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Nutrients
Special Issues
Nutrition for Muscle Repair and Recovery
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Nutrition for Muscle Repair and Recovery

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Sports Nutrition".

Deadline for manuscript submissions: 16 June 2024 | Viewed by 4161

Special Issue Editor

Dr. David Russ

E-Mail Website
Guest Editor
School of Physical Therapy & Rehabilitation Sciences, University of South Florida, Tampa, FL, USA
Interests: neuromuscular physiology; fatigue; aging; neuromuscular electrical stimulation; exercise; physical rehabilitation

Special Issue Information

Dear Colleagues,

As a tissue subject to mechanical and metabolic stress, skeletal muscle can utilize several endogenous processes to promote tissue repair and recovery. Nevertheless, there is substantial interest in enhancing or augmenting these processes to speed repair and recovery in order to regain function after illness or injury, mitigate ongoing disease processes, optimize human performance and promote regular physical activity. Nutritional interventions, both dietary modification and specific supplements, carry fewer concerns related to side effects and polypharmacy, and may be translated into clinical use more rapidly than drugs. Accordingly, there is great interest in pre-clinical and translational studies, as well as clinical trials of nutritional interventions that target muscle repair and recovery.

The purpose of this Special Issue is to present current studies on the effects of nutritional interventions on mechanisms and outcomes related to the restoration of muscle function under conditions of injury, aging, and/or disease. Original research in both human and animal models, including preliminary studies/short reports, as well as narrated and systematic reviews and meta-analyses are welcome. Papers presenting data at the molecular, cellular, tissue/organ, and organismal levels will be considered.

Dr. David Russ
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • skeletal muscle
  • myogenesis
  • sarcopenia
  • atrophy
  • fatigue
  • physical performance
  • injury
  • metabolisms
  • micronutrients
  • macronutrients

Published Papers (2 papers)

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Research

11 pages, 1139 KiB  
Article
The Effect of Prior Creatine Intake for 28 Days on Accelerated Recovery from Exercise-Induced Muscle Damage: A Double-Blind, Randomized, Placebo-Controlled Trial
by Shota Yamaguchi, Takayuki Inami, Hiroyuki Ishida, Akihisa Morito, Satoshi Yamada, Naoya Nagata and Mitsuyoshi Murayama
Nutrients 2024, 16(6), 896; https://doi.org/10.3390/nu16060896 - 20 Mar 2024
Viewed by 2425
Abstract
Despite the known beneficial effects of creatine in treating exercise-induced muscle damage (EIMD), its effectiveness remains unclear. This study investigates the recovery effect of creatine monohydrate (CrM) on EIMD. Twenty healthy men (21–36 years) were subjected to stratified, randomized, double-blind assignments. The creatine [...] Read more.
Despite the known beneficial effects of creatine in treating exercise-induced muscle damage (EIMD), its effectiveness remains unclear. This study investigates the recovery effect of creatine monohydrate (CrM) on EIMD. Twenty healthy men (21–36 years) were subjected to stratified, randomized, double-blind assignments. The creatine (CRE) and placebo (PLA) groups ingested creatine and crystalline cellulose, respectively, for 28 days. They subsequently performed dumbbell exercises while emphasizing eccentric contraction of the elbow flexors. The EIMD was evaluated before and after exercise. The range of motion was significantly higher in the CRE group than in the PLA group 24 h (h) post exercise. A similar difference was detected in maximum voluntary contraction at 0, 48, 96, and 168 h post exercise (p = 0.017–0.047). The upper arm circumference was significantly lower in the CRE group than in the PLA group at 48, 72, 96, and 168 h post exercise (p = 0.002–0.030). Similar variation was observed in the shear modulus of the biceps brachii muscle at 96 and 168 h post exercise (p = 0.003–0.021) and in muscle fatigue at 0 and 168 h post exercise (p = 0.012–0.032). These findings demonstrate CrM-mediated accelerated recovery from EIMD, suggesting that CrM is an effective supplement for EIMD recovery. Full article
(This article belongs to the Special Issue Nutrition for Muscle Repair and Recovery)
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22 pages, 10968 KiB  
Article
Glycine and N-Acetylcysteine (GlyNAC) Combined with Body Weight Support Treadmill Training Improved Spinal Cord and Skeletal Muscle Structure and Function in Rats with Spinal Cord Injury
by Xin Xu, Hua-Yong Du, Zuliyaer Talifu, Chun-Jia Zhang, Ze-Hui Li, Wu-Bo Liu, Yi-Xiong Liang, Xu-Luan Xu, Jin-Ming Zhang, De-Gang Yang, Feng Gao, Liang-Jie Du, Yan Yu, Ying-Li Jing and Jian-Jun Li
Nutrients 2023, 15(21), 4578; https://doi.org/10.3390/nu15214578 - 28 Oct 2023
Viewed by 1427
Abstract
Skeletal muscle atrophy is a frequent complication after spinal cord injury (SCI) and can influence the recovery of motor function and metabolism in affected patients. Delaying skeletal muscle atrophy can promote functional recovery in SCI rats. In the present study, we investigated whether [...] Read more.
Skeletal muscle atrophy is a frequent complication after spinal cord injury (SCI) and can influence the recovery of motor function and metabolism in affected patients. Delaying skeletal muscle atrophy can promote functional recovery in SCI rats. In the present study, we investigated whether a combination of body weight support treadmill training (BWSTT) and glycine and N-acetylcysteine (GlyNAC) could exert neuroprotective effects, promote motor function recovery, and delay skeletal muscle atrophy in rats with SCI, and we assessed the therapeutic effects of the double intervention from both a structural and functional viewpoint. We found that, after SCI, rats given GlyNAC alone showed an improvement in Basso–Beattie–Bresnahan (BBB) scores, gait symmetry, and results in the open field test, indicative of improved motor function, while GlyNAC combined with BWSTT was more effective than either treatment alone at ameliorating voluntary motor function in injured rats. Meanwhile, the results of the skeletal muscle myofiber cross-sectional area (CSA), hindlimb grip strength, and acetylcholinesterase (AChE) immunostaining analysis demonstrated that GlyNAC improved the structure and function of the skeletal muscle in rats with SCI and delayed the atrophication of skeletal muscle. Full article
(This article belongs to the Special Issue Nutrition for Muscle Repair and Recovery)
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