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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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State-of-the-Art Molecular Immunology in Japan submission deadline 18 Apr 2024 | 4 articles | Viewed by 8080
(This special issue belongs to the Section Molecular Immunology)
Therapeutic Targets in Pancreatic Cancer submission deadline 20 Apr 2024 | 12 articles | Viewed by 14742 | Submission Open
Keywords: pancreatic cancer; translational research; therapeutic targets and novel interventional strategies; mechanisms of anti-tumor reactions; biomarkers
(This special issue belongs to the Section Molecular Oncology)
New Insights into Adipose Tissue Metabolic Function and Dysfunction 2.0 submission deadline 20 Apr 2024 | 8 articles | Viewed by 12762 | Submission Open
Keywords: inflammation; browning; thermogenesis; adipogenesis; diabetes; adipokines; energy storage; insulin resistance; obesity; lipolysis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
70 Years of Oxytocin: Updates on Groundbreaking Findings 70 Years after the Discovery of Oxytocin
edited by
submission deadline 20 Apr 2024 | 5 articles | Viewed by 11408 | Submission Open
Keywords: oxytocin; energy; metabolism; metabolic syndrome; skeletal muscle; bone; Prader– Willi syndrome; autism; body composition; thermoregulation
(This special issue belongs to the Section Molecular Biology)
New Targets and Approaches for the Treatment of Alzheimer's Disease and Related Disorders submission deadline 20 Apr 2024 | 7 articles | Viewed by 11088 | Submission Open
Keywords: Alzheimer’ s disease; dementia; ALS; Parkinsonism; neurodegeneration; neuroprotective agents; neuroactive peptides
(This special issue belongs to the Section Molecular Neurobiology)
High-Density Lipoproteins in Health and Disease
edited by
submission deadline 20 Apr 2024 | 6 articles | Viewed by 10467 | Submission Open
Keywords: omics; protein; lipid; cardiovascular; neurodegenerative disease; inflammation; preclinical studies; therapy
(This special issue belongs to the Section Molecular Biology)
Metabolomics in Health and Disease 2.0
edited by
submission deadline 20 Apr 2024 | 7 articles | Viewed by 10031 | Submission Open
Keywords: biomarkers; mass spectrometry; NMR; alternative analytical platforms for metabolomics; data processing workflows; computational biomarker discovery; volatile metabolomics; cancer; neurodegenerative diseases; cardiovascular diseases; epidemiology; rare diseases
(This special issue belongs to the Section Biochemistry)
PD-L1, a Master Regulator of Immunity in Health and Disease submission deadline 20 Apr 2024 | 4 articles | Viewed by 7269 | Submission Open
Keywords: PD-1; PD-L1; T cell; immune checkpoint; myeloid cell; biomarker; cancer; auto-immunity; infectious disease
(This special issue belongs to the Section Biochemistry)
State-of-the-Art Molecular Oncology in Mexico, 2nd Edition submission deadline 20 Apr 2024 | 6 articles | Viewed by 7225 | Submission Open
Keywords: cancer; metastasis; molecular oncology; chemoresistance; Mexico; epidemiology
(This special issue belongs to the Section Molecular Oncology)
The Food Processing Industry’s 200th Anniversary: Bioactive Compounds, Antioxidants, and Potential Health Benefits submission deadline 20 Apr 2024 | 4 articles | Viewed by 5983 | Submission Open
Keywords: antioxidants; bioactive compounds; food processing; functional foods; green processes; health potentials; molecular mechanisms; polyphenols; shelf life; vitamins
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Advances in Inflammatory Bowel Diseases 2.0
edited by
submission deadline 20 Apr 2024 | 4 articles | Viewed by 5396 | Submission Open
Keywords: inflammatory bowel disease; adipose stem cells; gut microbiota; immunologic and molecular mechanisms; therapeutical approaches
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Recent Advances in Biosurfactants submission deadline 20 Apr 2024 | 3 articles | Viewed by 5209 | Submission Open
Keywords: tensioactive molecules; surface adhesion; antimicrobial activity; antibiofilm activity; emulsions; drug delivery
(This special issue belongs to the Section Materials Science)
Pathogenesis and Treatments of Head and Neck Cancer
