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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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State-of-the-Art Molecular Biology in Romania
edited by
submission deadline 15 Apr 2024 | 9 articles | Viewed by 18909
Keywords: molecular biology; cell biology; signal transduction and regulation; gene expression; enzyme regulation; proteomics; bioinformatics
(This special issue belongs to the Section Molecular Biology)
Advances in Insulin Resistance
edited by and
submission deadline 15 Apr 2024 | 7 articles | Viewed by 18656
Keywords: insulin resistance; obesity; metabolic diseases; diabetes; metabolism; inflammation
(This special issue belongs to the Section Biochemistry)
Hormone Receptors and Signaling in Breast Cancer
edited by
submission deadline 15 Apr 2024 | 5 articles | Viewed by 17105
Keywords: breast cancer; hormone receptor; growth factor receptor; estrogen receptor; endocrine therapies; PI3K; AKT; mTOR; signaling  
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Application of Natural Products in Biomedicine and Pharmacotherapy
edited by
submission deadline 15 Apr 2024 | 10 articles | Viewed by 13530
Keywords: natural products; biomedicine; genotoxicity; epigenetics; aging
(This special issue belongs to the Section Molecular Pharmacology)
Transport Mechanisms of Mitochondrial Membrane Proteins submission deadline 15 Apr 2024 | 6 articles | Viewed by 12694
Keywords: mitochondrial carriers; transport mechanism; transport cycle; mitochondrial ADP/ATP carrier; kinetics of transport; antiport transport; uniport transport; symport transport; structures of transporters; regulation of transport; structure-function relationships of transporters; inhibitors of transporters; molecular dynamics simulations of transporters; site-directed mutagenesis; transport assays
(This special issue belongs to the Section Molecular Biology)
Microorganisms in the Environment
edited by and
submission deadline 15 Apr 2024 | 4 articles | Viewed by 12453
Keywords: Environmental microbiology; Bioremediation; Microbial biofilm; Plant– Microbe Interaction
(This special issue belongs to the Section Molecular Microbiology)
New Advance on Cancer Stem Cells
edited by
submission deadline 15 Apr 2024 | 7 articles | Viewed by 12206
Keywords: cancer stem cell; biomarker; signaling; cancer-associated fibroblast; artificial intelligence; cell therapy; antibody therapy; cell therapy; gene expression
(This special issue belongs to the Section Molecular Oncology)
Yeast as a Model System to Study Human Diseases submission deadline 15 Apr 2024 | 8 articles | Viewed by 11843
Keywords: yeast model; human disease; yeast-based drug screening; high-throughput gene interaction screening; human gene variants in yeast; humanized yeast; human– yeast protein interactions; gene complementation; stress signaling pathways; intracellular and intercellular communication
(This special issue belongs to the Section Molecular Biology)
The Role of Estrogen and Its Receptors in the Development and Therapy of Cancer submission deadline 15 Apr 2024 | 7 articles | Viewed by 11188
Keywords: estrogen; estrogen receptor; breast cancer; anticancer therapy; cancer development; cancer progression; metastasis
(This special issue belongs to the Section Molecular Oncology)
State-of-the-Art Molecular Pharmacology in USA submission deadline 15 Apr 2024 | 4 articles | Viewed by 10623
Keywords: signal transduction; receptor; animal models; preclinical; pharmacodynamics; pharmacokinetics; drug development; drug metabolism
(This special issue belongs to the Section Molecular Pharmacology)
Macrophage Polarization: Learning to Manage It 3.0
edited by
submission deadline 15 Apr 2024 | 7 articles | Viewed by 10497
Keywords: macrophages; macrophage plasticity; macrophage polarization; innate immunity; IFN-γ ; TNF-α ; immunomodulators; diseases; homeostasis; inflammation; cancer
(This special issue belongs to the Section Molecular Immunology)
Ovary and Testis: Molecular Biological Insights
edited by and Frank Nawroth
submission deadline 15 Apr 2024 | 8 articles | Viewed by 10019
Keywords: mammalian; human; ovary; testis; molecular; biology; physiology; fertility; sterility; follicles; oogenesis; spermatogenesis; gene; molecular genetics; genome; expression; DNA; RNA; cooling; cryopreservation; freezing; transplantation; proteomics; genomics; transcriptomics; metabolomics; apoptosis; cancer
