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International Journal of Molecular Sciences runs special issues to create collections of papers on specific topics. The aim is to build a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors who are experts in the subject and oversee the editorial process for papers. Papers published in a Special Issue will be collected together on a dedicated page of the journal website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Nano and Micro-Plastics in Aquatic Systems
edited by Antonio Cid-Samamed
submission deadline 30 May 2024 | 1 articles | Viewed by 587 | Submission Open
Keywords: micro/nanoplastics (MNPs); MNPs’ characterization; MNPs’ colloidal behavior; MNPs’ sorption/desorption of other pollutants; MNPs’ aging; MNPs’ degradation
(This special issue belongs to the Section Materials Science)
Ion Channels in the Nervous System
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 427 | Submission Open
Keywords: voltage-gated ion channels; ligand-gated ion channels; neurons; glia cells; electrical activity; molecular structure; molecular pathway
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Research of Hepatitis C Virus Infection
edited by
submission deadline 30 May 2024 | Viewed by 420 | Submission Open
Keywords: HCV; virus replication and pathogenesis; antivirals; virus– cell interaction; vaccine development; hepatocellular carcinoma
(This special issue belongs to the Section Molecular Immunology)
The Angiotensin in Human Health and Diseases
edited by Helmy M. Siragy
submission deadline 30 May 2024 | Viewed by 287 | Submission Open
Keywords: renin– angiotensin– aldosterone system; angiotensin subtype receptors; cardiovascular disease; kidney diseases; stroke; metabolic abnormalities; obesity and adipose tissue; oxidative stress and inflammation; blood pressure and salt sensitivity
(This special issue belongs to the Section Molecular Biology)
Molecular Research in Viral Hepatitis and Liver Cancer
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 272 | Submission Open
Keywords: hepatitis B; hepatitis C; hepatitis D; hepatocellular carcinoma
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Electrochemistry of Metal Nanomaterials
edited by Evangelina Pensa, Miriam C. Rodríguez González and Maria Pilar Carro Reglero
submission deadline 30 May 2024 | Viewed by 256 | Submission Open
Keywords: metal nanomaterials; electrochemistry; electrocatalysis; charge storage capabilities; electron transfer kinetics
(This special issue belongs to the Section Molecular Nanoscience)
Nutrient Sensing in Human Metabolic Diseases: Associated Molecular Mechanisms submission deadline 30 May 2024 | Viewed by 221 | Submission Open
Keywords: nutrition; functional food; bioactive compounds; gene; nutrigenomics; nutrigenetics; metabolomics; proteomics; microbiota; chronic diseases
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Insight into Dentistry and Craniofacial Surgery: Celebrating the 110th Anniversary of Dentistry in Italy
edited by
submission deadline 30 May 2024 | Viewed by 194 | Submission Open
Keywords: dentistry; craniofacial district; technological; oral health; molecular research; materials; restorative dentistry; prosthodontics; oral surgery; implantology; pediatric dentistry; orthodontics; temporomandibular disorder
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Quantitative Identification and Action-Mechanisms of Anti-cancer and Anti-inflammatory Natural Compounds 3.0 submission deadline 30 May 2024 | Viewed by 166 | Submission Open
Keywords: anticancer; anti-inflammatory; natural compounds; efficacy; mechanism of action; molecular target; bioactivity; pharmacokinetics; pharmacodynamics
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Physiology and Pathology of Neurons 2.0
edited by
submission deadline 30 May 2024 | Viewed by 165 | Submission Open
(This special issue belongs to the Section Molecular Neurobiology)
The Role of Primary Cell Line Models in Evolutionary Molecular Physiology
edited by
submission deadline 30 May 2024 | Viewed by 147 | Submission Open
Keywords: cell physiology; fibroblasts; comparative biology; evolution; physiological ecology; vertebrates; primary cell line
(This special issue belongs to the Section Molecular Biology)
Advanced Glycoproteomics Research
edited by
submission deadline 30 May 2024 | Viewed by 140 | Submission Open
