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International Journal of Molecular Sciences runs special issues to create collections of papers on specific topics. The aim is to build a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors who are experts in the subject and oversee the editorial process for papers. Papers published in a Special Issue will be collected together on a dedicated page of the journal website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Advances in Ion Channels and Ion Channelopathies
edited by
submission deadline 20 Sep 2023 | 5 articles | Viewed by 6780
Keywords: ion channel; disease; ion channelopathies; signaling; tissues
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Immune Factors, Immune Cells and Inflammatory Diseases
edited by
submission deadline 20 Sep 2023 | 6 articles | Viewed by 6424
Keywords: cytokines; chemokines; leucocytes; lymphocytes; immunity; inflammation
(This special issue belongs to the Section Molecular Immunology)
Molecular Aspects of Cardiometabolic Diseases: From Etiopathogenesis to Potential Therapeutic Targets submission deadline 20 Sep 2023 | 5 articles | Viewed by 5467
Keywords: cardiovascular diseases; obesity; diabetes; and insulin resistance; rare metabolic diseases; chronic renal failure; nonalcoholic fatty liver disease; inflammation; oxidative stress; gasotransmitters; receptors; ion channels; and nuclear factors; transcriptional factors; extracellular vesicles; noncoding RNAs
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Plant Stress-Induced Responses and Tolerance Mechanisms at Biochemical, Cellular, Physiological and Molecular Levels submission deadline 20 Sep 2023 | 7 articles | Viewed by 5374
Keywords: abiotic stresses; drought stress; heavy water stress; temperature stress; plant molecular responses
(This special issue belongs to the Section Molecular Plant Sciences)
Advances on Heart Failure: From Circulating Biomarkers to Clinical Risk
edited by
submission deadline 20 Sep 2023 | 2 articles | Viewed by 5221
Keywords: heart failure; novel biomarkers; heart failure therapy; brain natriuretic peptide; prognosis; cardiac therapeutic target
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Role of Ion Channels in Cardiovascular and Other Human Diseases submission deadline 20 Sep 2023 | 5 articles | Viewed by 4867
Keywords: ion channel; signal transduction; endothelial cell; vascular smooth muscle; vascular remodeling; vascular tone; microcirculation; vascular regeneration; neuronal disorders; kidney disorders; eye disorders; channelopathy
(This special issue belongs to the Section Biochemistry)
New Insights into Synapse Structure and Function
edited by
submission deadline 20 Sep 2023 | 4 articles | Viewed by 4682
Keywords: synaptic structure; synaptic transmission; synaptic function; synaptic plasticity; neurotransmitter release; neutotransmitter receptor
(This special issue belongs to the Section Molecular Neurobiology)
Computational Approaches for the Investigation of Complex Molecular Mechanisms 2.0
edited by
submission deadline 20 Sep 2023 | 4 articles | Viewed by 3991
Keywords: signal transduction; transcriptional regulation; molecular modeling; molecular dynamics; molecular docking; system biology; mathematical modeling; meta-analysis  
(This special issue belongs to the Section Molecular Informatics)
Molecular Aspects of the Neurodegenerative Brain Diseases
edited by
submission deadline 20 Sep 2023 | 4 articles | Viewed by 3478
Keywords: brain-related disorder; neurodegenerative disease; biomolecule cue; biochemical cue; molecular mechanism; ligand– receptor interaction; drug response
(This special issue belongs to the Section Molecular Neurobiology)
Recent Advances of Targeted Drug Delivery and Nanocarriers
edited by Johanna Simon and Michael Fichter
submission deadline 20 Sep 2023 | 4 articles | Viewed by 3062
Keywords: functionalization strategies; site-specific delivery; controlled drug release; nanocarrier design; manufacturing of tailored nanocarriers
(This special issue belongs to the Section Molecular Biology)
Metabolomics in Health and Disease 2.0
edited by
submission deadline 20 Sep 2023 | 3 articles | Viewed by 2938
Keywords: biomarkers; mass spectrometry; NMR; alternative analytical platforms for metabolomics; data processing workflows; computational biomarker discovery; volatile metabolomics; cancer; neurodegenerative diseases; cardiovascular diseases; epidemiology; rare diseases
(This special issue belongs to the Section Biochemistry)
Early-Stage Drug Discovery: Advances and Challenges 2.0
edited by
submission deadline 20 Sep 2023 | 2 articles | Viewed by 2105