(This special issue belongs to the Section Molecular Biology)
Advanced Research in Retina 2.0 submission deadline 15 Apr 2024 | 8 articles | Viewed by 9949
Keywords: glaucoma; age-related macular degeneration; diabetic retinopathy; neurodegenerative diseases; diagnostic techniques; therapeutic strategies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Role of Mg Homeostasis in Disease submission deadline 15 Apr 2024 | 7 articles | Viewed by 9685
Keywords: magnesium; chronic diseases; diabetes; bone disease; mineral metabolism; renal disease; inflammation; cardiovascular disease
(This special issue belongs to the Section Biochemistry)
Challenges, Opportunities, and Innovation in Functional Nanomaterials and Polymer Nanocomposites submission deadline 15 Apr 2024 | 3 articles | Viewed by 9553
Keywords: smart nanoparticles; synthesis and characterization; polymer nanocomposites; energy applications; biomedical applications; environmental applications
(This special issue belongs to the Section Molecular Nanoscience)
Hunting for Prospective Molecular Approaches to Prevent Cardiac Arrhythmias
edited by
submission deadline 15 Apr 2024 | 6 articles | Viewed by 9187
Keywords: inflamed and stressed heart; pro-arrhythmic autonomic misbalance; pro-arrhythmic hormone misbalance; cardiac channelopathies; connexins and hemichannels; conduction disturbances; novel anti-arrhythmic targets; multitargeted strategies; non-invasive antiarrhythmic approaches; antiarrhythmic potential of cardioprotective drugs
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Kidney Diseases: From Molecular Basis to Therapy
edited by
submission deadline 15 Apr 2024 | 6 articles | Viewed by 8909
Keywords: chronic kidney disease  ; molecular mechanisms  ; oxidative stress  ; inflammation
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Current Advances in Metal Complexes with Biological Activity submission deadline 15 Apr 2024 | 5 articles | Viewed by 8827
Keywords: metal-based drugs; drug discovery; anticancer activity; antibacterial activity; transition metal complexes
(This special issue belongs to the Section Molecular Pharmacology)
Silk-Based Functional Materials: New Ways of Production, Properties and Applications submission deadline 15 Apr 2024 | 4 articles | Viewed by 8605
Keywords: fibroin; sericin
(This special issue belongs to the Section Materials Science)
Advanced Catalytic Materials submission deadline 15 Apr 2024 | 9 articles | Viewed by 8438
Keywords: synthetic routes; nanomaterials; catalysis; sustainability; biomass; biofuel; photocatalysis; fine chemistry
(This special issue belongs to the Section Materials Science)
The Advances in Antimicrobial Biomaterials submission deadline 15 Apr 2024 | 6 articles | Viewed by 8308
Keywords: biomaterials; biopolymers production; antimicrobial agents; antimicrobial activity; natural antibiotics; antioxidants; bioelastomers; food packaging
(This special issue belongs to the Section Materials Science)
Transcription Factors in Lung Cancer: Mechanisms and Future Perspectives submission deadline 15 Apr 2024 | 5 articles | Viewed by 7555
Keywords: transcription factors; lung cancer; NSCLC SCLC; targeting; biomarkers; tumor suppressors; oncogenes; transcription factor network; computational models
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Interplay among Biomolecules and Nanomaterials
edited by
submission deadline 15 Apr 2024 | 4 articles | Viewed by 7484
Keywords: biomolecules; nanomaterials; medical materials; fluorescent probe; drug transport; toxicity; nutrition; biocompatibility  
(This special issue belongs to the Section Materials Science)
Wound Healing and Hypertrophic Scar
edited by
submission deadline 15 Apr 2024 | 4 articles | Viewed by 7449
Keywords: scar; fibrosis; wound healing; keloids; inflammation; rehabilitation; scleroderma; organ fibrosis; pruritus; pain
(This special issue belongs to the Section Molecular Biology)
Molecular Approach to Fern Development
edited by
submission deadline 15 Apr 2024 | 5 articles | Viewed by 7270
Keywords: apomixis; apogamy; asexual reproduction; fern; proteomics; genomics; plant development; evo-devo; plant biotechnology
(This special issue belongs to the Section Molecular Plant Sciences)