edited by
submission deadline 20 Apr 2024 | 2 articles | Viewed by 5104 | Submission Open
Keywords: HNSCC; premalignant changes; tumor microenvironment; molecular biomarkers; targeted therapy; oral tumorigenesis; molecular pathogenesis; tumor biology; tumor immunology
(This special issue belongs to the Section Molecular Oncology)
Nitric Oxide Signalling in Plants
edited by
submission deadline 20 Apr 2024 | 2 articles | Viewed by 4476 | Submission Open
Keywords: nitric oxide; NO-mediated transcriptome; post-transcription modification; S-nitrosylation; N assimilation; NO homeostasis; gaseous NO; cellular signaling; nitric oxide signaling; transcription factors (TFs)  
(This special issue belongs to the Section Molecular Plant Sciences)
Emerging Roles of Inflammation in Retinal and Optic Nerve Pathologies submission deadline 20 Apr 2024 | 4 articles | Viewed by 4210 | Submission Open
Keywords: retina; optic nerve; neurodegeneration; disease mechanisms; neuroprotection; inflammation; senescence
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Investigation of Natural Products as Sources of Bioactive Molecules
edited by
submission deadline 20 Apr 2024 | 4 articles | Viewed by 3994 | Submission Open
Keywords: metabolomic; secondary metabolites; phytochemical analysis; bioactivity; chemical investigation
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Pancreatic Disease: From Molecular Basis to Novel Therapies submission deadline 20 Apr 2024 | 4 articles | Viewed by 3965 | Submission Open
Keywords: pancreatitis; acinar-to-ductal neoplasia; early pancreatic neoplasia; fibroinflammatory disease; pancreatic cancer; Diabetes Mellitus
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Pathogenesis and Management of Mastocytosis
edited by
submission deadline 20 Apr 2024 | 2 articles | Viewed by 3708 | Submission Open
Keywords: mastocytosis; pathogenesis; pathophysiology; pathology; mutations; targeted therapy
(This special issue belongs to the Section Molecular Immunology)
Nanotechnology Applications in Antimicrobials submission deadline 20 Apr 2024 | 2 articles | Viewed by 3642 | Submission Open
Keywords: drug delivery; antimicrobial therapy; biofilm inhibition; microbial resistance; nanobiomaterials; nanostructures
(This special issue belongs to the Section Materials Science)
Novel Functions for Small Molecules
edited by
submission deadline 20 Apr 2024 | 3 articles | Viewed by 3619 | Submission Open
Keywords: small molecules; micromolecules; in vivo or vitro models
(This special issue belongs to the Section Biochemistry)
G Protein-Coupled Receptor Signaling in Molecular and Cellular Physiology submission deadline 20 Apr 2024 | 2 articles | Viewed by 3540 | Submission Open
Keywords: GPCR; signal transduction; molecular physiology; disease; cellular pathophysiology
(This special issue belongs to the Section Molecular Biology)
Studies on Proton-Gated Ion Channels: Structural Aspects, Pharmacology and Implications in Health and Disease
edited by
submission deadline 20 Apr 2024 | 3 articles | Viewed by 3393 | Submission Open
Keywords: acid-sensing ion channels; other proton-gated ion channels; modulators of proton-gated ion channels; structural-functional analysis; animal models; cognitive functions; inflammatory diseases; pain  
(This special issue belongs to the Section Molecular Biophysics)
Glycoconjugates Function and Metabolism
edited by
submission deadline 20 Apr 2024 | 2 articles | Viewed by 3330 | Submission Open
Keywords: glycosylation; glycoconjugates; glycolipids; gangliosides; glycoproteins
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Interaction between Metal Compounds and Proteins 2.0
edited by
submission deadline 20 Apr 2024 | 2 articles | Viewed by 3299 | Submission Open
Keywords: bioinorganic chemistry; metallodrugs; metalloproteins; metallopeptides; metal binding sites; metallomics
(This special issue belongs to the Section Biochemistry)
Advances in Endoplasmic Reticulum Stress and Apoptosis submission deadline 20 Apr 2024 | 4 articles | Viewed by 2828 | Submission Open
Keywords: ER stress; apoptosis initiated by ER stress; cellular survival; redox homeostasis of ER; autophagy initiated by ER stress; cell death pathways initiated by ER stress
