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Neuroprotective Effects of Food Ingredients

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 30 August 2024 | Viewed by 82

Special Issue Editors

Special Issue Information

Dear Colleagues,

Neurodegenerative disorders, such as Parkinson’s and Alzheimer’s disease, are a group of diseases characterized by the progressive loss of neurons from different regions of the brain, causing progressive cognitive impairment, mental deterioration and degeneration of brain tissue. Neurodegenerative disorders share some molecular and cellular characteristics, such as a multifactorial character, related to oxidative stress and free radical formation, neuroinflammation, mitochondrial dysfunction, etc. Presently, there are no therapeutic approaches to cure or even halt the progression of these disorders. On the other hand, external factors related to lifestyle, such as diet, have been postulated as preventive factors in neurodegeneration; in this regard, bioactive food ingredients, such as terpenoids, lipids, phenolic compounds, carotenoids, polysaccharides, peptides, etc., may interfere with different molecular mechanisms related to the progression of such diseases, considering their important associated biological activities. Although huge efforts have been focused on finding new possible therapeutics’ treatments, there is still a long way to go before we completely understand the molecular action of dietary compounds or food ingredients in the prevention of neurodegenerative disorders.

In this Special Issue, we invite researchers to contribute original research articles, as well as review articles, regarding the biological effect of food ingredients and bioactives from agri-food by-products in the prevention of neurodegeneration.

Topics include, but are not limited to, the following:

  • Studies (in vitro, in vivo, animal, pre-clinical, clinical) regarding the effect of food ingredients and bioactive compounds from agri-food by-products in the treatment of neurodegenerative diseases;
  • The role of food ingredients and bioactive compounds from agri-food by-products against oxidative stress in neurodegeneration;
  • The role of food ingredients and bioactive compounds from agri-food by-products against inflammation in neurodegeneration;
  • The development of new food ingredients targeting multifactorial neurodegeneration;
  • Transformation of food ingredients during digestion and its effects on counteracting neurodegeneration;
  • New mechanisms of food ingredients and bioactive compounds from agri-food by-products in crossing the blood–brain barrier (BBB);
  • Omics approaches including foodomics for neuroprotection studies.

Prof. Dr. Elena Ibáñez
Prof. Dr. Alejandro Cifuentes
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

 

Keywords

  • neuroprotection
  • Parkinson
  • Alzheimer
  • bioactive compounds
  • agri-food by-products
  • chemical characterization
  • foodomics
  • metabolomics
  • molecular mechanisms

Published Papers

This special issue is now open for submission.
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