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New Insights into Nutraceuticals in the Prevention of Metabolic Syndrome
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New Insights into Nutraceuticals in the Prevention of Metabolic Syndrome

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Nutraceuticals, Functional Foods, and Novel Foods".

Deadline for manuscript submissions: 31 July 2024 | Viewed by 3811

Special Issue Editors

Dr. Gwang-Woong Go

E-Mail Website
Guest Editor
Department of Food and Nutrition, Hanyang University, Seoul 04763, Korea
Interests: nutrigenomics; obesity; bioactive compounds; lipid metabolism; metabolic syndromes
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Wooki Kim

E-Mail Website
Co-Guest Editor
Department of Food Science and Biotechnology, Kyung Hee University, Seoul, Republic of Korea
Interests: bioactive compounds; immunology; inflammation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The prevalence of chronic metabolic diseases is steadily growing worldwide, causing an increased burden for patients due to the deterioration of individual quality of life and the amassing of enormous socioeconomic costs. When addressing these issues, research on verifying the physiological activity of nutraceuticals containing bioactive compounds shows the possibility of preventive and therapeutic treatment. Moreover, the research on bioactive compounds expands into cutting-edge science by introducing state-of-the-art technologies. This Special Issue invites papers that research the recent development of nutraceuticals related to chronic metabolic diseases, obesity, type 2 diabetes mellitus, non-alcoholic fatty liver disease, inflammation, and dyslipidemia. This Special Issue aspires to provide the most trustworthy knowledge on the latest nutraceuticals to food scientists, nutritionists, and specialists to discover medicines. It is hoped that leading scientists in these fields will be able to contribute to yielding original results within this field.

Dr. Gwang-Woong Go 
Prof. Dr. Wooki Kim
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Foods is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nutraceutical
  • chronic metabolic diseases
  • nutrigenomics
  • non-alcoholic fatty liver disease
  • obesity
  • type 2 diabetes mellitus
  • inflammation
  • dyslipidemia

Published Papers (2 papers)

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Research

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16 pages, 7370 KiB  
Article
Anti-Obesity Effects of the Larval Powder of Steamed and Lyophilized Mature Silkworms in a Newly Designed Adult Mouse Model
by Min Woo Kim, Yu-Jin Ham, Hyun-Bok Kim, Ji young Lee, Jung-Dae Lim and Hyun-Tai Lee
Foods 2023, 12(19), 3613; https://doi.org/10.3390/foods12193613 - 28 Sep 2023
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Abstract
Recently, “mature” silkworms (MS) of Bombix mori have been considered a potential nutraceutical, with a number of health benefits reported for steamed and lyophilized MS powder (SMSP). However, no obesity-related effects have been reported for SMSP. In the present study, anti-obesity effects of [...] Read more.
Recently, “mature” silkworms (MS) of Bombix mori have been considered a potential nutraceutical, with a number of health benefits reported for steamed and lyophilized MS powder (SMSP). However, no obesity-related effects have been reported for SMSP. In the present study, anti-obesity effects of SMSP were investigated in adult mice in vivo, aged 12 weeks at the onset of SMSP treatment, fed a normal diet (ND) and a high-fat diet (HFD), respectively, for 12 weeks. SMSP significantly suppressed body weight gain, intra-abdominal adipose tissue, and food efficiency in both ND-fed and HFD-fed adult mice. In addition, SMSP significantly decreased food intake and liver weight in HFD-fed mice, indicating that SMSP suppressed appetite and simultaneously reduced the conversion of feed into body weight in HFD-fed mice. SMSP also significantly lowered the serum levels of glucose, triglyceride, total cholesterol, low-density lipoprotein cholesterol, asparagine transaminase, alanine transaminase, and alkaline phosphatase. However, SMSP had no significant effect on the weights of the kidney, spleen, or thymus or the serum levels of blood urea nitrogen and creatinine. Taken together, the above results suggest that SMSP has potent anti-obesity effects and is safe for long-term use as a potential therapeutic and/or nutraceutical in both obese patients and non-obese individuals. Full article
(This article belongs to the Special Issue New Insights into Nutraceuticals in the Prevention of Metabolic Syndrome)
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Review

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17 pages, 3376 KiB  
Review
Effect of the Combination of Hibiscus sabdariffa in Combination with Other Plant Extracts in the Prevention of Metabolic Syndrome: A Systematic Review and Meta-Analysis
by Ana María García-Muñoz, Ana I. García-Guillén, Desirée Victoria-Montesinos, María Salud Abellán-Ruiz, Begoña Alburquerque-González and Fernando Cánovas
Foods 2023, 12(11), 2269; https://doi.org/10.3390/foods12112269 - 05 Jun 2023
Cited by 2 | Viewed by 2468
Abstract
Metabolic syndrome is a complex and multifactorial disorder associated with increased risk of cardiovascular disease and type 2 diabetes, exacerbated by a sedentary lifestyle and situations such as the COVID-19 pandemic. Recent studies have shown that consumption of fruits and vegetables high in [...] Read more.
Metabolic syndrome is a complex and multifactorial disorder associated with increased risk of cardiovascular disease and type 2 diabetes, exacerbated by a sedentary lifestyle and situations such as the COVID-19 pandemic. Recent studies have shown that consumption of fruits and vegetables high in polyphenols has a protective effect, reducing cardiovascular risk. Hibiscus sabdariffa (HS) in combination with other plant extracts has recently attracted scientists’ attention due to its potential use in the treatment of metabolic syndrome. This systematic review and meta-analysis examines the effects of HS in combination with other plant extracts on the prevention of metabolic syndrome, exploring their synergistic effects and potential as therapeutic agents. For this purpose, a systematic search of randomized clinical trials (RCTs) was conducted in four different databases and the data obtained were then used for a meta-analysis. Initially, the titles and abstracts of 1368 studies were read. From these, 16 studies were examined closely for their eligibility, and finally, seven RCTs with 332 participants were included in both the meta-analysis and the qualitative analysis. Our results show that HS in combination with other plant extracts improved anthropometric parameters, blood pressure, and lipid profile (low density lipoprotein cholesterol and total cholesterol) compared to a placebo control group. It is important to note that although this meta-analysis suggests that HS in combination with other plant extracts may have a beneficial effect on cardiovascular parameters, further research is needed to determine the optimal dose and intake duration. Full article
(This article belongs to the Special Issue New Insights into Nutraceuticals in the Prevention of Metabolic Syndrome)
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