(This special issue belongs to the Section Biochemistry)
Molecular and Cellular Mechanisms of Idiopathic Pulmonary Fibrosis and Interstitial Lung Diseases 2.0 submission deadline 20 Apr 2024 | 2 articles | Viewed by 2802 | Submission Open
Keywords: lung fibrosis; idiopathic pulmonary fibrosis; interstitial lung disease; molecular pathways; cellular aging and senescence
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Diagnostic Strategies for Prediction and Prognosis of Gastric Cancer
edited by
submission deadline 20 Apr 2024 | 2 articles | Viewed by 2767 | Submission Open
Keywords: prognostic biomarker; predictive biomarker; gastric cancer; molecular diagnostic strategy; solid biopsy; liquid biopsy; real-time PCR; digital PCR; next-generation sequencing
(This special issue belongs to the Section Molecular Oncology)
New Insights into the Role of the Renin–Angiotensin System in Disease
edited by
submission deadline 20 Apr 2024 | 2 articles | Viewed by 2360 | Submission Open
Keywords: angiotensin II; angiotensin-converting enzyme; cytokines; cardiovascular disease; immune pathways; inflammation; inflammatory signaling; infection; renin– angiotensin system; SARS-CoV-2
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Neurodegenerative Retinal Diseases and Other Neurodegenerative Pathologies
edited by Salvador Pastor-Idoate and
submission deadline 20 Apr 2024 | 1 articles | Viewed by 1728 | Submission Open
Keywords: neurodegeneration; retina; molecular biology; genetics and cellular biology
(This special issue belongs to the Section Molecular Neurobiology)
New Insights into Glioblastoma: Cellular and Molecular 2.0
edited by
submission deadline 20 Apr 2024 | 2 articles | Viewed by 1561 | Submission Open
Keywords: glioblastoma; glioma; brain tumors; targeted therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Recent Advances and Techniques for the Vascularization of Tissue Engineering Constructs submission deadline 20 Apr 2024 | 1 articles | Viewed by 1431 | Submission Open
Keywords: tissue engineering; vascularization; vasculogenesis; angiogenesis; biomaterials
(This special issue belongs to the Section Molecular Biology)
New Trends in Alzheimer’s Disease Research: From Molecular Mechanisms to Therapeutics 2.0
edited by
submission deadline 20 Apr 2024 | 1 articles | Viewed by 1131 | Submission Open
Keywords: Alzheimer’ s disease; pathogenic mechanisms; genomics; epigenetics; biomarkers; prevention; treatment; pharmacogenetics
(This special issue belongs to the Section Molecular Neurobiology)
The Role of Phytochemicals in Neurological Disorders submission deadline 20 Apr 2024 | 1 articles | Viewed by 1049 | Submission Open
Keywords: phytochemicals; neurodegeneration; antioxidant activity; anti-inflammatory activity; nutrition; bioactive; inhibitor; functional foods; nutraceuticals; molecular mechanism
(This special issue belongs to the Section Bioactives and Nutraceuticals)
New Amphiphilic Molecules for Biomedical Applications
edited by
submission deadline 20 Apr 2024 | 1 articles | Viewed by 992 | Submission Open
Keywords: amphiphilic polymers and biopolymers; macromolecules of complex topology; self-assembling; synthesis; characterization; computer simulation; drug and gene delivery; nanomedicine
(This special issue belongs to the Section Molecular Biology)
Cellular and Molecular Mechanisms Governing Liver Homeostasis
edited by
submission deadline 20 Apr 2024 | 1 articles | Viewed by 938 | Submission Open
Keywords: liver; physiopathology; immune-mediated liver disease; metabolic liver disease; experimental cirrhosis; experimental hepatitis/steatosis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Natural Products as Multitarget Agents in Human Diseases submission deadline 20 Apr 2024 | 1 articles | Viewed by 914 | Submission Open
Keywords: natural products; bioactive compounds; human health; disease prevention and treatment; molecular and physiological mechanism; inflammatory diseases; cancer; arthritic diseases  
(This special issue belongs to the Section Molecular Pharmacology)
New Molecular Insights in Mitochondrial Medicine
edited by
submission deadline 20 Apr 2024 | 1 articles | Viewed by 809 | Submission Open