Alternative Splicing: From Abiotic Stress Tolerance to Evolutionary Genomics 2.0 submission deadline 15 Apr 2024 | 5 articles | Viewed by 7149
Keywords: alternative splicing; Iso-Seq; PacBio; exon skipping; intron retention; abiotic stress; water deficit; desiccation tolerance
(This special issue belongs to the Section Molecular Plant Sciences)
The 25th Anniversary of NO submission deadline 15 Apr 2024 | 4 articles | Viewed by 6932
Keywords: nitric oxide; gasotransmitter; NO-synthase; nitrosation; nitrosylation
(This special issue belongs to the Section Biochemistry)
Skeletal Muscle Adaptations to Oxidative Stress
edited by
submission deadline 15 Apr 2024 | 4 articles | Viewed by 6789
Keywords: oxidative stress; exercise; physical activity; skeletal muscle; muscle damage; antioxidants; reactive oxygen species; redox balance; aging; nutrition
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Bioactive Glucosinolates and Derivatives submission deadline 15 Apr 2024 | 5 articles | Viewed by 6569
Keywords: glucosinolate; isothiocyanate; myrosinase; Brassicales; chemical characterization; biological characterization; mechanism of action; stability; functionality; biopesticides; biostimulants; nutraceuticals
(This special issue belongs to the Section Bioactives and Nutraceuticals)
State-of-the-Art Molecular Biophysics in USA submission deadline 15 Apr 2024 | 3 articles | Viewed by 6560
Keywords: protein structure; protein dynamics; ion channels; molecule biophysics; drug delivery; energy
(This special issue belongs to the Section Molecular Biophysics)
From Bench to Bedside: Comprehensive Research on Cardiomyopathy
edited by
submission deadline 15 Apr 2024 | 3 articles | Viewed by 6487
Keywords: cardiomyopathy; chronic heart failure; pathological remodeling; left ventricular hypertrophy; right heart failure; echocardiography; cell signaling
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Research of Escherichia coli K-12 submission deadline 15 Apr 2024 | 3 articles | Viewed by 6461
Keywords: Escherichia coli; proteobacteria; genome; gene function; gene regulation; y-based names; de-orphanization; centennial
(This special issue belongs to the Section Molecular Microbiology)
Nitric Oxide Signalling and Metabolism in Plants 2023 submission deadline 15 Apr 2024 | 5 articles | Viewed by 6211
Keywords: plant growth and development; postharvest; abiotic stress; fruit ripening; cut-flower; signal interactions; signal pathways; protein modification; gene regulation
(This special issue belongs to the Section Molecular Plant Sciences)
Alcohol and Inflammation
edited by and Emilio González-Reimers
submission deadline 15 Apr 2024 | 3 articles | Viewed by 5984
Keywords: alcohol; inflammation; alcohol use disorder; alcoholic liver disease; liver disease; alcoholic hepatitis; liver injury; oxidative damage
(This special issue belongs to the Section Molecular Immunology)
Inflammation and Cancer 2023 submission deadline 15 Apr 2024 | 5 articles | Viewed by 5974
Keywords: inflammation; cytokines; gut microbiota; insulin resistance; molecular biology; autophagy; epithelial-to-mesenchymal transition (EMT); tumor microenvironment  
(This special issue belongs to the Section Molecular Oncology)
Selected Papers from 12th International Symposium on Targeted Alpha Therapy
edited by
submission deadline 15 Apr 2024 | 3 articles | Viewed by 5638
Keywords: precision oncology; oncology; radionuclide therapy; targeted therapy; targeted alpha therapy; Lead radioisotopes; Bismuth radioisotopes; Radium radioisotopes; Actinium radioisotopes; Thorium radioistotopes; PSMA; prostate cancer; endocrine; neuroendocrine neoplasms; somatostatin analogs; Monte Carlo; computational methods; daughter radionuclides; dosimetry; small-scale/microdosimetry; targeted alpha therapy; radiobiology; target chemistry
(This special issue belongs to the Section Molecular Biology)
Development of Vaccines against Arboviruses submission deadline 15 Apr 2024 | 3 articles | Viewed by 5572
Keywords: arbovirus; vaccine development; vaccine platforms; molecular biology techniques; immune response; preclinical evaluation; clinical testing
(This special issue belongs to the Section Molecular Immunology)
Molecular Research on SARS-CoV-2
edited by
submission deadline 15 Apr 2024 | 3 articles | Viewed by 5566
Keywords: SARS-CoV-2; COVID-19; molecular surveillance; variants; molecular epidemiology; infection prevention; outbreak; therapy; diagnostic
