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Nutrients
Special Issues
Compulsive Eating, Anorexia Nervosa and Obesity: From Prevention to Treatment
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Compulsive Eating, Anorexia Nervosa and Obesity: From Prevention to Treatment

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".

Deadline for manuscript submissions: 5 August 2024 | Viewed by 2452

Special Issue Editors

Prof. Dr. Paola Fadda

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Guest Editor
Department of Biomedical Sciences, Division of Neuroscience and Clinical Pharmacology, University of Cagliari, 09042 Monserrato, Italy
Interests: psychiatric disorders; eating disorders; addiction; dopaminergic system; endocannabinoid system; behavioral neuroscience; eating behavior; animal models of eating disorders
Special Issues, Collections and Topics in MDPI journals
Dr. Simona Dedoni

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Guest Editor
Laboratory of Cellular and Molecular Pharmacology, Section of Neurosciences, University of Cagliari, 09042 Monserrato, Italy
Interests: cell signaling; apoptosis; neurotrophins; cytokines; neuroscience
Special Issues, Collections and Topics in MDPI journals
Dr. Maria Scherma

E-Mail Website
Guest Editor
Department of Biomedical Sciences, Division of Neuroscience and Clinical Pharmacology, University of Cagliari, 09042 Monserrato, Italy
Interests: eating disorders; psychiatric disorders; addiction; endocannabinoid system; behavioral neuroscience; animal models of eating disorders
Special Issues, Collections and Topics in MDPI journals
Dr. Roberto Collu

E-Mail Website
Co-Guest Editor
Department of Pharmacology, Physiology and Biophysics, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA
Interests: eating disorders; animal models of eating disorders; behavioral neuroscience; psychiatric disorders; neurodegenerative disorders

Special Issue Information

Dear Colleagues,

In recent years, a growing number of people are dealing with eating disorders in their various, diversified, and complex forms, including anorexia nervosa, binge eating disorders, and overweight and obesity. Moreover, eating disorders and obesity have assumed the entity of a real social and economic emergency due to medical complications and associated psychiatric comorbidities. Of note, eating disorders are nowadays among the deadliest mental illnesses worldwide.

Research in this field has increased exponentially and yielded to a detailed understanding of biological and psychological factors associated with eating disorders and obesity. However, the complex etiology of the maladaptive eating habits that underlie the onset and progression of these disorders remains elusive, hindering the identification of effective therapeutic approaches.

This Special Issue entitled “Compulsive Eating, Anorexia Nervosa and Obesity: From Prevention to Treatment” welcomes original research papers and up-to-date reviews (including systematic reviews and meta-analyses), ranging from preclinical to human studies, designed to explore potential neurobiological mechanisms as well as preventive interventions and behavioral or pharmacological treatments. We invite authors to submit their works and contribute to this research topic of clinically relevant considerable value.

Prof. Dr. Paola Fadda
Dr. Simona Dedoni
Dr. Maria Scherma
Dr. Roberto Collu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • anorexia nervosa
  • binge eating disorder
  • bulimia nervosa
  • obesity
  • compulsive eating

Published Papers (3 papers)

