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International Journal of Molecular Sciences runs special issues to create collections of papers on specific topics. The aim is to build a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors who are experts in the subject and oversee the editorial process for papers. Papers published in a Special Issue will be collected together on a dedicated page of the journal website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Emerging Developments in Molecular Endocrinology and Metabolic Research
edited by
submission deadline 30 Jun 2024 | Viewed by 266 | Submission Open
Keywords: endocrine feedback loops; endocrine and metabolic physiology; homeostasis; hormonal regulation; metabolic disorders; cellular and molecular mechanisms; diagnostics and therapeutics; techniques and methodologies; genomics and metabolomics; mathematical modeling
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Advances in Molecular and Cellular Imaging, Microscopy, and Biomedical Spectroscopy
edited by
submission deadline 30 Jun 2024 | Viewed by 252 | Submission Open
(This special issue belongs to the Section Molecular Biophysics)
A Commemorative Issue in Honor of József Szejtli: Advances in Cyclodextrin Chemistry and Its Applications
edited by Éva Fenyvesi, and
submission deadline 30 Jun 2024 | Viewed by 236 | Submission Open
(This special issue belongs to the Section Materials Science)
Recent Advances in Biomedical Nanocomposites and Their Functionalizations submission deadline 30 Jun 2024 | Viewed by 199 | Submission Open
Keywords: nanocarrier; drug delivery; nanoparticle; nanocapsules; nanogel; nanofiber; nanocomposite; nanocoating; cancer treatment; therapy; infection
(This special issue belongs to the Section Molecular Nanoscience)
Molecular Imaging in Nanomedical Research 4.0
edited by
submission deadline 30 Jun 2024 | Viewed by 197 | Submission Open
Keywords: nanoparticle biodistribution; light microscopy; confocal fluorescence microscopy; super-resolution microscopy; electron microscopy; scanning probe microscopy; magnetic resonance imaging; optical imaging; positron emission tomography; ultrasound imaging
(This special issue belongs to the Section Molecular Nanoscience)
Osteoporosis: From Molecular Mechanisms to Therapies 4.0
edited by
submission deadline 30 Jun 2024 | Viewed by 187 | Submission Open
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Emerging Trends in Electroconductive Materials: Functionalizations, Formulations and Composites
edited by
submission deadline 30 Jun 2024 | Viewed by 177 | Submission Open
Keywords: electroconductive materials; nanomaterials; antibacterial materials; hydrogen production; supercapacitors; batteries; biomedical application
(This special issue belongs to the Section Materials Science)
Hematopoietic System under Physiological Conditions and Following Hematopoietic Reconstitution or Stress 2.0 submission deadline 30 Jun 2024 | Viewed by 176 | Submission Open
Keywords: hematopoietic stem/progenitor cells; hematopoietic differentiation; hematopoietic niches; niche-HSC/progenitor cell interactions; steady-state hematopoiesis; reconstituted hematopoiesis; hematopoietic stress response; cell fate tracing
(This special issue belongs to the Section Molecular Biology)
Sugar Signaling in Plants and Its Interaction with Phytohormones
edited by
submission deadline 30 Jun 2024 | Viewed by 172 | Submission Open
Keywords: sugar sensing; sugar transduction pathway; interplay between sugar and hormone signaling pathways; abiotic stress; plant development; plant nutrition; epigenitic
(This special issue belongs to the Section Molecular Plant Sciences)
Neutrophil Extracellular Traps (NETs) in Immunity and Diseases 2.0
edited by
submission deadline 30 Jun 2024 | Viewed by 169 | Submission Open
Keywords: neutrophils; neutrophil functions; neutrophil extracellular traps (NETs); NETs biology; NETs in autoimmune diseases; NETs in immune response; NETs in development and progression of cancer diseases; NETs in immunothrombosis; degradation of NETs
(This special issue belongs to the Section Molecular Immunology)
Molecular Mechanisms Regulating Plant Cell Division, Differentiation
edited by
submission deadline 30 Jun 2024 | Viewed by 154 | Submission Open
Keywords: plant cell division; plant cell growth and differentiation; plant development; cell division plane orientation; cell morphogenesis
(This special issue belongs to the Section Molecular Plant Sciences)
New Molecular Therapeutic Approaches for Cystic Fibrosis submission deadline 30 Jun 2024 | Viewed by 147 | Submission Open
Keywords: cystic fibrosis; inflammation; 3D structures; organ-on-chip technology; organoids; endothelium; pulmonary disease; pathogens; drug resistance; miRNA; RNA interfering; CRISPR/Cas9; transfection; drug delivery
