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Perinatal Lipid Nutrition

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Lipids".

Deadline for manuscript submissions: closed (20 May 2023) | Viewed by 2741

Special Issue Editor


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Guest Editor
Department of Obstetrics and Gynecology, ASST Santi Paolo e Carlo-San Paolo University Hospital, 20142 Milan, Italy
Interests: child nutrition; ultrasound imaging; prenatal diagnosis; fetal growth restriction; gestational diabetes; fetal medicine; obstetric delivery; screening; doppler ultrasonography; reproductive medicine; assisted reproductive technology
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Special Issue Information

Dear Colleagues,

I am pleased to invite you to contribute to the Special Issue entitled “Perinatal Lipid Nutrition”.

Nutritional status and health in pregnancy make up an important area of research, mainly due to the preventive strategies in pathological and development patterns during child and adulthood, according to Baker’s hypothesis on the fetal origins of adults’ diseases.

Appropriate perinatal nutrition might mitigate the impact of risk factors in terms of morbidity in the neonatal period and infancy. Molecular and biological pathways from maternal diet have the potential to cause lifelong phenotypic changes to infants. In particular, the long-chain polyunsaturated n-6 and n-3 fatty acids are essential nutrients, with an impact on membrane biogenesis and the regulation of gene expression via their eicosanoid metabolites.

The aim of this Special Issue is to improve the current knowledge on the impact of perinatal lipid intake on infants’ health. Submissions of original research and review articles that cover gaps in knowledge on the importance of lipid nutrition in perinatal period are encouraged.

Dr. Stefania Triunfo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • perinatal
  • pregnancy
  • fatty acids
  • lipid
  • postnatal

Published Papers (1 paper)

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Review

13 pages, 553 KiB  
Review
Maternal Intake of Polyunsaturated Fatty Acids in Autism Spectrum Etiology and Its Relation to the Gut Microbiota: What Do We Know?
by Elisana Lima Rodrigues, Priscila Silva Figueiredo, Gabriela Marcelino, Rita de Cássia Avellaneda Guimarães, Arnildo Pott, Lidiani Figueiredo Santana, Priscila Aiko Hiane, Valter Aragão do Nascimento, Danielle Bogo and Karine de Cássia Freitas
Nutrients 2023, 15(7), 1551; https://doi.org/10.3390/nu15071551 - 23 Mar 2023
Cited by 1 | Viewed by 2432
Abstract
Maternal food habits and gut microbiota composition have potential effects on fetal neurodevelopment, impacting Autism Spectrum Disorder (ASD). Our research aims to outline the relationship that ingestion of polyunsaturated fatty acids (PUFAs) and the composition of maternal gut microbiota have with the possible [...] Read more.
Maternal food habits and gut microbiota composition have potential effects on fetal neurodevelopment, impacting Autism Spectrum Disorder (ASD). Our research aims to outline the relationship that ingestion of polyunsaturated fatty acids (PUFAs) and the composition of maternal gut microbiota have with the possible development of ASD in offspring. We suggest that genetic factors could be related to the different conversions between unsaturated fatty acids according to sex and, mainly, the impact of the pregnancy diet on the higher or lower risk of neurological impairments. The proportion of the phyla Firmicutes/Bacteroidetes is high with an increased consumption of linoleic acid (LA, n-6 PUFA), which is associated with maternal intestinal dysbiosis and consequently starts the inflammatory process, harming myelinization. In contrast, the consumption of α-linolenic acid (ALA, n-3 PUFA) tends to re-establish the balance of the maternal microbiota with anti-inflammatory action. Moreover, human observational studies showed a strong correlation between the consumption of n-3 PUFA, mainly above 340 g of fish per week, with beneficial effects on infant neurodevelopment. Therefore, we suggest that the proper intake of foods rich in n-3 PUFAs and their supplementation during pregnancy until lactation has an impact on reducing the development of ASD. Controlled studies with n-3 PUFA supplementation are still necessary to verify the ideal dose and the best form of administration. Full article
(This article belongs to the Special Issue Perinatal Lipid Nutrition)
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