Dear Colleagues,

The digital approach has revolutionized all the aspects of daily routine; therefore, the investigation of novel materials along with interaction with the surrounding tissues appears to be fundamental.

Zirconia, peek, titanium, and innovative composites could be manufactured in many ways, and in this Special Issue, we aim to collect both research papers and systematic reviews focusing on these novelties.

Moreover, the digital revolution associated with the CAD-CAM workflow has modified how these materials could be manufactured; thus, it would be interesting to evaluate the biological interaction within these new surfaces and the surrounding tissue.

This Special Issue aims to collect original manuscripts related to the novel and innovative evaluation of these new materials along with description of digital workflows and immunohistochemical study to evaluate the interaction with the intraoral tissue.

Dr. Roberto Lo Giudice
Dr. Federica Di Spirito
Guest Editors

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