Dietary Intake of Natural Molecules, Diseases and Health

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Phytochemicals and Human Health".

Deadline for manuscript submissions: 15 July 2024 | Viewed by 3320

Special Issue Editor


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Guest Editor
Department of Anatomy, School of Basic Medicine, Peking University, Beijing 100191, China
Interests: nutrition and chronic diseases; obesity; intervention; nutrients; natural molecules; cancer
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Natural molecules are possessed with mechanisms of action that can intervene in multiple disease targets and pathways, which have stimulated considerable interest among researchers in natural drug therapies. Natural molecules are characterized by several advantages, such as fewer adverse reactions, significant therapeutic effects, and the ability to function in synergy with multiple components. Compared to traditional synthesized small-molecule drugs, natural molecules also have the advantages of abundant resources, low cost, and easy availability, making them an important source of new drug development. More than half of the new chemical entity drugs developed internationally are directly or indirectly derived from natural molecules. Natural molecules have enormous medical value and market potential.

This Special Issue aims to describe and stress the importance of natural molecules in human health and disease development; understand the mechanism(s) whereby natural molecules can affect disease development; and examine potential novel therapies. This Special Issue, titled “Dietary Intake of Natural Molecules, Diseases and Health”, is open for the submission of articles and reviews describing the available literature and research evidence, with a critical examination of the data and identification of current research outcomes and study limitations and potential advances in knowledge in the research area. Exploring the effects of natural molecules, including nutrients, supplements, or extracts from plants on disease development, is within the scope of this study. This includes all types of disease, exploring direct or future effects from animal or human studies. The content may be useful for clinical practitioners and inspire further innovative research.

Dr. Junbo Wang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Keywords

  • natural molecules
  • diseases developments
  • human health
  • mechanism
  • novel therapies

Published Papers (1 paper)

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Review

19 pages, 1666 KiB  
Review
Targeting Metabolic Diseases: The Role of Nutraceuticals in Modulating Oxidative Stress and Inflammation
by Aida Dama, Kleva Shpati, Patricia Daliu, Seyma Dumur, Era Gorica and Antonello Santini
Nutrients 2024, 16(4), 507; https://doi.org/10.3390/nu16040507 - 10 Feb 2024
Cited by 3 | Viewed by 3144
Abstract
The escalating prevalence of metabolic and cardiometabolic disorders, often characterized by oxidative stress and chronic inflammation, poses significant health challenges globally. As the traditional therapeutic approaches may sometimes fall short in managing these health conditions, attention is growing toward nutraceuticals worldwide; with compounds [...] Read more.
The escalating prevalence of metabolic and cardiometabolic disorders, often characterized by oxidative stress and chronic inflammation, poses significant health challenges globally. As the traditional therapeutic approaches may sometimes fall short in managing these health conditions, attention is growing toward nutraceuticals worldwide; with compounds being obtained from natural sources with potential therapeutic beneficial effects being shown to potentially support and, in some cases, replace pharmacological treatments, especially for individuals who do not qualify for conventional pharmacological treatments. This review delves into the burgeoning field of nutraceutical-based pharmacological modulation as a promising strategy for attenuating oxidative stress and inflammation in metabolic and cardiometabolic disorders. Drawing from an extensive body of research, the review showcases various nutraceutical agents, such as polyphenols, omega-3 fatty acids, and antioxidants, which exhibit antioxidative and anti-inflammatory properties. All these can be classified as novel nutraceutical-based drugs that are capable of regulating pathways to mitigate oxidative-stress- and inflammation-associated metabolic diseases. By exploring the mechanisms through which nutraceuticals interact with oxidative stress pathways and immune responses, this review highlights their potential to restore redox balance and temper chronic inflammation. Additionally, the challenges and prospects of nutraceutical-based interventions are discussed, encompassing bioavailability enhancement, personalized treatment approaches, and clinical translation. Through a comprehensive analysis of the latest scientific reports, this article underscores the potential of nutraceutical-based pharmacological treatment modulation as a novel avenue to fight oxidative stress and inflammation in the complex landscape of metabolic disorders, particularly accentuating their impact on cardiovascular health. Full article
(This article belongs to the Special Issue Dietary Intake of Natural Molecules, Diseases and Health)
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