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Human Carbonic Anhydrase Family as Target for Drug Design submission deadline 20 Apr 2024 | Viewed by 478 | Submission Open
(This special issue belongs to the Section Molecular Pharmacology)
Advances in the Molecular Biology of Lung Disease 2.0
edited by
submission deadline 20 Apr 2024 | Viewed by 327 | Submission Open
Keywords: severe asthma; COPD; lung cancer; pathology; molecular biomarkers; interstitial lung diseases; immunobiology; omics; prognosis; pathogenesis; proteomics; genetics
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Research Progress of Familial Mediterranean Fever
edited by Gernot Kriegshäuser
submission deadline 20 Apr 2024 | Viewed by 257 | Submission Open
Keywords: Familial Mediterranean fever; pyrin; inflammasome; genotype-phenotype correlation; genetic epidemiology; disease modifying factor  
(This special issue belongs to the Section Molecular Biology)
Drug-Induced Modulation and Immunotherapy of Leukemia
edited by Helga Maria Schmetzer
submission deadline 20 Apr 2024 | Viewed by 255 | Submission Open
Keywords: leukemia; dendritic cells; immunotherapy; immune modulation
(This special issue belongs to the Section Molecular Immunology)
Antibody Therapy for Hematologic Malignancies submission deadline 20 Apr 2024 | Viewed by 253 | Submission Open
Keywords: hematologic malignancies; leukemia; lymphoma; antibody therapy; immune therapy; cellular therapy; combination therapy; bispecific; BiTE; trispecific; tumor antigens; Fc receptors; signaling; microenvironment
(This special issue belongs to the Section Molecular Oncology)
The Role of Autophagy Processes in Neurodegenerative Diseases
edited by
submission deadline 20 Apr 2024 | Viewed by 251 | Submission Open
Keywords: neurodegenerative diseases; aggregate-prone proteins; autophagy; mitophagy; autophagosome; lysosome
(This special issue belongs to the Section Molecular Neurobiology)
Advances and Perspectives in Nucleic Acid Memory
edited by
submission deadline 20 Apr 2024 | Viewed by 232 | Submission Open
Keywords: DNA memory; DNA digital data storage; nucleic acid memory; information storage; DNA nanotechnology; molecular information
(This special issue belongs to the Section Molecular Biology)
How Are Predicted Protein Structures Advancing the Development of New Drugs?
edited by
submission deadline 20 Apr 2024 | Viewed by 171 | Submission Open
Keywords: protein structural dynamics; molecular dynamics simulation; structural drug; drug safety; DNA sequence; predicted protein structures; protein structure-function relationships
(This special issue belongs to the Section Molecular Informatics)
Cancers: Drug Design, Development and Therapy
edited by
submission deadline 20 Apr 2024 | Viewed by 131 | Submission Open
Keywords: combination therapy; acquired resistance; proteomics; AI
(This special issue belongs to the Section Molecular Oncology)
Vasculitis: From Molecular Biology to Therapy
edited by
submission deadline 20 Apr 2024 | Viewed by 123 | Submission Open
Keywords: vasculitis; immunopathology; diagnosis; therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
In Vitro and In Vivo Models of Cancer Progression
edited by and Emanuela Guerra
submission deadline 20 Apr 2024 | Viewed by 121 | Submission Open
Keywords: tumour biology; cancer progression; cancer microenvironment; in vitro and in vivo models; patient-derived xenografts; patient-derived organoids; organs-on-a-chip; multi-omics; drug discovery; drug repositioning
(This special issue belongs to the Section Molecular Oncology)
Application of Natural Products in Prevention of Bone Related Diseases submission deadline 22 Apr 2024 | 2 articles | Viewed by 2320 | Submission Open
Keywords: osteoporosis; natural products; functional food; clinical application; menopause; osteoarthritis; bone-related diseases; alternative therapy  
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advanced Research in Plant-Fungi Interactions
edited by
submission deadline 23 Apr 2024 | 7 articles | Viewed by 6892 | Submission Open
Keywords: plant-fungus interactions; symbiotic association; endophytes; plant conservation; mycorrhizal symbioses
(This special issue belongs to the Section Molecular Plant Sciences)
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