Enabling Neuroprotection in Dementia by Antioxidant and Vasoactive Flavonoids
A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Biomedical Engineering".
Deadline for manuscript submissions: 18 January 2025 | Viewed by 235
Special Issue Editor
Interests: aging; amino acids; antioxidants; inflammaging; melatonin; product development; tryptophan
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The process of development and adaptation requires safeguarding by potent antioxidant bioenergetic agents that allow us to maintain health and improve cognition by targeting and enhancing the neurovascular supply of bioenergetic resources for permanent repair, recycling and regeneration of the brain. Recent research on flavonoids demonstrates conclusively that brain health can be improved if neuroinflammation is successfully targeted and resolved. Future studies focusing on a research agenda that aims to target the master regulators of adaptational plasticity and developmental physiology can facilitate the progress of applied sciences by the use of such agents. Bioenergetic stimulation and trophic support result in structural and functional changes that enable the appropriate responses of the brain to any kind of demand and stress. The permanent bioenergetic decline is a hallmark of stress and senescence and can be corrected by sufficient mitochondrial protection that restores the decisive metabolic mechanisms that enable the restoration of cognition and health. The development of flavonoids that allow for neuroprotection has to focus on the metabolic mechanisms and mediators that prevent premature brain aging and disease. By your contributions to the development of applied neurosciences, we aim to demonstrate the perspectives for the application of advanced technologies using flavonoids that have the potential to prevent and cure dementia.
Dr. Burkhard Poeggeler
Guest Editor
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Keywords
- antioxidant
- flavonoids
- aging
- Alzheimer’s disease
- amyloid
- neurovascular coupling
- nutrients
- neurosciences
