Spinocerebellar Ataxias: Uncovering Their Molecular Mechanisms, Biomarker Development, and Therapies
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 31 October 2024 | Viewed by 128
Special Issue Editor
Special Issue Information
Dear Colleagues,
Spinocerebellar ataxias are neurodegenerative diseases that have long attracted the interest of researchers from various fields. Representing particular disease entities, some with a clearly defined genetic basis, they constitute a group of diseases with various molecular disorders that ultimately lead to the same effect: the death of neurons. In the treatment of cerebellar ataxias, the validation of clinical trial results plays an important role; hence, emphasis has been placed on the search for biomarkers that are reliable indicators of a patient’s clinical condition. The immense need to offer effective therapies may result in the advancement of research, leading to symptomatic, causal, or personalized therapies with the hope of achieving significant effects.
This Special Issue is devoted to disseminating research results on the molecular mechanisms underlying these diseases and research on their potential therapeutic targets.
We welcome everyone that may be interested in these issues to publish articles in this Special Issue, “Spinocerebellar Ataxias: Uncovering Their Molecular Mechanisms, Biomarker Development, and Therapies”, considering this group of rare neurodegenerative diseases.
Dr. Anna Sulek
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- spinocerebellar ataxia
- biomarker
- neurodegeneration
- preclinical models
- transcriptomics
- proteomics
- microRNA
- iPSC
- dynamic mutations