Keywords: glycosylation; glycoproteomics; site-specific glycan structures; glycan function; biochemical validation
(This special issue belongs to the Section Biochemistry)
New Trends in Diabetes, Hypertension and Cardiovascular Diseases 2.0 submission deadline 30 May 2024 | Viewed by 132 | Submission Open
Keywords: cardiovascular disease; myocardial infarction; stroke; transient ischaemic attack; hypertension; diabetes mellitus; atherosclerosis; inflammation
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Role of Extracellular Vesicles in Immunology
edited by and Valeria Longo
submission deadline 30 May 2024 | Viewed by 126 | Submission Open
(This special issue belongs to the Section Molecular Immunology)
Molecular Mechanisms Subserving Taste and Olfaction Systems
edited by
submission deadline 30 May 2024 | Viewed by 114 | Submission Open
Keywords: taste; olfaction; gustation; odor; chemoreception; taste bud cells; nutrient sensing; ingestive behavior; olfactory cilia; olfactory receptor neurons; olfactory bulb; gustatory cortex; piriform cortex; sensory development; food learning; neural plasticity; obesity; eating disorders; appetite
(This special issue belongs to the Section Molecular Neurobiology)
The 150th Anniversary of the Discovery of L.A. Ranvier: Specialization and Plasticity of Fiber Types in the Vertebrate Skeletal Muscles submission deadline 30 May 2024 | Viewed by 101 | Submission Open
(This special issue belongs to the Section Molecular Biology)
Molecular Insights into Type 2 Diabetes and Its Complications
edited by
submission deadline 30 May 2024 | Viewed by 81 | Submission Open
Keywords: diabetes; metabolic defects; β -cell function; dietary intervention; physical exercise
(This special issue belongs to the Section Molecular Biology)
Molecular Mechanisms and Therapies of Colorectal Cancer 3.0 submission deadline 30 May 2024 | Viewed by 81 | Submission Open
Keywords: transforming growth factor beta (TGF-β ) signaling; genetic alterations; molecular targeted therapy precision medicine
(This special issue belongs to the Section Molecular Oncology)
Drug Resistance in Cancer: Molecular Mechanisms and Tackling Strategies 2.0
edited by
submission deadline 30 May 2024 | Viewed by 79 | Submission Open
Keywords: apoptosis; cancer; clinical trials; chemotherapy; drug metabolism; drug resistance; drug delivery; heterogeneity; immunotherapy; microenvironment
(This special issue belongs to the Section Molecular Pharmacology)
Programmed Cell Death and Oxidative Stress 2.0
edited by
submission deadline 30 May 2024 | Viewed by 71 | Submission Open
Keywords: oxidative stress; programmed cell death; cellular stresses; senescence; cytotoxicity; cancer; neurodegenerative disease; inflammatory disease; organelle stress
(This special issue belongs to the Section Biochemistry)
Natural Compounds in Cancer Therapy and Prevention 2.0 submission deadline 30 May 2024 | Viewed by 58 | Submission Open
Keywords: cancer therapy cancer prevention; natural compounds; metastasis; immunomodulation; adjuvant therapy; preventive therapy; drug discovery; natural drugs
(This special issue belongs to the Section Molecular Pharmacology)
New Insights in Natural Bioactive Compounds 3.0 submission deadline 30 May 2024 | Viewed by 56 | Submission Open
Keywords: inflammation; cytokines; ROS; oxidative stress; natural products; flavonoids; cannabinoids
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Mechanisms of Plant Biostimulants
edited by and Julietta Moustaka
submission deadline 30 May 2024 | Viewed by 40 | Submission Open
Keywords: biostimulants; abiotic stresses; biotic stresses; plant growth promoter; stress acclimation; oxidative damage; photosynthetic efficiency; ROS; antioxidant mechanisms; redox regulation
(This special issue belongs to the Section Molecular Plant Sciences)
Advance in the Research of Alzheimer’s Disease and Dietary Neuroprotective Agents submission deadline 30 May 2024 | Viewed by 33 | Submission Open
Keywords: neurodegenerative disorders; brain health; brain– gut-microbiome axis; blood– brain barrier assays; anti-inflammatory activity; antichlolinergic activity; antioxidant activity; bioactive phytochemicals; mechanisms of neuroprotection; brain foods; neuroprotection
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Pathology and Treatment of Neuromuscular Disease
edited by Christopher Nelke and Christina B. Schroeter
submission deadline 30 May 2024 | Viewed by 31 | Submission Open
