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Nutrients
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Food and Nutrition Research – the Omics Era
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Food and Nutrition Research – the Omics Era

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Public Health".

Deadline for manuscript submissions: closed (30 September 2021) | Viewed by 9279

Special Issue Editors

Prof. Dr. Alejandro Cifuentes

E-Mail Website
Guest Editor
Laboratory of Foodomics, CIAL, National Research Council of Spain (CSIC), Madrid, Spain
Interests: foodomics; metabolomics; molecular mechanisms; neuroprotection; sustainable biomass; advanced chemical characterization
Special Issues, Collections and Topics in MDPI journals
Dr. Alberto Valdés

E-Mail Website
Guest Editor
Laboratory of Foodomics, CIAL, National Research Council of Spain (CSIC), Madrid, Spain
Interests: foodomics; metabolomics; proteomics; transcriptomics; food & health; chemometrics; bioinformatics

Special Issue Information

Dear Colleagues, 

It is our pleasure to announce the Special Issue of Nutrients devoted to “Food and Nutrition Research - The Omics Era”.

This publication will contain both original and review papers by recognized experts in the field concerning various aspects related to advances in food and nutrition research as well as the development and use of omics techniques. The topics covered are: determination/evaluation of nutritional values; characterization of bioactive molecules from food and food by-products with health benefits or toxic effects; phytochemicals, macronutrients, micronutrients and human health; prebiotics and probiotics; nutrigenetics, nutrigenomics and foodomics; nutrition and metabolism; clinical nutrition; metabolomics, proteomics, transcriptomics, genetics, epigenetics and metagenomics; bioinformatics and chemometrics.

We would like to invite you to contribute to this Special Issue by presenting your current studies and results as a research article. Review articles are also welcome provided the topic of the review is discussed with us. The deadline for manuscript submission is September 30th, 2021. Each manuscript should be written and submitted according to the guidelines shown below. The manuscripts will be reviewed according to the standard reviewing procedure.

We are confident that, with your contribution, the Special Issue will be an important document in the field of food, nutrition and omics research. Thank you in advance for your interest and your cooperation.

Sincerely yours,

Prof. Dr. Alejandro Cifuentes
Dr. Alberto Valdés
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Phytochemicals, Macronutrients, Micronutrients and Human Health
  • Prebiotics and Probiotics
  • Nutrigenetics and Nutrigenomics
  • Nutrition and Metabolism
  • Clinical Nutrition
  • Foodomics
  • Metabolomics
  • Proteomics
  • Transcriptomics
  • Genetics and Epigenetics
  • Metagenomics
  • Bioinformatics and chemometrics

Published Papers (3 papers)

