Special Issue "The Collagen Connection"
Deadline for manuscript submissions: closed (30 June 2022) | Viewed by 9551
Interests: aging; amino acids; antioxidants; inflammaging; melatonin; product development; tryptophan
Special Issues, Collections and Topics in MDPI journals
Special Issue in Applied Sciences: Nutrition and Health for the Aging Population
Special Issue in International Journal of Molecular Sciences: Targeting Inflammaging and Degeneration by Amino Acids
Special Issue in International Journal of Molecular Sciences: Tryptophan in Nutrition and Health 2.0
Special Issue in Applied Biosciences: Food as Medicine and Medicine as Food
Special Issue in International Journal of Molecular Sciences: Tryptophan in Nutrition and Health 3.0
Special Issue in Brain Sciences: Metabolic Alterations in Neurodegenerative Diseases and Treatment Options
Special Issue in Biomedicines: Antioxidant and Neuroprotective Potential of Natural Compounds: Focus on Alzheimer’s Disease
Special Issue in Applied Sciences: Enabling Neuroprotection in Dementia by Antioxidant and Vasoactive Flavonoids
Special Issue in Applied Biosciences: The Role of Applied Bioscience in Pandemics
Special Issue in Symmetry: Symmetry in Aging and Age-Related Diseases
Special Issue in International Journal of Molecular Sciences: Nutrients and Natural Agents as Drug Leads for Product Development
Collagen is the most abundant protein in the body and this key molecule acts as a decisive element of the skin, connective tissue, joints, interstitium, glymphatic system and cardiovascular system. The endogenous intracellular, intercellular and extracellular matrices as well as the glycocalyx acting as the pericellular matrix are largely formed by collagen and attached matrix elements such as glycoproteins, lipoproteins and glycolipids. Endothelial function and neurovascular coupling are ensured by collagen fibers that enable vasoconstriction and vasodilation. For instance, the globular collagen fibers mediate entrainment by the exposome by translating the night shift and drift of the Schumann resonance into the nocturnal shifting and dipping of blood pressure that enables regenerative slow-wave sleep by synchronizing endogenous temperature-dependent brain activity. Collagen carbamylation or glycosylation and oxidation lead to the formation of defect fibers with misfolded proteins and high molecular collagen fragments. Thus, the continuous repair and regeneration of endogenous collagen is needed. Collagen peptides, vitamins such as vitamin C and trace elements such as zinc can promote endogenous collagen synthesis that declines with age and restore the proper structure and function of these decisive proteins. The constriction and dilation of collagen by water release and absorption brings about a tension of 120 MPa, which is 300 times more than the actin–myosin system can generate in terms of force. Consequently, collagen can develop enormous power and decisively determine the skin, connective tissue and myoskeletal and vascular elasticity and strength.
This Special Issue invites papers on all topics related to collagen and the collagen connection, which are essential elements of all living organisms.
Dr. Burkhard Poeggeler
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- collagen fibers
- collagen peptides
- matrix elements