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Cardiac Diseases: Molecular Mechanisms and Therapeutic Strategies

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".

Deadline for manuscript submissions: 31 October 2024 | Viewed by 190

Special Issue Editor

Guest Editor
Department of Biochemistry and Immunology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Brazil
Interests: cellular electrophysiology

Special Issue Information

Dear Colleagues,

Ion channels, membrane proteins that facilitate the passage of various ions across cell membranes, play a pivotal role in numerous physiological functions, notably neuronal signaling and the contraction of cardiac muscles. The activation kinetics of ion channels usually commence with a stimulus triggering a coordinated conformational change in the channel protein. In the context of cardiac diseases, this process holds significant relevance. The resulting conformational change leads to the opening of a channel pore, selectively allowing ions to traverse the cell membrane. Notably, the molecular behavior of ion channels can be influenced by various agents, including neurotransmitters, hormones, and drugs.

Within the realm of cardiac diseases, understanding the cellular and molecular aspects of these fundamental processes becomes paramount. Cardiac diseases involve intricate research in the field of cardiac cellular electrophysiology. State-of-the-art molecular and biophysical techniques are applied to cardiac myocytes obtained from diverse experimental models to unravel the complexities of heart function. We encourage contributions employing innovative approaches to elucidate molecular mechanisms, thereby enhancing our understanding of the molecular basis of cardiac diseases from a multiscale perspective.

Dr. Jader Santos Cruz
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • electrophysiology
  • cardiac diseases
  • electrical signals
  • electrical remodeling
  • channels dysfunction

Published Papers

This special issue is now open for submission.
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