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Nutrients
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Maternal Nutrition and Newborn Health: An Old Relationship Endorsed by...
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Maternal Nutrition and Newborn Health: An Old Relationship Endorsed by Recent Evidence

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Pediatric Nutrition".

Deadline for manuscript submissions: closed (5 April 2024) | Viewed by 1753

Special Issue Editors

Prof. Dr. Anna Maria Marconi

E-Mail Website
Guest Editor
Department of Obstetrics and Gynecology, ASST Santi Paolo e Carlo-San Paolo University Hospital, 20142 Milan, Italy
Interests: transplacental passage of nutrients; obesity in pregnancy; gestational diabetes; vegan, vegetarian diet in pregnancy
Special Issues, Collections and Topics in MDPI journals
Dr. Stefania Triunfo

E-Mail Website
Guest Editor
Department of Obstetrics and Gynecology, ASST Santi Paolo e Carlo-San Paolo University Hospital, 20142 Milan, Italy
Interests: child nutrition; ultrasound imaging; prenatal diagnosis; fetal growth restriction; gestational diabetes; fetal medicine; obstetric delivery; screening; doppler ultrasonography; reproductive medicine; assisted reproductive technology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The theory of the developmental origin of health and disease is based on the concept that the origins of lifestyle-related disease are formed at the time of fertilization, embryonic, fetal, and neonatal stages by the interrelation between genes and the environment, including nutrition, stress, and environmental chemicals. Consequently, a suboptimal nutrition in early life, including prenatally as assessed by fetal growth restriction according to the gestational age, increases the susceptibility to the metabolic syndrome, including obesity, diabetes, insulin insensitivity, hypertension, hyperlipidemia, and complications that include coronary heart disease and stroke in adulthood.

To date, a growing body of evidence has been obtained to endorse the original Barker’s hypothesis, ranging from observational and interventional studies focused on the impact of an appropriate female lifestyle in childbearing age, ad hoc supplementation during in vitro fertilization treatments, and target nutrition during pregnancy.

This special issue aims to report and summarize the current knowledge on the relationship between optimal maternal nutrition and feto-neonatal wellbeing as short-term effects and health status in adulthood as long-term effects.

All types of research evidence are welcome to elucidate the impact of safe nutrition in early life.

Prof. Dr. Anna Maria Marconi
Dr. Stefania Triunfo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • maternal nutrition
  • fetal growth
  • newborn health
  • adult health

Published Papers (2 papers)

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Research

14 pages, 410 KiB  
Article
Maternal One-Carbon Nutrient Intake and Risk of Being Overweight or Obese in Their Offspring—A Transgenerational Prospective Cohort Study
by Leonie H. Bogl, Susanne Strohmaier, Frank B. Hu, Walter C. Willett, A. Heather Eliassen, Jaime E. Hart, Qi Sun, Jorge E. Chavarro, Alison E. Field and Eva S. Schernhammer
Nutrients 2024, 16(8), 1210; https://doi.org/10.3390/nu16081210 - 19 Apr 2024
Viewed by 364
Abstract
We aimed to investigate the associations between maternal intake of folate, vitamin B12, B6, B2, methionine, choline, phosphatidylcholine and betaine during the period surrounding pregnancy and offspring weight outcomes from birth to early adulthood. These associations were examined among 2454 mother–child pairs from [...] Read more.
We aimed to investigate the associations between maternal intake of folate, vitamin B12, B6, B2, methionine, choline, phosphatidylcholine and betaine during the period surrounding pregnancy and offspring weight outcomes from birth to early adulthood. These associations were examined among 2454 mother–child pairs from the Nurses’ Health Study II and Growing Up Today Study. Maternal energy-adjusted nutrient intakes were derived from food frequency questionnaires. Birth weight, body size at age 5 and repeated BMI measurements were considered. Overweight/obesity was defined according to the International Obesity Task Force (<18 years) and World Health Organization guidelines (18+ years). Among other estimands, we report relative risks (RRs) for offspring ever being overweight with corresponding 95% confidence intervals across quintiles of dietary factors, with the lowest quintile as the reference. In multivariate-adjusted models, higher maternal intakes of phosphatidylcholine were associated with a higher risk of offspring ever being overweight (RRQ5vsQ1 = 1.16 [1.01–1.33] p-trend: 0.003). The association was stronger among offspring born to mothers with high red meat intake (high red meat RRQ5vsQ1 = 1.50 [1.14–1.98], p-trend: 0.001; low red meat RRQ5vsQ1 = 1.05 [0.87–1.27], p-trend: 0.46; p-interaction = 0.13). Future studies confirming the association between a higher maternal phosphatidylcholine intake during pregnancy and offspring risk of being overweight or obese are needed. Full article
(This article belongs to the Special Issue Maternal Nutrition and Newborn Health: An Old Relationship Endorsed by Recent Evidence)
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9 pages, 248 KiB  
Article
Pacific Islands Families Study: Household Food Security during Pregnancy and Secondary School Educational Achievement
by Leon Iusitini, El-Shadan Tautolo, Lindsay D. Plank and Elaine Rush
Nutrients 2023, 15(19), 4131; https://doi.org/10.3390/nu15194131 - 25 Sep 2023
Viewed by 1059
Abstract
Nutritional environment in early life is a key factor for brain development and function. It is important to understand the relationship between nutrition in early life and academic achievement in adolescence. The birth cohort of the Pacific Islands Families (PIF) study was born [...] Read more.
Nutritional environment in early life is a key factor for brain development and function. It is important to understand the relationship between nutrition in early life and academic achievement in adolescence. The birth cohort of the Pacific Islands Families (PIF) study was born in the year 2000. When their child was six weeks old, mothers were asked questions concerning food security over the past year. Two binary measures of food security were derived as previously used in PIF and also by the Ministry of Health (MOH). In 2020, records of academic achievement from the National Certificate of Educational Achievement (NCEA) for 649 (317 female, 332 male) cohort members showed progressive achievement at levels 1, 2, and 3 of NCEA and allowed University Entrance (UE) to be assessed. The prevalence of food insecurity was not different for sex but high at 29% and 42% using the PIF and MOH definitions of food insecurity, respectively. More females (27%) than males (18%) achieved UE as their highest qualification, and more males (40%) than females (31%) achieved NCEA levels 1 or 2 as their highest qualification. UE was achieved by 25% of those born into food-secure households and 17% from food-insecure households. Logistic regression demonstrated that the odds of achieving UE were 1.8-fold (95% CI 1.2, 2.6, p = 0.003) higher in females than males and, independently, 1.6-fold (95% CI 1.1, 2.5 p = 0.026) higher if the household was food secure. This work emphasises the importance of maternal and early-life food security for subsequent academic achievement and the well-being of future generations. Full article
(This article belongs to the Special Issue Maternal Nutrition and Newborn Health: An Old Relationship Endorsed by Recent Evidence)
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