitivity to thyroid hormones
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Research on Intracellular Signal Transduction Systems
edited by
submission deadline 31 Oct 2024 | Viewed by 27 | Submission Open
Keywords: signal transduction; receptor; G protein; kinase; second messenger; gene expression; cytoskeleton; human disease
(This special issue belongs to the Section Molecular Biology)
New Molecular Advances in Lung Cancer
edited by
submission deadline 31 Oct 2024 | Viewed by 27 | Submission Open
Keywords: lung cancer; oncogene; tyrosine kinase inhibitors
(This special issue belongs to the Section Molecular Oncology)
Molecular Genetics of Eye Diseases
edited by Hui-Ju Lin
submission deadline 31 Oct 2024 | Viewed by 26 | Submission Open
Keywords: genetic ophthalmology; genome engineering; gene phenotypes; genetic payloads; gene delivery methods; retinoblastoma; glaucoma; age-related maculopathy; keratoconjunctivitis sicca; precision medicine
(This special issue belongs to the Section Molecular Genetics and Genomics)
The Role of Purinergic Signaling in Human Health and Disease
edited by Andréia Machado Cardoso
submission deadline 31 Oct 2024 | Viewed by 25 | Submission Open
Keywords: purinergic system; purinergic receptors; ectonucleotidases; biomolecular pathways; chronic diseases; infectuous diseases; health conditions
(This special issue belongs to the Section Molecular Biology)
Rare Genetic Diseases: From Molecular Mechanisms to Therapeutic Strategies
edited by
submission deadline 31 Oct 2024 | Viewed by 23 | Submission Open
Keywords: rare genetic disease; innate metabolic errors; neurodegenerative diseases; therapeutic; molecular diagnosis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Research on Rhizobia
edited by , María J. Delgado and
submission deadline 31 Oct 2024 | Viewed by 23 | Submission Open
Keywords: biodiversity; environmental factors; plant– rhizobia interaction; nitrogen fixation; regulation; signaling; symbiosis
(This special issue belongs to the Section Molecular Microbiology)
Environmental Heavy Metals with Their Benefits and Risks for Human Health
edited by
submission deadline 31 Oct 2024 | Viewed by 22 | Submission Open
Keywords: heavy metals; metal compound; iron; copper; cadmium; arsenic; oxidative stress; cell death; toxicology; Wilson disease; hemochromatosis
(This special issue belongs to the Section Molecular Toxicology)
Cross-Talk between Mitochondrial Dysfunction and Neuroinflammation in Central Nervous System Disorders
edited by
submission deadline 31 Oct 2024 | Viewed by 21 | Submission Open
Keywords: central nervous system; mitochondria; neuroinflammation; neurodegenerative diseases; neurodevelopmental disorders
(This special issue belongs to the Section Molecular Neurobiology)
Lipids and Vitamins in Health and Disease
edited by
submission deadline 31 Oct 2024 | Viewed by 21 | Submission Open
Keywords: lipid; vitamin; metabolism; diet; nutrition
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Modeling: Latest Advances and Applications
edited by and Dan Mihailescu
submission deadline 31 Oct 2024 | Viewed by 21 | Submission Open
Keywords: molecular modeling; computational chemistry; drug design; material science; biomolecular interactions; algorithmic advances; theoretical chemistry; simulation techniques; predictive modeling; interdisciplinary applications
(This special issue belongs to the Section Molecular Biophysics)
Molecular Insight into Protein Structure and Folding
edited by
submission deadline 31 Oct 2024 | Viewed by 20 | Submission Open
Keywords: protein folding; protein function; protein structure
(This special issue belongs to the Section Molecular Biophysics)
Chemical and Molecular Characterization of Plant Bioactive Molecules
edited by
submission deadline 31 Oct 2024 | Viewed by 18 | Submission Open
Keywords: plant-based foods and by-products; plant extracts; bioactive compounds; chemical determination; biological activity; bioaccessibility; bioavailability
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Neuroimaging and Molecular Research on Depressive Disorder
edited by Keita Watanabe
submission deadline 31 Oct 2024 | Viewed by 17 | Submission Open
Keywords: neuroimaging; molecular research; neurotransmitter; depressive disorder; antidepressants
(This special issue belongs to the Section Molecular Neurobiology)
Physiological and Molecular Responses to Biotic and Abiotic Stressors in Marine Organisms
edited by and Miriam Ruocco
submission deadline 31 Oct 2024 | Viewed by 17 | Submission Open
Keywords: stress responses; marine organisms; enzymatic pathways; multiple stressors; stress markers; epigenetic response; physiological response
(This special issue belongs to the Section Molecular Biology)
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