Special Issue "Tryptophan in Nutrition and Health 3.0"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: 30 November 2023 | Viewed by 1617
Special Issue Editor
Interests: aging; amino acids; antioxidants; inflammaging; melatonin; product development; tryptophan
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Tryptophan is a rate-limiting essential amino acid and thus a building block of life. Tryptophan administration can increase brain serotonin synthesis and release. This, in turn, can improve mood and sleep. Tryptophan is also the precursor of melatonin, neuroactive kynurenines, and niacin. Current research on the physiology and pathophysiology of tryptophan metabolism has revealed the central role of tryptophan and its metabolites as master molecular regulators of neurotransmission and neuromodulation. The ratio of tryptophan to kynurenine is a key parameter determining and reflecting endogenous inflammation and regeneration. Tryptophan metabolites such as melatonin and structurally related microbial agents act as potent antioxidant and bioenergetic agents. This Special Issue will examine the key tryptophan pathways and their molecular targets. The latest developments in tryptophan research are the focus of this article collection, and the studies herein will demonstrate the relevance of tryptophan and its metabolites in nutrition and health. The discovery of a broad range of bioactive compounds derived from tryptophan will enable a better understanding of the unique role of this amino acid in disease prevention and treatment.
Dr. Burkhard Poeggeler
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- antioxidants
- kynurenine
- melatonin
- serotonin
- tryptophan