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advanced Research of Mitochondria-Targeted Antioxidants
edited by
submission deadline 30 Jun 2024 | Viewed by 144 | Submission Open
Keywords: antioxidants; mitochondria; biofilm; bacteria; yeast; aging; tumor; inflammation; bioenergetics; OXPHOS; metabolism
(This special issue belongs to the Section Molecular Biology)
Plant Respiration in the Light and Photorespiration submission deadline 30 Jun 2024 | Viewed by 141 | Submission Open
Keywords: plant respiratory pathways; photorespiration; leaf peroxisomes; mitochondria in the light; acclimation to environment; non-coupled respiration; electron transport chain; plant-specific respiratory components; photosynthesis– respiration interactions; global change factors; plant carbon and nitrogen metabolism; plant bioenergetics; alternative metabolic pathways
(This special issue belongs to the Section Molecular Plant Sciences)
New Biomarkers and Therapeutics in Hematological Neoplasias submission deadline 30 Jun 2024 | Viewed by 114 | Submission Open
(This special issue belongs to the Section Molecular Oncology)
The ETS Transcription Factor Family in Human Diseases
edited by George Mavrothalassitis
submission deadline 30 Jun 2024 | Viewed by 112 | Submission Open
Keywords: ETS genes; transcriptional regulation; signaling pathways; cancer; development; pharmacological intervention
(This special issue belongs to the Section Molecular Immunology)
Molecular Mechanism of pH Regulation: From Physiology to Pathology 2.0
edited by
submission deadline 30 Jun 2024 | Viewed by 110 | Submission Open
Keywords: pH regulation; acid base transporter; acid base disturbance; acidosis; intracellular pH; NBC; NHE; cancer
(This special issue belongs to the Section Molecular Biology)
Zebrafish: A Powerful Model for Genetics and Genomics 3.0
edited by
submission deadline 30 Jun 2024 | Viewed by 96 | Submission Open
Keywords: zebrafish; disease model; reverse genetics; genomics; developmental disorder; gene mutation
(This special issue belongs to the Section Molecular Genetics and Genomics)
Mesenchymal Stem/Stromal Cells and Hematological Diseases submission deadline 30 Jun 2024 | Viewed by 93 | Submission Open
Keywords: stromal microenvironment; mesenchymal stem/stromal cells; acute leukemia; chronic leukemia; chemotherapy; stem cell transplantation; regeneration
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Epigenetic Mechanisms of Cardiac Disease 2.0
edited by
submission deadline 30 Jun 2024 | Viewed by 91 | Submission Open
(This special issue belongs to the Section Molecular Genetics and Genomics)
Advanced Research on N-chlorotaurine and Other Active Halogen Taurine Derivatives submission deadline 30 Jun 2024 | Viewed by 77 | Submission Open
Keywords: N-chlorotaurine; N-bromotaurine; halogenated taurine derivatives; anti-infective; antiseptic; antimicrobial; immunity; inflammation; cancer
(This special issue belongs to the Section Molecular Pharmacology)
Role of Exosomes in Intercellular Communication
edited by Feng Dong
submission deadline 30 Jun 2024 | Viewed by 75 | Submission Open
Keywords: exosomes; intercellular communication; extracellular vehicles; small vesicles
(This special issue belongs to the Section Biochemistry)
Boosting the Production of Bioactive Compounds: Biotechnology and Metabolic Engineering of Medicinal Plants submission deadline 30 Jun 2024 | Viewed by 73 | Submission Open
Keywords: bioactive compounds; plant tissue culture; elicitors; metabolic engineering; gene expression; medicinal plants; metabolic pathway; plant biotechnology
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Advances in Heart Disease: Genomics, Proteomics, and Bioinformatics of Heart Research
edited by Justyna Fert-Bober
submission deadline 30 Jun 2024 | Viewed by 70 | Submission Open
Keywords: heart disease; cardiovascular disease; coronary artery disease (CAD); heart attack; heart failure; arrhythmia (abnormal heart rhythms); valve disease; high blood pressure; congenital heart conditions; inherited heart conditions; fibrosis; pathobiology of fibrosis; aging; chronic inflammation; inflammatory and cardiovascular diseases; myocarditis; extracellular matrix biology
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Adipose Tissue Dynamics in Laminopathies
edited by Elisa Schena
submission deadline 30 Jun 2024 | Viewed by 70 | Submission Open
Keywords: lamin A/C; prelamin A; progerin; laminopathies; adipose tissue; adipocyte differentiation; lipodystrophy; lipoatrophy; HGPS; FPLD2; MADA; EDMD
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Novel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers 3.0