Keywords: medicinal chemistry; drug discovery; computer-assisted drug design; drug targets; machine learning; epigenetic targets; in vitro assays; biophysical methods; target engagement studies; multi-targeting compounds; PROTAC
(This special issue belongs to the Section Molecular Pharmacology)
GABA Signaling in Health and Disease in the Nervous System
edited by and Afia Ali
submission deadline 20 Sep 2023 | 3 articles | Viewed by 1566
Keywords: gamma-aminobutyric acid; neurodevelopment; neuronal differentiation; neuronal disorders; neurodegenerative diseases
(This special issue belongs to the Section Molecular Neurobiology)
Nanotechnology: A Powerful Tool in the Scope of Tissue Engineering Domain
edited by and Adriana Lungu
submission deadline 20 Sep 2023 | 1 articles | Viewed by 1309
Keywords: nanotechnology; 3D printing/3D bioprinting; Drug delivery; hydrogels; nanoparticles; organ-on-a-chip; nanotechnology; tissue engineering; hydrogels; nanoparticles; nanocomposites
(This special issue belongs to the Section Molecular Nanoscience)
Drug Repurposing: Emerging Approaches to Drug Discovery
edited by
submission deadline 20 Sep 2023 | 1 articles | Viewed by 1271
Keywords: repurposed drugs; network medicine; systems medicine; drug design; therapeutic strategies; drug repurposing in the era of artificial intelligence; drug repositioning; machine learning
(This special issue belongs to the Section Molecular Informatics)
Structure and Function of Ribosomal Proteins 2023
edited by
submission deadline 20 Sep 2023 | 2 articles | Viewed by 1043
Keywords: ribosomal proteins; particular regions of ribosomal proteins; translation and its regulation; roles of particular ribosomal proteins’ regions in translation; roles of particular ribosomal proteins’ regions in extra-ribosomal functions; mutations in ribosomal proteins and human diseases
(This special issue belongs to the Section Biochemistry)
Tissue Engineering and Cell Therapy: Recent Progress
edited by
submission deadline 20 Sep 2023 | 1 articles | Viewed by 938
Keywords: biomaterials and cell sources for tissue engineering and cell therapy; tissue engineering of substitutes in vitro; functional testing of tissues reconstructed in vitro; extracellular matrix; mechanical characteristics; biological and histological characterization; translational research
(This special issue belongs to the Section Biochemistry)
Recent Advances and Techniques for the Vascularization of Tissue Engineering Constructs submission deadline 20 Sep 2023 | 1 articles | Viewed by 899
Keywords: tissue engineering; vascularization; vasculogenesis; angiogenesis; biomaterials
(This special issue belongs to the Section Molecular Biology)
Advances in Metabolomics and Small Molecules Analysis submission deadline 20 Sep 2023 | 1 articles | Viewed by 845
Keywords: mass spectrometry; metabolomics; chromatography; small molecule identification; biomarkers; toxicology; machine learning; isotope exchange
(This special issue belongs to the Section Biochemistry)
Primary Mitochondrial Diseases and Secondary Mitochondrial Dysfunction: New Insights and Therapies submission deadline 20 Sep 2023 | 1 articles | Viewed by 827
Keywords: mitochondria; mitochondrial DNA; mitochondrial dynamics; mitophagy; mitochondrial toxicity; apoptosis; primary mitochondrial disease; secondary mitochondrial dysfunction; mitochondria-targeted drug discovery
(This special issue belongs to the Section Molecular Biology)
Molecular Aspects of Endometriosis
edited by
submission deadline 20 Sep 2023 | 2 articles | Viewed by 807
Keywords: endometriosis; molecular mechanisms; therapeutic substances; inflammatory; pathology
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Regulation and Targeting of Ferroptosis in Tumor and Beyond
edited by and Jin Xie
submission deadline 20 Sep 2023 | Viewed by 302
Keywords: ferroptosis; iron; tumor survival and cell death; oxidation; drug development; anticancer strategies
(This special issue belongs to the Section Molecular Oncology)
Current Advances in Diagnostic and Therapeutic Approaches for Gastric Cancer submission deadline 20 Sep 2023 | Viewed by 179
Keywords: gastric cancer; non-invasive diagnostic methodologies; biomarkers; artificial intelligence; digital pathology; response to treatment
(This special issue belongs to the Section Molecular Oncology)
Head and Neck Cancer: From Pathophysiology to Novel Therapeutic Approaches
edited by
submission deadline 20 Sep 2023 | Viewed by 141
Keywords: head and neck cancer; pathophysiology; novel therapeutic approaches; prognosis; molecular mechanisms; tailored treatment
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Molecular and Cellular Aspects of Insulin Resistance submission deadline 20 Sep 2023 | Viewed by 119