(This special issue belongs to the Section Molecular Microbiology)
Lipidomics of Human Disease
edited by Evros Vassiliou and
submission deadline 15 Apr 2024 | 1 articles | Viewed by 5481
Keywords: docosahexaenoic acid; eicosapentaenoic acid; arachidonic acid; inflammation; prostaglandins; apoptosis; bioavailability; peroxidation; reactive oxygen species
(This special issue belongs to the Section Macromolecules)
Advances in Pharmacology of Prostaglandins submission deadline 15 Apr 2024 | 2 articles | Viewed by 5464
Keywords: anti-inflammatory drugs; prostaglandin level modulators; agonists and antagonists of prostaglandin receptors; chronic inflammatory diseases; cardiovascular diseases; neuroinflammation; autoimmune diseases; gastrointestinal diseases; respiratory tract; cancer
(This special issue belongs to the Section Molecular Pharmacology)
Carbonic Anhydrases as Key Biocatalysts in CO2 Dynamics: From Biochemistry to Biomedical and Biotechnological Applications
edited by
submission deadline 15 Apr 2024 | 3 articles | Viewed by 5303
Keywords: metalloenzyme; catalysis; inhibitor; activator; selective toxicity; biomedical applications; biotechnological applications
(This special issue belongs to the Section Biochemistry)
Metal-Based Drugs and Research on Mechanisms of Action submission deadline 15 Apr 2024 | 3 articles | Viewed by 5136
Keywords: transition metals; metal complexes; metallodrugs; drug development; synthesis; imaging agents; structure– activity ratio
(This special issue belongs to the Section Molecular Pharmacology)
Human Cells Response to Light submission deadline 15 Apr 2024 | 2 articles | Viewed by 4868
Keywords: light-emitting diodes (LEDs); oxidative stress; mitochondria; cell viability; apoptosis; cellular stress response
(This special issue belongs to the Section Molecular Biology)
Novel Targeted Therapies and Drugs in Cancer submission deadline 15 Apr 2024 | 3 articles | Viewed by 4818
Keywords: targeted therapies; genetic mutation; PARP inhibitors; immunotherapy; drug development; cancer molecular analysis; drug response; molecular-targeted therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Radiation as a Double-Edged Sword: Cancer Therapy and Potential Harm
edited by
submission deadline 15 Apr 2024 | 4 articles | Viewed by 4682
Keywords: radiobiological mechanisms; cancer treatment; cancer risk; normal tissue effects; cognitive impairment; immune responses; DNA damage responses; systems biology; non-targeted effects; high-LET radiation; space radiation; FLASH irradiation
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Cardiovascular Disease, Atherosclerosis and Familial Hypercholesterolemia 3.0 submission deadline 15 Apr 2024 | 3 articles | Viewed by 4668
Keywords: cardiovascular disease; atherosclerosis; familial hypercholesterolemia
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Activation of the Blood–Brain Barrier and Neurological Dysfunction
edited by
submission deadline 15 Apr 2024 | 2 articles | Viewed by 4636
Keywords: blood– brain barrier; neuro-infectious diseases; cerebral malaria; Plasmodium; cerebral vasculature; vascular heterogeneity; white matter; gray matter
(This special issue belongs to the Section Molecular Neurobiology)
Osteoarthritis: From Molecular Mechanism to Novel Therapy
edited by
submission deadline 15 Apr 2024 | 4 articles | Viewed by 4583
Keywords: osteoarthritis; joint inflammation; cartilage and chondrocyte function; cartilage regeneration and repair; post-traumatic osteoarthritis; synovium
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Comparative Genomics and Functional Genomics Analysis in Plants 2.0
edited by and Ran Su
submission deadline 15 Apr 2024 | 3 articles | Viewed by 4541
Keywords: de novo genome sequencing; pan-genomic analyses; genome re-sequencing; WAS analyses; RNA-seq; metabolomics; gene family analyses; plant evolutionary analyses; bioinformatics; database  
(This special issue belongs to the Section Molecular Informatics)
Drug Toxicity in Disease Therapy
edited by
submission deadline 15 Apr 2024 | 3 articles | Viewed by 4439
Keywords: drug toxicity; toxic drug interactions; drug management; therapeutic drug monitoring
(This special issue belongs to the Section Molecular Toxicology)
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