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The Role of Purinergic Signaling in Human Health and Disease

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: 31 October 2024 | Viewed by 52

Special Issue Editor


E-Mail Website
Guest Editor
Graduate Program in Biomedical Sciences, Medicine Course, Member of the Brazilian Purine Club, Federal University of Fronteira Sul, Fronteira Sul, Campus Chapecó, Rodovia SC 484-Km 02, Chapecó 89815-899, SC, Brazil
Interests: purinergic signaling; ectonucleotidases; P1 receptors; P2 receptors; ATP; adenosine; physical exercise; chronic diseases; infectuous diseases

Special Issue Information

Dear Colleagues,

This Special Issue on purinergic signaling in health and disease delves into the multifaceted roles of purinergic signaling in various physiological processes and pathologies. Purinergic signaling involves the release of purines, such as ATP and adenosine, which act as extracellular signaling molecules, modulating cellular functions through purinergic receptors.

The Special Issue covers the fundamental mechanisms of purinergic signaling, including purine release, receptor activation, and downstream signaling pathways. It explores the diverse functions of purinergic signaling in different organ systems, including the nervous, immune, cardiovascular, and musculoskeletal systems.

Furthermore, this Special Issue addresses the involvement of purinergic signaling in various diseases, such as neurological disorders, autoimmune diseases, cardiovascular diseases, and cancer. It discusses how dysregulation of purinergic signaling can contribute to disease pathogenesis and progression, highlighting the potential of purinergic receptors and signaling pathways as therapeutic targets.

This Special Issue on purinergic signaling in health and disease aims to explore the intricate roles of purinergic signaling in various physiological processes and pathological conditions. It covers fundamental mechanisms of purinergic signaling, its involvement in different organ systems, and its contribution to diseases such as neurological disorders, autoimmune diseases, cardiovascular diseases, and cancer. The Special Issue provides a focused examination of the current understanding of purinergic signaling and its potential implications for therapeutic interventions. Papers with biomolecular experiments are welcome.

Dr. Andréia Machado Cardoso
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • purinergic system
  • purinergic receptors
  • ectonucleotidases
  • biomolecular pathways
  • chronic diseases
  • infectuous diseases
  • health conditions

Published Papers

This special issue is now open for submission.
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