Keywords: complements; myasthenia gravis; neuromuscular diseases; neuromuscular junction; hereditary disorders; amyotrophic lateral sclerosis; personalized treatments
(This special issue belongs to the Section Molecular Neurobiology)
Immune Modulation of Macrophages 2.0
edited by and Yan Chen
submission deadline 30 May 2024 | Viewed by 28 | Submission Open
Keywords: macrophages; treatment; phenotype change; pathway analysis
(This special issue belongs to the Section Molecular Immunology)
Drought Stress Tolerance in Plants in 2024
edited by
submission deadline 30 May 2024 | Viewed by 26 | Submission Open
Keywords: root physiology; drought tolerance; photosynthesis; water deficit stress; shoot– root interaction; salinity; crop plants
(This special issue belongs to the Section Molecular Plant Sciences)
Anti-hypoxia and Oxygenation Agents for Cancer Immunotherapy
edited by Stephen M. Hatfield and Bruce D. Spiess
submission deadline 30 May 2024 | Viewed by 25 | Submission Open
Keywords: oxygenation agents; blood substitutes; immune checkpoint inhibitors; cancer immunotherapies; target tumor hypoxia; hypoxia-targeting prodrugs; perfluorocarbons; injectable oxygen microparticles
(This special issue belongs to the Section Molecular Pharmacology)
Role of Steroids and Triterpenoids in Plant Growth, Development and Stress Response 2.0
edited by
submission deadline 30 May 2024 | Viewed by 25 | Submission Open
Keywords: biosynthesis; chemical defense; plant growth and development; steroids; sterols; stress response; triterpenoids
(This special issue belongs to the Section Molecular Plant Sciences)
Mechanistic Studies of Mitosis in Human Cells
edited by Eleni Petsalaki
submission deadline 30 May 2024 | Viewed by 25 | Submission Open
Keywords: mitosis; cancer; cell biology; spindle checkpoint; abscission; abscission checkpoint; cytokinesis
(This special issue belongs to the Section Biochemistry)
Circadian Biology in Human Health and Disease
edited by Flore Sinturel
submission deadline 30 May 2024 | Viewed by 24 | Submission Open
Keywords: circadian rhythms; metabolism; misalignment; synchronization; molecular clock; internal body clocks; sleep– wake cycle
(This special issue belongs to the Section Molecular Biology)
Epigenomics in Cancer Research: A Comprehensive Approach submission deadline 30 May 2024 | Viewed by 19 | Submission Open
Keywords: epigenomics; DNA methylation; histone post-translational markers; non-coding RNAs; 3D chromatin structure; cancer
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Brain Metastasis 2024
edited by
submission deadline 30 May 2024 | Viewed by 18 | Submission Open
Keywords: brain metastasis; brain microenvironment; pathology; circulating tumor cells; tumor-normal cell crosstalks; new biomarkers and therapies for brain metastasis; cerebral spinal fluid/liquid biopsy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanisms of Primary Graft Dysfunction and Acute Rejection in Solid Organ Transplantation
edited by
submission deadline 30 May 2024 | Viewed by 17 | Submission Open
Keywords: transplant; graft dysfunction; ischemia– reperfusion injury; DAMPs; immune cells; allo-antigens; acute rejection; metabolism; cell death; MHC; PRRs
(This special issue belongs to the Section Molecular Immunology)
Molecular Research on Cardiac Regenerative Medicine
edited by Ken Takahashi
submission deadline 30 May 2024 | Viewed by 17 | Submission Open
Keywords: heart failure; human induced pluripotent stem cells; hiPSCs; 3D bioprinting; regenerative medicine; tissue engineering
(This special issue belongs to the Section Molecular Biology)
Advances on Retinal Diseases 2.0
edited by Minzhong Yu
submission deadline 30 May 2024 | Viewed by 16 | Submission Open
Keywords: retina; optic nerve; ocular disorder; retinal disease; genetic mutation; aging; drug side effects; novel mutations/biomarkers; signaling pathways; spectral domain optical coherence tomography; stem cell; gene therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Dynamics of Redox Metabolism in Plants submission deadline 30 May 2024 | Viewed by 16 | Submission Open
Keywords: plant metabolism; plant stress; post-translational modifications; reactive oxygen/nitrogen/sulfur species; redox regulation; signaling
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Research on Amyloidosis in Pathobiology and Therapy
edited by