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Research

13 pages, 1058 KiB  
Article
Pressurized Liquid Extraction Combined with Enzymatic-Assisted Extraction to Obtain Bioactive Non-Extractable Polyphenols from Sweet Cherry (Prunus avium L.) Pomace
by Gloria Domínguez-Rodríguez, María Concepción García, María Luisa Marina and Merichel Plaza
Nutrients 2021, 13(9), 3242; https://doi.org/10.3390/nu13093242 - 17 Sep 2021
Cited by 6 | Viewed by 2951
Abstract
Sweet cherry generates large amounts of by-products within which pomace can be a source of bioactive phenolic compounds. Commonly, phenolic compounds have been obtained by conventional extraction methodologies. However, a significant fraction, called non-extractable polyphenols (NEPs), stays held in the conventional extraction residues. [...] Read more.
Sweet cherry generates large amounts of by-products within which pomace can be a source of bioactive phenolic compounds. Commonly, phenolic compounds have been obtained by conventional extraction methodologies. However, a significant fraction, called non-extractable polyphenols (NEPs), stays held in the conventional extraction residues. Therefore, in the present work, the release of NEPs from cherry pomace using pressurized liquid extraction (PLE) combined with enzyme-assisted extraction (EAE) using PromodTM enzyme is investigated for the first time. In order to study the influence of temperature, time, and pH on the NEPs extraction, a response surface methodology was carried out. PLE-EAE extracts displayed higher TPC (75 ± 8 mg GAE/100 g sample) as well as, PA content, and antioxidant capacity than the extracts obtained by PLE (with a TPC value of 14 ± 1 mg GAE/100 g sample) under the same extraction conditions, and those obtained by conventional methods (TPC of 8.30 ± 0.05 mg GAE/100 g sample). Thus, PLE-EAE treatment was more selective and sustainable to release NEPs from sweet cherry pomace compared with PLE without EAE treatment. Besides, size-exclusion chromatography profiles showed that PLE-EAE allowed obtaining NEPs with higher molecular weight (>8000 Da) than PLE alone. Full article
(This article belongs to the Special Issue Food and Nutrition Research – the Omics Era)
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11 pages, 5566 KiB  
Article
Synergistic Interaction in the Analgesic-Like Effects of Maqui Berry and Citrus Is Antagonized by Sweeteners
by Vicente Agulló, María Eva González-Trujano, Alberto Hernandez-Leon, Erika Estrada-Camarena, Francisco Pellicer and Cristina García-Viguera
Nutrients 2021, 13(7), 2466; https://doi.org/10.3390/nu13072466 - 19 Jul 2021
Cited by 3 | Viewed by 2756
Abstract
Although physiologically pain has a protective function, in many diseases, it is one of the most prominent symptoms. Today, new trends are focused on finding more natural alternatives to conventional treatments to alleviate it. Thereby, the purpose of this investigation was to obtain [...] Read more.
Although physiologically pain has a protective function, in many diseases, it is one of the most prominent symptoms. Today, new trends are focused on finding more natural alternatives to conventional treatments to alleviate it. Thereby, the purpose of this investigation was to obtain preclinical data of the antinociceptive properties of a lyophilized obtained from a newly designed maqui–citrus beverage alone and added with different sweeteners. To achieve this objective, maqui berry and citrus pharmacological activity were studied separately, as well as the interaction of both ingredients. In addition, due to the controversy generated regarding the intake of sugars, related to different metabolic diseases, the influence of different sweeteners (stevia, sucralose, or sucrose) was studied to determine their possible influence on the bioactive compounds of this product. For the attainment of our goals, a pharmacological evaluation, using the 1% formalin test, a nociceptive pain model in mice, was performed by using a sub-efficacious dosage of Maqui (25 mg/kg, i.p.) alone and combined with citrus, and then compared with the effects obtained in the presence of the different sweeteners. As a result, the antinociceptive response of the maqui was synergized in the presence of citrus in the neurogenic and inflammatory phases of the formalin test. However, this response was partially or totally reduced in the presence of the sweeteners. Our study gives preclinical evidence that a combination of maqui and citrus might exert beneficial actions to relieve pain, whereas the presence of sweeteners could reduce or avoid it. Full article
(This article belongs to the Special Issue Food and Nutrition Research – the Omics Era)
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12 pages, 793 KiB  
Article
Baseline Levels of Vitamin D in a Healthy Population from a Region with High Solar Irradiation
by Alicia García-Dorta, Lillian Medina-Vega, Jacobo Javier Villacampa-Jiménez, Marta Hernández-Díaz, Sagrario Bustabad-Reyes, Enrique González-Dávila and Federico Díaz-González
Nutrients 2021, 13(5), 1647; https://doi.org/10.3390/nu13051647 - 13 May 2021
Cited by 2 | Viewed by 2551
Abstract
The use of vitamin D (VitD) supplements has become widespread in the last decade due not only to the dissociation between the blood levels recommended as “optimal” and those shown by the healthy population but also to its presumed beneficial effects on multiple [...] Read more.
The use of vitamin D (VitD) supplements has become widespread in the last decade due not only to the dissociation between the blood levels recommended as “optimal” and those shown by the healthy population but also to its presumed beneficial effects on multiple disorders. This work evaluated the levels of 25-hydroxyvitamin D (25(OH)D) in a healthy population of European origin living in a region with high solar irradiation. In serum samples from a population-based study conducted in the Canary Islands, levels of 25(OH)D were analyzed. In 876 individuals who had no history of kidney or malabsorption disorders and, who had not been treated with calcium and/or VitD supplementation, the median 25(OH)D level was 26.3 (5th; 95th percentile, 14.3; 45.8) ng/mL. Notably, 65.4% of the population had 25(OH)D blood levels below 30 ng/mL, 23.4% below 20 ng/mL and 6.4% below 15 ng/mL. Based on the lack of evidence supporting causality between 25(OH)D levels below what is recommended as optimal (≥20 ng/mL, or even ≥30 ng/mL) and major skeletal and non-skeletal diseases, and in light of the distribution of the concentration of this vitamin in healthy adults living under optimal conditions of solar irradiation, it seems reasonable to consider 25(OH)D levels below 20 ng/mL and close to 15 ng/mL as adequate for the general population. Full article
(This article belongs to the Special Issue Food and Nutrition Research – the Omics Era)
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