edited by , and Enikö Kallay
submission deadline 30 Jun 2024 | Viewed by 65 | Submission Open
Keywords: drug design and discovery; antimicrobial drugs; antiviral drugs; antibiotics; cancer prevention and treatment; molecular modeling; molecular mechanisms; crystallography; preclinical studies; pharmacokinetics; pharmacodynamics; pharmacognosy; drug-protein interactions nuclear receptors; receptor agonists and antagonists; stem cells; activity profiling; vaccines; markers; and diagnostics; drug carriers; dosage form; anti-crystal engineering; nanoparticles; dissolution testing
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Toxicity of Foodstuff Contaminants and Mitigation Strategies
edited by and Matthew Koci
submission deadline 30 Jun 2024 | Viewed by 64 | Submission Open
Keywords: antibiotics; heavy metals; pesticides; mycotoxins; foodborne pathogens; polycyclic aromatic hydrocarbons; microplastics; toxicity; biodegradation; detoxification
(This special issue belongs to the Section Molecular Toxicology)
Pathogenesis and Novel Therapeutic Approaches for Sarcomas
edited by Francisco Giner
submission deadline 30 Jun 2024 | Viewed by 49 | Submission Open
Keywords: soft tissue tumors; bone tumors; molecular biology; target therapies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Non-coding RNAs in the Regulation of Transcription and Epigenetic Mechanisms in Complex Diseases submission deadline 30 Jun 2024 | Viewed by 45 | Submission Open
Keywords: non-coding RNAs; regulation of transcription; epigenetic mechanisms; complex diseases
(This special issue belongs to the Section Molecular Biology)
Metabolic Mechanisms of Cardiac Injury submission deadline 30 Jun 2024 | Viewed by 44 | Submission Open
Keywords: heart metabolism; fatty acid metabolism; glucose metabolism; amino acid metabolism; metabolism regulation; mitochondria
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
High Resolution Mass Spectrometry in Molecular Sciences: 2nd Edition
edited by
submission deadline 30 Jun 2024 | Viewed by 29 | Submission Open
Keywords: antibodies; astrobiology; biomarkers; drug discovery; drug development; drug metabolism; Fourier transform; glycomics; imaging; ion cyclotron resonance; ion mobility; lipids; lipidomics; mass spectrometry; metabolomics; nucleic acids; Orbitrap; organometallics; polymers; peptides; proteins; proteomics; structural biology; structure elucidation; tandem mass spectrometry; time-of-flight
(This special issue belongs to the Section Biochemistry)
Regulation and Application of Bioactive Metabolites in Plants
edited by and
submission deadline 30 Jun 2024 | Viewed by 29 | Submission Open
Keywords: medicinal plants; biosynthesis; biological activity; regulation; pharmacological mechanism
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Caenorhabditis elegans: A Model Organism for Human Health and Disease
edited by Andreia Teixeira-Castro
submission deadline 30 Jun 2024 | Viewed by 27 | Submission Open
Keywords: human physiology; human disease; therapy; novel C. elegans methods; novel C. elegans models; disease models
(This special issue belongs to the Section Molecular Biology)
Interactions between Plants and Nematodes
edited by Qian Liu
submission deadline 30 Jun 2024 | Viewed by 27 | Submission Open
Keywords: plant nematodes; hosts; interaction; effectors; giant cells; syncytia
(This special issue belongs to the Section Molecular Plant Sciences)
Multifaceted World of Chemically Modified Oligonucleotides for Nucleic Acid Therapeutics submission deadline 30 Jun 2024 | Viewed by 26 | Submission Open
Keywords: DNA and RNA analogues; phosphate mimics; sugar-modified oligonucleotides; base modifications
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Lung Injury, Regeneration, and Fibrosis 2.0
edited by
submission deadline 30 Jun 2024 | Viewed by 24 | Submission Open
Keywords: idiopathic pulmonary fibrosis; myofibroblast; extracellular matrix; infections; acute respiratory distress syndrome
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Therapeutic Potential of Antioxidants in the Prevention of Human Diseases
edited by
submission deadline 30 Jun 2024 | Viewed by 22 | Submission Open
Keywords: antioxidants; vitamins; inflammation; cancer; neurological complications; diabetes; flavonoids; natural compounds; cancer; infections; COVID-19
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Biology in Forensic Science: Past, Present and Future 2.0 submission deadline 30 Jun 2024 | Viewed by 19 | Submission Open
Keywords: genetics and molecular biology; forensic molecular biology; forensic and biological sciences; forensic genetics; aging and genetics; molecular biology and pharmacology; molecular biology and toxicology; translational pharmacology; biochemistry