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Research

15 pages, 1373 KiB  
Article
Increased Depressive-like, Anxiety-like, and Perseverative-like Behavior in Binge Eating Model in Juvenile Rats
by Alma Delia Genis-Mendoza, Isela Esther Juárez-Rojop, Yudy Merady Escobar-Chan, Carlos Alfonso Tovilla-Zárate, María Lilia López-Narváez, Humberto Nicolini and Thelma Beatriz González-Castro
Nutrients 2024, 16(9), 1275; https://doi.org/10.3390/nu16091275 - 25 Apr 2024
Viewed by 224
Abstract
The aim of the present study was to evaluate depressive-like, anxiety-like, and perseverative-like behaviors in a binge eating model. Juvenile Wistar rats, using the binge eating model, were compared to caloric restriction, induced stress, and control groups. Rats of the induced stress group [...] Read more.
The aim of the present study was to evaluate depressive-like, anxiety-like, and perseverative-like behaviors in a binge eating model. Juvenile Wistar rats, using the binge eating model, were compared to caloric restriction, induced stress, and control groups. Rats of the induced stress group presented binge-like behaviors in standard food intake in the second cycle of the experiment when compared to the caloric restriction group and the binge eating model group. Depressive-like behavior was observed in the binge eating model group with longer immobility time (p < 0.001) and less swim time (p < 0.001) in comparison to the control group. Anxiety-like behavior was observed by shorter duration of burying latency in the binge eating model group when compared to the induced stress group (p = 0.04) and a longer duration of burying time when compared to the control group (p = 0.02). We observed perseverative-like behavior by the binge model group, who made more entries to the new arm (p = 0.0004) and spent a longer time in the new arm when compared to the control group (p = 0.0001). Our results show differences in behaviors between the groups of rats studied. These results suggest that calorie restriction–refeeding, along with stress, may lead to depressive-like, anxiety-like, and perseverative-like behavioral changes in male Wistar rats. Full article
(This article belongs to the Special Issue Compulsive Eating, Anorexia Nervosa and Obesity: From Prevention to Treatment)
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12 pages, 279 KiB  
Article
Cognitive Impulsivity in Anorexia Nervosa in Correlation with Eating and Obsessive Symptoms: A Comparison with Healthy Controls
by Francesco Bevione, Matteo Martini, Federica Toppino, Paola Longo, Giovanni Abbate-Daga, Annalisa Brustolin and Matteo Panero
Nutrients 2024, 16(8), 1156; https://doi.org/10.3390/nu16081156 - 13 Apr 2024
Viewed by 459
Abstract
Impulsivity in eating disorders (ED) has been historically focused on bingeing–purging symptoms, evidencing lower levels in restricting subtypes. In the recent literature, obsessive–compulsive disorder (OCD) has been described as characterized by high cognitive impulsivity. This specific impulsivity factor has been rarely studied in [...] Read more.
Impulsivity in eating disorders (ED) has been historically focused on bingeing–purging symptoms, evidencing lower levels in restricting subtypes. In the recent literature, obsessive–compulsive disorder (OCD) has been described as characterized by high cognitive impulsivity. This specific impulsivity factor has been rarely studied in anorexia nervosa (AN). In this study, 53 inpatients with anorexia nervosa and 59 healthy controls completed the following questionnaires: the Barratt Impulsiveness Scale (BIS-11), the Obsessive–Compulsive Inventory (OCI), the Eating Disorders Inventory—2 (EDI–2), the State–Trait Anxiety Inventory (STAI), and the Beck Depression Inventory (BDI). AN individuals showed significantly increased levels of cognitive instability but no difference in global score and other subscales of impulsivity compared to the healthy controls. Among AN individuals, cognitive instability emerged as being associated with the global score and obsession subscale of the OCI. It was also significantly associated with interoceptive awareness and impulse regulation. Cognitive instability was the main predictor of obsessive thoughts and behaviors in AN. Our study supports the hypothesis of AN as being characterized by high cognitive instability and adds the result that the cognitive domain of impulsivity may be associated with the presence of obsessive symptoms, specifically obsessive thoughts. Full article
(This article belongs to the Special Issue Compulsive Eating, Anorexia Nervosa and Obesity: From Prevention to Treatment)
16 pages, 732 KiB  
Article
Chrono-Nutritional Patterns, Medical Comorbidities, and Psychological Status in Patients with Severe Obesity
by Silvia Bettini, Sami Schiff, Enrico Carraro, Chiara Callegari, Beatrice Gusella, Giulia Maria Pontesilli, Matteo D’Angelo, Valeria Baldan, Alessandra Zattarin, Giulia Romanelli, Paolo Angeli, Paolo Girardi, Paolo Spinella, Roberto Vettor and Luca Busetto
Nutrients 2023, 15(23), 5003; https://doi.org/10.3390/nu15235003 - 03 Dec 2023
Viewed by 1392
Abstract
Chrono-nutrition studies dietary habits and their role in the onset of metabolic diseases. The aim of this study is to describe chrono-nutritional patterns based on the analysis of the eating habits of patients with severe obesity during the 24-h cycle and investigate a [...] Read more.
Chrono-nutrition studies dietary habits and their role in the onset of metabolic diseases. The aim of this study is to describe chrono-nutritional patterns based on the analysis of the eating habits of patients with severe obesity during the 24-h cycle and investigate a possible relationship between these profiles, the comorbidities, and the psychological status. From the overall evaluation of the chrono-nutritional profiles of 173 patients with severe obesity, four predominant eating patterns were obtained with a refined statistical model. A regression analysis was performed to determine the relationship between chrono-nutritional patterns, medical comorbidities, and psychological status. Profile 1 was the most frequent (46.2%) and characterised by the regular presence of the three main meals. The distribution of the chrono-nutritional profiles did not vary with BMI. Chrono-nutritional profiles affected predominantly psychological variables, with lower performances among chrono-nutritional profiles 3 (to eat during all the 24-h, with nibbling and snacking also during the night) and 4 (like the fourth but without night-eating). This finding could be useful in the assessment and treatment of patients with obesity, allowing the identification of patients with a higher probability of suffering from a psychopathological condition simply by knowing the patients’ dietary profiles. Full article
(This article belongs to the Special Issue Compulsive Eating, Anorexia Nervosa and Obesity: From Prevention to Treatment)
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