submission deadline 30 May 2024 | Viewed by 15 | Submission Open
Keywords: amyloidosis; ATTR; transthyretin; misfolding; molecular mechanisms; molecular therapeutic targets; molecular imaging; SPECT; tracers
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Pathogenetic Factors of Ophthalmological Symptoms in Systemic Diseases submission deadline 30 May 2024 | Viewed by 14 | Submission Open
Keywords: diagnosis; uveitis; keratitis; ocular inflammation; hypersensitivity
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Microbial Biofilms in Host-Immune Responses and Antimicrobial Therapy
edited by Mayri Alejandra Díaz De Rienzo
submission deadline 30 May 2024 | Viewed by 13 | Submission Open
Keywords: biofilms; immune response; antimicrobial resistance; disruption; quorum sensing; host interactions
(This special issue belongs to the Section Molecular Microbiology)
Recent Research on Vitamin D Metabolism in Disease
edited by Arnaud Molin
submission deadline 30 May 2024 | Viewed by 11 | Submission Open
Keywords: vitamin D; vitamin D receptor; vitamin D metabolizing enzyme; vitamin D metabolism; vitamin D regulation; calcium– phosphate homeostasis; cell differenciation; cell proliferation
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Editorial Board Members’ Collection Series: Chemical Molecular Structure, Function and Reactions submission deadline 30 May 2024 | Viewed by 11 | Submission Open
Keywords: chemical molecules; chemical reactions; molecules interations; molecules structure; molecular dynamics
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Molecular Mechanisms and Therapeutic Advances in Brain Metastasis
edited by Malcolm Lim
submission deadline 30 May 2024 | Viewed by 11 | Submission Open
Keywords: brain metastasis; brain microenvironment; neurotransmitters co-option; blood-tumour barrier; cancer drug delivery; targeted radiotherapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular and Electrophysiological Modulation in Cardiac Arrhythmias
edited by
submission deadline 30 May 2024 | Viewed by 10 | Submission Open
Keywords: arrhythmias; cardiac electrophysiology; molecular biology; ion channels; intracellular regulation; intracellular calcium dynamics; trafficking; post-translational modifications; structural alterations; gene expression; animal models; basic; translational and clinical science
(This special issue belongs to the Section Molecular Biology)
New Insight into Cannabinoid Effects 3.0
edited by
submission deadline 30 May 2024 | Viewed by 10 | Submission Open
Keywords: cannabinoids; endogenous cannabinoids; neurodegenerative diseases; cancer; pharmacology
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Lung Cancers: An Update on Molecular Diagnostics and Therapy
edited by
submission deadline 30 May 2024 | Viewed by 10 | Submission Open
Keywords: lung cancer; cancer cachexia; prognosis; anti-lung cancer agents
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Parasite Biology and Host-Parasite Interactions 2.0 submission deadline 30 May 2024 | Viewed by 10 | Submission Open
Keywords: parasite; immunity; immunomodulation; helper T cells; IgA; IgE; eosinophils; mast cells; regulatory T cells; galectin
(This special issue belongs to the Section Molecular Biology)
Targeting Blood Vessels in Cancer and Fibrosis submission deadline 30 May 2024 | Viewed by 9 | Submission Open
Keywords: blood vessels; angiogenesis; fibrosis; fibroblasts; hypoxia; pericytes
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Research on Molecular Dynamics 2.0
edited by and
submission deadline 30 May 2024 | Viewed by 9 | Submission Open
Keywords: molecular dynamics; quantum mechanics/molecular mechanics approaches; conformational change; dynamic changes of intermolecular interactions; protein– ligand interactions; nucleic acid ligand interactions; computational modeling of molecular systems; drug design and delivery; structure– function relationships in proteins; simulation of drug-like molecules and lipid membranes
(This special issue belongs to the Section Molecular Biophysics)
Molecular Research on Prostate Cancer
edited by
submission deadline 30 May 2024 | Viewed by 9 | Submission Open
Keywords: prostate cancer; molecular biology; genomics; biomarkers; signaling pathways; precision medicine; treatment resistance; epigenetics; therapeutic targets
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
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