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Modern NMR Characterization of Materials at the Atomic and Molecular Level
edited by
submission deadline 30 Jun 2024 | Viewed by 16 | Submission Open
Keywords: NMR; materials; dynamics; structure; diffusion; kinetics; morphology
(This special issue belongs to the Section Materials Science)
Personalized Cancer Treatment: Harnessing the Power of Molecular Research submission deadline 30 Jun 2024 | Viewed by 15 | Submission Open
Keywords: survival outcomes in oncologic setting; molecular biomarkers; advanced imaging; adaptive cancer treatment; precision cancer treatment; targeted therapies and Immunotherapy; personalized radiotherapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Paroxysmal Nocturnal Hemoglobinuria: Pathophysiology and Novel Therapeutic Approaches
edited by Jun-Ichi Nishimura
submission deadline 30 Jun 2024 | Viewed by 14 | Submission Open
Keywords: paroxysmal nocturnal hemoglobinuria; complement; intravascular hemolysis; extravascular hemolysis; breakthrough hemolysis; terminal complement inhibitor; proxymal complement inhibitor
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Scale Studies of Computational Catalysis and Density Functional Theory in Materials Chemistry
edited by
submission deadline 30 Jun 2024 | Viewed by 14 | Submission Open
Keywords: density functional theory (DFT); materials chemistry; computational catalysis; transition states; single-atom catalysts; catalyst-support interaction; Gibbs free energy; metal surfaces; transition metal complexes
(This special issue belongs to the Section Materials Science)
Advances and Applications in Molecular Enzymology
edited by
submission deadline 30 Jun 2024 | Viewed by 14 | Submission Open
Keywords: microbial enzymes; biosynthesis and bioengineering; drug development and targets; enzymes in the environment; engineered enzymes; enzymes in agri-food; enzymatic formulations; enzyme engineering; enzymes in biomedical sciences; green chemistry/technology; glycans; molecular evolution; nanocatalyst and nanotechnology; pharma enzymes; recombinant proteins production and purification; system and synthetic biology
(This special issue belongs to the Section Biochemistry)
Microbial Enzymes for Biotechnological Applications 2.0
edited by
submission deadline 30 Jun 2024 | Viewed by 14 | Submission Open
Keywords: microbial enzymes; whole-cell biocatalysts; extremozyme; enzyme assays; protein engineering
(This special issue belongs to the Section Biochemistry)
New Insights into Immunity and Inflammation in Cardiovascular Diseases
edited by
submission deadline 30 Jun 2024 | Viewed by 13 | Submission Open
Keywords: pathogens; oxidative stress; cytokines; chemokines; immunity; chronic inflammation
(This special issue belongs to the Section Molecular Immunology)
Advances in Research for Legume Genomics, Genetics, and Breeding 2.0
edited by
submission deadline 30 Jun 2024 | Viewed by 10 | Submission Open
Keywords: legumes; genomics; plant breeding; seed composition; gene function; biotic and abiotic stress; legume pathogen resistance/mechanisms
(This special issue belongs to the Section Molecular Plant Sciences)
Oncoproteins in Cancer Biology submission deadline 30 Jun 2024 | Viewed by 9 | Submission Open
Keywords: oncoproteins; cancer biology; molecular mechanisms; diagnostic applications; therapeutic targeting; tumor microenvironment; microsomes/exosomes
(This special issue belongs to the Section Molecular Oncology)
Prostate Cancer: From Molecular Diagnosis to Treatment
edited by
submission deadline 30 Jun 2024 | Viewed by 9 | Submission Open
Keywords: prostate cancer; molecular profiling; prostate cancer diagnosis; precision target therapy
(This special issue belongs to the Section Molecular Oncology)
Selected Papers for the 30th International Conference on Chelation (ICOC)—A Landmark on Metal Chelation Science and Medicine submission deadline 30 Jun 2024 | Viewed by 7 | Submission Open
Keywords: chelation therapy; metals in medicine; free radicals; ferroptosis; antioxidants; anticancer drugs; thalassaemia; other iron metabolic disorders; antimicrobials; drug design; nutraceuticals; metal complexes; diagnostic and theranostics
(This special issue belongs to the Section Molecular Pharmacology)
Environmentally Induced Oxidative Stress Toxicology
edited by
submission deadline 30 Jun 2024 | Viewed by 7 | Submission Open
Keywords: oxidative stress; environmental toxicology; environmental contaminants; inflammation; cell death; animal models
(This special issue belongs to the Section Molecular Toxicology)
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