Special Issue "Modern Management and Treatment of Diabetes—Celebrating the 100th Anniversary of the First Diabetic Patient Who Received Insulin"
Deadline for manuscript submissions: closed (30 November 2022) | Viewed by 17872
Interests: cardiovascular risk; lipids; diabetes; prevention; therapy; metabolic syndrome; metabolism; lipoproteins; incretins; nutraceuticals
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Interests: thyroid; bone metabolism; osteoporosis; adrenals; diabetes
Special Issues, Collections and Topics in MDPI journals
Diabetes mellitus (DM) is a scourge of our time, with an ever-increasing trend in all countries. The International Diabetes Federation (IDF) estimates that the total number of people with type 2 DM (DM2) is 425 million worldwide, with the ominous prospect of reaching 693 million in 2045. The upward trend of the disease is due in large part to the modern way of life, with aggravating factors being obesity, lack of exercise and chronic stress. Type 1 DM (DM1) shows an equally increasing trend (over 3%) every year. An extremely worrying phenomenon is the increasing incidence of obesity and DM2 in children and adolescents.
However, the improvement of therapeutic approaches and the prevention of DM in recent years is promising, having catalyzed the mitigation of risk and the management of acute and chronic complications. As a matter of fact, looking at the risk and causes of death in the United States over the past 20 years, despite the increase in DM2 (which tripled), there was no corresponding increase in deaths, mainly due to a reduction in cardiovascular complications (mainly heart attacks/strokes).
DM is a complex systemic disease and affects not only glucose metabolism, but the whole of cellular metabolism in all tissues without exception. In the course of the disease, comorbidities emerge from all systems (cardiovascular, nervous, digestive, kidney, skin, even from the mental sphere), as a result of chronic hyperglycemia–dyslipidemia and chronic complications. For this reason optimal metabolic regulation is considered imperative. The introduction of pioneering drugs, the combinations of which offer flexibility and effectiveness in treatment options, has made a decisive contribution in achieving this goal. At the same time, the rapid development of technology, and its application in the field of DM (new generation insulin pumps, artificial pancreas, modern devices for measuring blood glucose, devices for continuous glucose monitoring), has augmented the capability of "tightening" glycemic regulation.
The aim of the present Special Issue is to harmoniously combine the latest scientific data with clinical practice, in an effort to cover the full range of pathophysiology, prevention, treatment and monitoring of DM and its complications. This issue has coincided with an anniversary milestone in DM: the 100th anniversary of the discovery of insulin, the hormone that has given life to millions of people around the world.
With this vision, we invite you to contribute to this Special Issue of Medicina.
Dr. Manfredi Rizzo
Dr. Ioannis Ilias
Manuscript Submission Information
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- diabetes complications
- gestational diabetes mellitus