Compulsive Eating, Anorexia Nervosa and Obesity: From Prevention to Treatment

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".

Deadline for manuscript submissions: 5 August 2024 | Viewed by 2181

Special Issue Editors


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Guest Editor
Department of Biomedical Sciences, Division of Neuroscience and Clinical Pharmacology, University of Cagliari, 09042 Monserrato, Italy
Interests: psychiatric disorders; eating disorders; addiction; dopaminergic system; endocannabinoid system; behavioral neuroscience; eating behavior; animal models of eating disorders
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Guest Editor
Laboratory of Cellular and Molecular Pharmacology, Section of Neurosciences, University of Cagliari, 09042 Monserrato, Italy
Interests: cell signaling; apoptosis; neurotrophins; cytokines; neuroscience
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Biomedical Sciences, Division of Neuroscience and Clinical Pharmacology, University of Cagliari, 09042 Monserrato, Italy
Interests: eating disorders; psychiatric disorders; addiction; endocannabinoid system; behavioral neuroscience; animal models of eating disorders
Special Issues, Collections and Topics in MDPI journals

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Co-Guest Editor
Department of Pharmacology, Physiology and Biophysics, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA
Interests: eating disorders; animal models of eating disorders; behavioral neuroscience; psychiatric disorders; neurodegenerative disorders

Special Issue Information

Dear Colleagues,

In recent years, a growing number of people are dealing with eating disorders in their various, diversified, and complex forms, including anorexia nervosa, binge eating disorders, and overweight and obesity. Moreover, eating disorders and obesity have assumed the entity of a real social and economic emergency due to medical complications and associated psychiatric comorbidities. Of note, eating disorders are nowadays among the deadliest mental illnesses worldwide.

Research in this field has increased exponentially and yielded to a detailed understanding of biological and psychological factors associated with eating disorders and obesity. However, the complex etiology of the maladaptive eating habits that underlie the onset and progression of these disorders remains elusive, hindering the identification of effective therapeutic approaches.

This Special Issue entitled “Compulsive Eating, Anorexia Nervosa and Obesity: From Prevention to Treatment” welcomes original research papers and up-to-date reviews (including systematic reviews and meta-analyses), ranging from preclinical to human studies, designed to explore potential neurobiological mechanisms as well as preventive interventions and behavioral or pharmacological treatments. We invite authors to submit their works and contribute to this research topic of clinically relevant considerable value.

Prof. Dr. Paola Fadda
Dr. Simona Dedoni
Dr. Maria Scherma
Dr. Roberto Collu
Guest Editors

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Keywords

  • anorexia nervosa
  • binge eating disorder
  • bulimia nervosa
  • obesity
  • compulsive eating

Published Papers (2 papers)

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Research

12 pages, 279 KiB  
Article
Cognitive Impulsivity in Anorexia Nervosa in Correlation with Eating and Obsessive Symptoms: A Comparison with Healthy Controls
by Francesco Bevione, Matteo Martini, Federica Toppino, Paola Longo, Giovanni Abbate-Daga, Annalisa Brustolin and Matteo Panero
Nutrients 2024, 16(8), 1156; https://doi.org/10.3390/nu16081156 - 13 Apr 2024
Viewed by 432
Abstract
Impulsivity in eating disorders (ED) has been historically focused on bingeing–purging symptoms, evidencing lower levels in restricting subtypes. In the recent literature, obsessive–compulsive disorder (OCD) has been described as characterized by high cognitive impulsivity. This specific impulsivity factor has been rarely studied in [...] Read more.
Impulsivity in eating disorders (ED) has been historically focused on bingeing–purging symptoms, evidencing lower levels in restricting subtypes. In the recent literature, obsessive–compulsive disorder (OCD) has been described as characterized by high cognitive impulsivity. This specific impulsivity factor has been rarely studied in anorexia nervosa (AN). In this study, 53 inpatients with anorexia nervosa and 59 healthy controls completed the following questionnaires: the Barratt Impulsiveness Scale (BIS-11), the Obsessive–Compulsive Inventory (OCI), the Eating Disorders Inventory—2 (EDI–2), the State–Trait Anxiety Inventory (STAI), and the Beck Depression Inventory (BDI). AN individuals showed significantly increased levels of cognitive instability but no difference in global score and other subscales of impulsivity compared to the healthy controls. Among AN individuals, cognitive instability emerged as being associated with the global score and obsession subscale of the OCI. It was also significantly associated with interoceptive awareness and impulse regulation. Cognitive instability was the main predictor of obsessive thoughts and behaviors in AN. Our study supports the hypothesis of AN as being characterized by high cognitive instability and adds the result that the cognitive domain of impulsivity may be associated with the presence of obsessive symptoms, specifically obsessive thoughts. Full article
16 pages, 732 KiB  
Article
Chrono-Nutritional Patterns, Medical Comorbidities, and Psychological Status in Patients with Severe Obesity
by Silvia Bettini, Sami Schiff, Enrico Carraro, Chiara Callegari, Beatrice Gusella, Giulia Maria Pontesilli, Matteo D’Angelo, Valeria Baldan, Alessandra Zattarin, Giulia Romanelli, Paolo Angeli, Paolo Girardi, Paolo Spinella, Roberto Vettor and Luca Busetto
Nutrients 2023, 15(23), 5003; https://doi.org/10.3390/nu15235003 - 03 Dec 2023
Viewed by 1378
Abstract
Chrono-nutrition studies dietary habits and their role in the onset of metabolic diseases. The aim of this study is to describe chrono-nutritional patterns based on the analysis of the eating habits of patients with severe obesity during the 24-h cycle and investigate a [...] Read more.
Chrono-nutrition studies dietary habits and their role in the onset of metabolic diseases. The aim of this study is to describe chrono-nutritional patterns based on the analysis of the eating habits of patients with severe obesity during the 24-h cycle and investigate a possible relationship between these profiles, the comorbidities, and the psychological status. From the overall evaluation of the chrono-nutritional profiles of 173 patients with severe obesity, four predominant eating patterns were obtained with a refined statistical model. A regression analysis was performed to determine the relationship between chrono-nutritional patterns, medical comorbidities, and psychological status. Profile 1 was the most frequent (46.2%) and characterised by the regular presence of the three main meals. The distribution of the chrono-nutritional profiles did not vary with BMI. Chrono-nutritional profiles affected predominantly psychological variables, with lower performances among chrono-nutritional profiles 3 (to eat during all the 24-h, with nibbling and snacking also during the night) and 4 (like the fourth but without night-eating). This finding could be useful in the assessment and treatment of patients with obesity, allowing the identification of patients with a higher probability of suffering from a psychopathological condition simply by knowing the patients’ dietary profiles. Full article
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