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|1920||The inaugural issue of the Lithuanian-language journal Medicina (Kaunas, Lithuania) was released. Medicina was published as a monthly journal.|
|1923||The abstracts of all articles were published in German.|
|1941–1944||As a result of political changes, Medicina was renamed twice within this period (L.T.S.R. Medicina and Lietuviškoji Medicina).|
|1944||Publication of the journal was suspended until the re-establishment of Lithuanian independence in 1990.|
|1989||The re-established Lithuanian Medical Association decided to resume the publication of Medicina.|
|1990||Medicina published its first issue after its 46-year break.|
|2001||Under a tripartite agreement among Kaunas University of Medicine, Lithuanian Medical Association and Vilnius University, the journal was reorganized.
Medicina became an open access journal.
|2002||Medicina became the first Lithuanian scientific journal to be indexed in Index Medicus and MEDLINE.|
|2009||Medicina received its first Impact Factor (0.506).|
|2012||From this year onward, all articles in Medicina are published in English only.|
|2014||Elsevier became the publisher of Medicina. The journal adopted a bimonthly publication schedule.|
|2018||Publication of Medicina was transferred to MDPI.
Medicina adopted a monthly publication schedule.
In June, Medicina launched its first Special Issue.
|2020||Medicina established the following sections:
Medicina published its 1,000th paper.
|2021||Medicina received the new Impact Factor (2.430), ranked 80/196 (Q2) in "Medicine, General & Internal category"; CiteScore (2020) for Medicina increased to 1.7.|
|2022||Medicina established the following section:
|1920–1922||Editor-in-Chief: Dr. Juozas Žemgulys|
|1922–1944||Editor-in-Chief: Dr. Jonas Staugaitis|
|1990–2001||Editor-in-Chief: Prof. Dr. Zigmantas Satkevičius|
|2001–2013||Editor-in-Chief: Prof. Habil. Dr. Vilius Grabauskas|
|2013–present||Editor-in-Chief: Prof. Dr. Edgaras Stankevicius|
|2022–present||Section Editor-in-Chief: Prof. Dr. Olaf Dammann for the section on Health Humanities|