Keywords: insulin resistance; insulin receptor; IRS; Akt; PI3K; protein phosphorylation; protein dephosphorylation; inflammation; metabolic syndrome; cardiometabolic syndrome; diabetic cardiomyopathy
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
The Role of Genetics and Epigenetics in Major Structural Malformations
edited by
submission deadline 20 Sep 2023 | Viewed by 55
Keywords: birth defect; genetics; medical genetics; gene and cell therapy
(This special issue belongs to the Section Molecular Genetics and Genomics)
Calcium Homeostasis of Cells in Health and Disease submission deadline 25 Sep 2023 | 12 articles | Viewed by 12043 | Submission Open
(This special issue belongs to the Section Biochemistry)
Programmed Cell Death and Oxidative Stress
edited by
submission deadline 25 Sep 2023 | 5 articles | Viewed by 7303 | Submission Open
Keywords: oxidative stress; programmed cell death; cellular stresses; senescence; cytotoxicity; cancer; neurodegenerative disease; inflammatory disease; organelle stress
(This special issue belongs to the Section Biochemistry)
New Advances in Rare Genetic Disorder
edited by
submission deadline 25 Sep 2023 | 4 articles | Viewed by 2609 | Submission Open
Keywords: rare diseases; disease model; diagnostics; therapeutic targets; therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Sepsis and Septic Shock: From Molecular Mechanisms to Novel Therapies
edited by and Michael Adamzik
submission deadline 25 Sep 2023 | 3 articles | Viewed by 2350 | Submission Open
Keywords: sepsis; septic shock; mechanistic insight; epigenetics; immunometabolism; biomarkers; therapy approach; stratification; precision diagnostics
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Characterization of Extracellular Vesicles in Disease
edited by
submission deadline 26 Sep 2023 | Viewed by 171 | Submission Open
Keywords: extracellular vesicle; exosomes; microvesicles; vesicle cargo
(This special issue belongs to the Section Molecular Biology)
Innovative Platforms for Medical, Pharmaceutical and Diagnostic Applications submission deadline 27 Sep 2023 | 1 articles | Viewed by 935 | Submission Open
Keywords: in vitro 3D models; organoids; drug and nutraceutical screening; preclinical imaging; tissue engineering; precision and regenerative medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advanced Therapies and Functional Materials for Wound Healing
edited by
submission deadline 28 Sep 2023 | 8 articles | Viewed by 8728 | Submission Open
Keywords: chronic and acute wounds; wound infection management; angiogenesis; scars and scarless healing; skin repair and regeneration; drug delivery; functional materials; topical therapy; therapeutic mechanisms of action
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in the Study of Cell Cycle
edited by
submission deadline 28 Sep 2023 | 2 articles | Viewed by 6908 | Submission Open
Keywords: cell cycle machinery; cell cycle checkpoint mechanism; DNA damage checkpoint; cell cycle regulation in the developmental stages; meiotic cell cycle regulation; tissue-specific cell cycle regulation
(This special issue belongs to the Section Molecular Biology)
Cellular and Molecular Mechanisms of Plant Responses to Light submission deadline 28 Sep 2023 | 6 articles | Viewed by 5924 | Submission Open
Keywords: celluar mechanism; light; molecular mechanism; plant growth; Plant development; gene expression; primary and secondary metabolites; photomorphogenesis; photoperiod response; stress resistance; nutrient uptake
(This special issue belongs to the Section Molecular Plant Sciences)
Oxidative Stress and Antioxidants in Human Diseases
edited by Lyubov Iljinichna Kolesnikova
submission deadline 28 Sep 2023 | 5 articles | Viewed by 4424 | Submission Open
Keywords: oxidative stress; metabolic stress; diseases; aging; antioxidants; free radical pathology; reactive oxygen species; cellular damage; antioxidant therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
High Value-Added Compounds from Food Wastes and By-Products submission deadline 28 Sep 2023 | 2 articles | Viewed by 2465 | Submission Open
Keywords: by-product characterization; bio-compound valorization; green synthesis; green extraction procedures; mass spectrometry; nutraceuticals
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Functional Properties of Biologically Active Substances as Food Ingredients
edited by
submission deadline 28 Sep 2023 | 2 articles | Viewed by 1132 | Submission Open
Keywords: biologically active compounds; nutritionology; Postramatuc Stress Disoder (PTSD); PTSD susceptability; oxidative stress; anti-diabiteic; anticancer properties and anti-age properties; functionality of foods; metabolic pathways of biologically active compounds
(This special issue belongs to the Section Bioactives and Nutraceuticals)
