Special Issue "Nutrition and Health for the Aging Population"

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Food Science and Technology".

Deadline for manuscript submissions: closed (30 November 2022) | Viewed by 1579

Special Issue Editor

Johann-Friedrich-Blumenbach-Institute for Zoology and Anthropology, Faculty of Biology and Psychology, Georg-August-University of Göttingen, Am Türmchen 3, 33332 Gütersloh, Germany
Interests: amino acids; arginine; biochemistry; melatonin; mitochondria; metabolism; pharmacology; physiology; supplementation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The demographic transition with the exponentially growing population of elderly people poses a great challenge to science and research. Age-associated metabolic dysfunction resulting in oxidative stress and inflammation is a dominant risk factor for many chronic and degenerative disorders and diseases. The progressive increase in healthcare costs for non-communicable diseases and the increase in morbidity and mortality with advanced age can be attributed to a great extent to the lack of appropriate nutritional support and the accumulative bioenergetic burden supposed upon the target population by the western diet that is usually rich in sugar, fat, and salt, but poor in antioxidants, fibers, and vegan proteins. The availability of bioenergetic resources determines the potential to adapt and survive. Nutrition constitutes a decisive factor in determining health and healthcare costs. The development of supplementation that targets the specific needs of the elderly has been proposed to improve health by supplying sufficient macro and micronutrients. This Special Issue explores current approaches to establish a superior supplementation using whole food, food, and food ingredients of exceptionally high nutrient density. Product development that demonstrates how such supplementation can exert broad positive effects on health in the target population is welcome and we aim to discuss the emerging concepts to improve nutrition and health by supplementation.

Dr. Burkhard Poeggeler
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2300 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • aging
  • amino acids
  • antioxidants
  • fibers
  • food
  • health
  • nutrients
  • product development
  • proteins
  • supplementation

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:


Benincasa hispida Extract Prevents Ovariectomy-Induced Osteoporosis in Female ICR Mice
Appl. Sci. 2023, 13(2), 832; https://doi.org/10.3390/app13020832 - 07 Jan 2023
Cited by 1 | Viewed by 973
With the increase in bone metabolic diseases owing to the aging of the global population, interest in functional food ingredients for improving bone health is increasing. This study aimed to determine the anti-osteoporosis effect of Benincasa hispida extract (BHE, HR1901-W) and 2-furoic acid [...] Read more.
With the increase in bone metabolic diseases owing to the aging of the global population, interest in functional food ingredients for improving bone health is increasing. This study aimed to determine the anti-osteoporosis effect of Benincasa hispida extract (BHE, HR1901-W) and 2-furoic acid in ovariectomy (OVX)-induced osteoporosis in female ICR mice. Thirty-five female ICR mice underwent OVX or sham operation and were randomized into seven groups of five animals as follows: normal, sham, OVX, OVX with genistein (10 mg/kg), 2-furoic acid (20 mg/kg), LBHE (100 mg/kg), and HBHE (200 mg/kg). After an 8-week treatment period, femur and blood samples were collected from mice. Bone density and bone formation markers were significantly recovered in the 2-furoic acid and HBHE supplementation groups compared with those in the OVX group. In addition, bone resorption markers were increased in OVX mice, whereas they were significantly decreased in the OVX + 2-furoic acid and HBHE supplementation groups. This study suggests that BHE supplementation prevents bone resorption and promotes bone formation in OVX mice. These findings indicate that BHE could be used as a promising natural means to prevent OVX-induced osteoporosis and bone metabolic diseases. Full article
(This article belongs to the Special Issue Nutrition and Health for the Aging Population)
Show Figures

Figure 1

Back to TopTop