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Special Issue "Redox Biomarkers in the Evaluation of the Antioxidant Profile In Vitro and In Vivo"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: 30 December 2023 | Viewed by 395

Special Issue Editors

Department of Biochemistry and Biotechnology, University of Thessaly, Viopolis, Mezourlo, 41500 Larissa, Greece
Interests: antioxidant activity; plant phenolics; exercise; functional foods; toxicology; redox nutrition; antioxidant administration
Special Issues, Collections and Topics in MDPI journals
Department of Biochemistry and Biotechnology, University of Thessaly, 41500 Larissa, Greece
Interests: redox biology; free radicals; antioxidants; polyphenols; oxidative stress; toxicology

Special Issue Information

Dear Colleagues,

The approach of using redox biomarkers in the evaluation of the antioxidant profile both in vitro and in vivo has recently resurfaced. Although usually overlooked, recent scientific evidence indicates that redox biomarkers can become a useful tool with great translational potency in the field of redox biology. As defined by Veskoukis et al. in 2019 (10.1016/j.cotox.2018.10.001), a redox biomarker might be an antioxidant molecule modified following interaction with reactive species, the products of the detrimental impact of reactive species on biomolecules, and the reactive species per se. Furthermore, terms such as “oxidant” and “pro-oxidant” seem rather vague today as they have not been fully elucidated. On the same basis, the characterization of a compound as “antioxidant” is not sufficient since this term does not denote exactly the biological role of a given substance. Indeed, it is not clear whether the molecule in question prevents oxidation of biomolecules or repairs the oxidative modifications they have already undergone. To this end, redox biomarkers can putatively offer a valuable service in this area since, when functionally clustered, they might give the appropriate information for the actual role of an antioxidant.

In this Special Issue, we invite researchers to contribute both review papers and original research articles that will approach the issue of using biomarkers in order to evaluate, on one hand, the antioxidant status of nutritional agents in vitro and, on the other hand. the redox status of a wide range of organisms in vivo. Potential topics include but are not limited to the following:

  • Biomarkers used for the evaluation of in vivo antioxidant mechanisms;
  • Biomarkers for assessing the antioxidant activity of plant compounds in vitro;
  • Antioxidant status in disease versus health using redox biomarkers;
  • Evaluation of redox status in aging.

Prof. Dr. Dimitrios Kouretas
Dr. Fotios Tekos
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • antioxidants
  • redox biomarkers
  • redox biology

Published Papers

This special issue is now open for submission.
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