The Role of Non-coding RNAs Involved in Cardiovascular Diseases and Cellular Communication submission deadline 29 Sep 2023 | 4 articles | Viewed by 4330 | Submission Open
Keywords: ncRNAs; long non-coding RNAs; miRNAs; cardiovascular diseases; cellular communication; exososomes; multivescicular bodies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanisms of Cardiac Development and Disease submission deadline 30 Sep 2023 | 19 articles | Viewed by 26879 | Submission Open
Keywords: cardiac development cardiac repair regeneration cardiac cell-cell interaction fibrosis remodeling molecular mechanisms
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Role of Water in Biological Systems 2.0 submission deadline 30 Sep 2023 | 2 articles | Viewed by 20090 | Submission Open
Keywords: water structure; solvent properties of water; membrane-less organelles; liquid– liquid phase transition; phase separation; aqueous two-phase systems
(This special issue belongs to the Section Molecular Biophysics)
Antimicrobial Biomaterials: Recent Progress
edited by
submission deadline 30 Sep 2023 | 15 articles | Viewed by 19768 | Submission Open
Keywords: antimicrobial agents; chemical modification; polymer engineering; polymer synthesis; surface functionalization; antimicrobial agents immobilization; new drug delivery systems; microbiocidal; infection control
(This special issue belongs to the Section Materials Science)
Innovative Molecular Target and Therapeutic Approaches in Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis (NAFLD/NASH) 3.0 submission deadline 30 Sep 2023 | 14 articles | Viewed by 17432 | Submission Open
Keywords: fatty liver; steatosis; steatohepatitis; inflammation; fibrosis; cytochines; chemokine receptors; insulin sensitizing drugs; farnesoid X receptor agonists; bile acids; oxidative stress; mitochondrial function; peroxisome proliferator-activated receptors (PPARs)
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Mechanism of Cellular Signaling, Dysfunction and Drug Effects on Liver Diseases
edited by
submission deadline 30 Sep 2023 | 11 articles | Viewed by 15702 | Submission Open
Keywords: viral hepatitis; autoimmune liver diseases; alcoholic liver diseaes; metabolic-associated fatty liver; liver cirrhosis; hepatocellular carcinoma; gut– liver axis; leaky gut; portal hypertension
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Pathogenesis of Chronic Inflammatory Skin Diseases in the "Omics" Era submission deadline 30 Sep 2023 | 10 articles | Viewed by 14728 | Submission Open
Keywords: chronic inflammatory skin diseases; cytokines and chemokines network; role of resident and incoming skin cells; genomic; epigenomic; transcriptomic; proteomic and metabolomic analysis; neurohormones; biologic therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Molecular and Cellular Mechanisms of Neurodegenerative Diseases
edited by
submission deadline 30 Sep 2023 | 9 articles | Viewed by 14500 | Submission Open
Keywords: neurodegenerative diseases; Alzheimer’ s disease (AD); Parkinson’ s disease (PD); frontotemporal lobar degeneration (FTLD); amyotrophic lateral sclerosis (ALS); Huntington’ s disease (HD); prion diseases; cellular and molecular mechanisms; omics
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in the Molecular Biology of Lung Disease
edited by
submission deadline 30 Sep 2023 | 9 articles | Viewed by 12766 | Submission Open
Keywords: severe asthma; COPD; lung cancer; pathology; molecular biomarkers; interstitial lung diseases; immunobiology; omics; prognosis; pathogenesis; proteomics; genetics
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances of Plants-Pathogen Interaction 2023
edited by
submission deadline 30 Sep 2023 | 12 articles | Viewed by 12241 | Submission Open
Keywords: host; effection; pathogenicity; pathogen; plant immunity; interactions
(This special issue belongs to the Section Molecular Plant Sciences)
Fundamental and Practical Perspectives in Regenerative Medicine: Proceedings of the V National Congress of Regenerative Medicine (2022) submission deadline 30 Sep 2023 | 14 articles | Viewed by 11489 | Submission Open
Keywords: regenerative medicine; stem cell; gene therapy; cell therapy; tissue engineering
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
COVID-19 Coagulopathy: Advances on Pathophysiology and Therapies submission deadline 30 Sep 2023 | 11 articles | Viewed by 10927 | Submission Open
Keywords: COVID-19; thrombosis; coagulopathy; coagulation factors; vascular inflammation; acute limb ischemia; acute coronary syndrome; stroke; mesenteric ischemia; deep venous thrombosis; pulmonary embolism; cerebral venous sinus thrombosis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
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