Green Antimicrobials in Biomedical Engineering: Recent Advances Proposal

A special issue of Antibiotics (ISSN 2079-6382).

Deadline for manuscript submissions: 30 June 2024 | Viewed by 2388

Special Issue Editor


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Guest Editor
Centre for Textile Science and Technology, University of Minho, Campus de Azurém, 4800-058 Guimarães, Portugal
Interests: antimicrobial agents concomitant; synergistic and additive effects surface functionalization; antimicrobial properties; biomedical therapies; bioactive molecules; green synthesis; environmentally friendly; circular economy; waste materials’ second life
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Special Issue Information

Dear Colleagues,

In recent years, the increasing awareness of climate change and high pollution levels has expanded our sense of ecological responsibility. The pharmaceutical industry is one of the most polluting industries. Additionally, new environmentally friendly approaches to deal with the growing concern associated with antimicrobial-resistant bacteria are also in great demand. The excessive consumption and misuse of pharmaceutical products, namely antibiotics, have accelerated the increase in such pathogens responsible for compromising global health, not only that of humans but of all living systems. Considering our natural resources are in great danger, finding green and less environmentally impactful alternatives for combating these resistant microbials is imperative. From green chemistries and natural extracts to waste products, the sources for these alternative antimicrobial agents can be immense and their impact of great importance for future generations. This Special Issue seeks to further our understanding of the antimicrobial action of specialized molecules (organic and inorganic) derived from green and ecofriendly processes as alternatives to conventional antibiotics or other antimicrobial agents. Submissions on the response of microorganisms to these agents, their contribution to infection control, and prevention of serious conditions/illnesses from occurring or evolving are especially encouraged. Publications on the chemical modification, transformation, or engineering of such green systems, with improved antimicrobial effects for biomedical purposes, are highly welcome.

Dr. Helena Felgueiras
Guest Editor

Manuscript Submission Information

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Keywords

  • antimicrobial agents concomitant
  • synergistic and additive effects surface functionalization
  • antimicrobial properties
  • biomedical therapies
  • bioactive molecules
  • green synthesis
  • environmentally friendly
  • circular economy
  • waste materials’ second life

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Published Papers (2 papers)

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Research

16 pages, 2328 KiB  
Article
Antifungal and Coagulation Properties of a Copper (I) Oxide Nanopowder Produced by Out-of-Phase Pulsed Sonoelectrochemistry
by Valérie Mancier, Sirine Fattoum, Hélène Haguet, Julie Laloy, Christina Maillet, Sophie C. Gangloff and Jean-Paul Chopart
Antibiotics 2024, 13(3), 286; https://doi.org/10.3390/antibiotics13030286 - 21 Mar 2024
Viewed by 787
Abstract
Copper (I) oxide (cuprite) is a material widely used nowadays, and its versatility is further amplified when it is brought to the nanometric size. Among the possible applications of this nanomaterial, one of the most interesting is that in the medical field. This [...] Read more.
Copper (I) oxide (cuprite) is a material widely used nowadays, and its versatility is further amplified when it is brought to the nanometric size. Among the possible applications of this nanomaterial, one of the most interesting is that in the medical field. This paper presents a cuprite nanopowder study with the aim of employing it in medical applications. With regards to the environmental context, the synthesis used is related to green chemistry since the technique (out-of-phase pulsed electrochemistry) uses few chemical products via electricity consumption and soft conditions of temperature and pressure. After different physico-chemical characterizations, the nanopowder was tested on the Candida albicans to determine its fungicide activity and on human blood to estimate its hemocompatibility. The results show that 2 mg of this nanopowder diluted in 30 µL Sabouraud broth was able to react with Candida albicans. The hemocompatibility tests indicate that for 25 to 100 µg/mL of nanopowder in an aqueous medium, the powder was not toxic for human blood (no hemolysis nor platelet aggregation) but promoted blood coagulation. It appears, therefore, as a potential candidate for the functionalization of matrices for medical applications (wound dressing or operating field, for example). Full article
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14 pages, 5955 KiB  
Article
The In Vitro Antibacterial Activity of Argirium SUNc against Most Common Pathogenic and Spoilage Food Bacteria
by Andrea Mancusi, Marica Egidio, Raffaele Marrone, Luca Scotti, Domenico Paludi, Irene Dini and Yolande Thérèse Rose Proroga
Antibiotics 2024, 13(1), 109; https://doi.org/10.3390/antibiotics13010109 - 22 Jan 2024
Viewed by 1258
Abstract
Foodborne diseases are one of the main issues for human health, and antibacterial packaging plays a major role in food security assurance. Silver ultra nanoparticles (Argirium SUNc) are antimicrobial agents that have a wide spectrum of action, including against pathogenic bacteria and spoilage [...] Read more.
Foodborne diseases are one of the main issues for human health, and antibacterial packaging plays a major role in food security assurance. Silver ultra nanoparticles (Argirium SUNc) are antimicrobial agents that have a wide spectrum of action, including against pathogenic bacteria and spoilage fungi. The aim of the present study was to evaluate the antibacterial activity of Argirium SUNc on the bacteria most commonly found in food: Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Listeria monocytogenes, and Salmonella typhimurium. In this regard, an in vitro study was carried out by assessing the Argirium SUNc effectiveness on different concentrations of each tested microbial strain and at different time intervals. The data showed that the antimicrobial activity of Argirium SUNc was directly related to the microbial concentration and varied depending on the microbial species. Moreover, a greater effectiveness against Gram-negative bacteria than Gram-positive bacteria was observed. These preliminary results provided important information on the silver nanoparticles spectrum of action, and this is an aspect that appears particularly promising for obtaining a viable alternative to traditional antimicrobials to be used against the pathogens and spoilage agents most commonly found in the food chain, harmful both to health and quality aspects. Full article
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