ijms-logo

Journal Browser

Journal Browser

Advances in Molecular Biology of Pituitary Diseases

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".

Deadline for manuscript submissions: 31 October 2024 | Viewed by 42

Special Issue Editors


E-Mail Website
Guest Editor
Department of Translational Medicine and Surgery, Unit of Endocrinology, Università Cattolica del Sacro Cuore—Fondazione Policlinico “Gemelli” IRCCS, Largo Gemelli 8, I-00168 Rome, Italy
Interests: pituitary; acromegaly; Cushing’s syndrome; hyperprolactinemia; TSH-secreting pituitary adenoma; syndrome of reduced sensitivity to thyroid hormones; thyroid; adrenal gland
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Translational Medicine and Surgery, Unit of Endocrinology, Università Cattolica del Sacro Cuore—Fondazione Policlinico “Gemelli” IRCCS, Largo Gemelli 8, I-00168 Rome, Italy
Interests: pituitary; acromegaly; Cushing’s syndrome; hyperprolactinemia; TSH-secreting pituitary adenoma; syndrome of reduced sensitivity to thyroid hormones; thyroid; adrenal gland
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue aims to present the latest research on the molecular biology of pituitary diseases. Pituitary adenoma is a common disease, accounting for about 10% of the general population, and generally presents as a benign tumor. However, in rare cases, tumors can become malignant and metastasize. Pituitary adenomas are also associated with specific syndromes (e.g., acromegaly, Cushing’s syndrome, prolactinoma, syndrome of inappropriate TSH secretion) due to inappropriate hormone secretion. Continuous advances in molecular biology techniques have improved our understanding of the pathogenesis and biology of these tumors, and this knowledge can be applied to the development of diagnostic methods and treatment options. Interestingly, molecular biology techniques have uncovered the pathophysiological mechanisms of non-neoplastic pituitary diseases, such as thyroid hormone resistance syndrome or inappropriate non-neoplastic TSH secretion. An important topic regarding syndromes of reduced thyroid hormone sensitivity is the discovery of polymorphisms in gene encoding type 2 deiodinase. Finally, genetic analysis can identify mutations in genes encoding transcription factors involved in pituitary development that may be involved in the pathogenesis of pituitary hormone deficiency.

Dr. Rosa Maria Paragliola
Prof. Dr. Salvatore Maria Corsello
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pituitary adenomas
  • pituitary carcinomas
  • hypopituitarism
  • acromegaly
  • somatostatin receptor ligands
  • prolactinoma
  • Cushing’s syndrome
  • TSH-secreting adenomas
  • syndromes of reduced sensitivity to thyroid hormones

Published Papers

This special issue is now open for submission.
Back to TopTop