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Nutrients
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OPERA 2021 (Obesity Programs of Nutrition, Education, Research and Assessment...
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OPERA 2021 (Obesity Programs of Nutrition, Education, Research and Assessment of the Best Treatment): Obesity and Low Grade Inflammation

A special issue of Nutrients (ISSN 2072-6643).

Deadline for manuscript submissions: closed (1 April 2022) | Viewed by 20389

Special Issue Editors

Prof. Dr. Annamaria Colao

E-Mail Website
Guest Editor
Dipartimento di Medicina Clinica e Chirurgia, Unit of Endocrinology, Federico II University Medical School of Naples, 80131 Naples, Italy
Interests: endocrinology of women–contraception–menopause; geriatric endocrinology; hypothalamus–pituitary–neuroendocrinology; nutritional epidemiology; clinical trials; obesity and susceptibility to infections; obesity-related cardiovascular diseases; diet and type 2 diabetes
Special Issues, Collections and Topics in MDPI journals
Dr. Chiara Graziadio

E-Mail Website
Guest Editor
Division of Endocrinology, AOU Federico II, Napoli, Italy
Interests: obesity; nutritional epidemiology; clinical trials; obesity-related cardiovascular diseases; diet and type 2 diabetes; thyroid ultrasonography; thyroid diseases
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The scientific meeting OPERA 2021 will take place in Naples, Italy, on 17–18 September 2021. The workshop will treat the pathophysiological bases of obesity, up to the latest news in the field of pharmacological and surgical treatments, with the following training objectives: 1) update on chronic inflammation; 2) update on comorbidities caused by obesity-related chronic inflammation, such as T2DM, dyslipidemia, cancer, and any pharmacological approaches; 3) identification of lifestyle interventions that can prevent and treat obesity from a nutritional and physical activity approach; and 4) update on the latest pharmacological innovations and surgical strategies for the treatment of obesity with beneficial effects also on the degree of chronic inflammation. We plan on publishing at least 10 manuscripts on these topics. 

Prof. Dr. Annamaria Colao
Dr. Chiara Graziadio
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Obesity
  • Inflammation
  • T2DM
  • Dyslipidemia
  • Cancer
  • Body weight
  • Vitamin  D
  • Diet
  • Physical activity
  • Bariatric surgery

Published Papers (3 papers)

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Review

27 pages, 2067 KiB  
Review
Epicardial Adipose Tissue: A Novel Potential Imaging Marker of Comorbidities Caused by Chronic Inflammation
by Maria Grazia Tarsitano, Carla Pandozzi, Giuseppe Muscogiuri, Sandro Sironi, Arturo Pujia, Andrea Lenzi and Elisa Giannetta
Nutrients 2022, 14(14), 2926; https://doi.org/10.3390/nu14142926 - 17 Jul 2022
Cited by 13 | Viewed by 3323
Abstract
The observation of correlations between obesity and chronic metabolic and cardiovascular diseases has led to the emergence of strong interests in “adipocyte biology”, in particular in relation to a specific visceral adipose tissue that is the epicardial adipose tissue (EAT) and its pro-inflammatory [...] Read more.
The observation of correlations between obesity and chronic metabolic and cardiovascular diseases has led to the emergence of strong interests in “adipocyte biology”, in particular in relation to a specific visceral adipose tissue that is the epicardial adipose tissue (EAT) and its pro-inflammatory role. In recent years, different imaging techniques frequently used in daily clinical practice have tried to obtain an EAT quantification. We provide a useful update on comorbidities related to chronic inflammation typical of cardiac adiposity, analyzing how the EAT assessment could impact and provide data on the patient prognosis. We assessed for eligibility 50 papers, with a total of 10,458 patients focusing the review on the evaluation of EAT in two main contexts: cardiovascular and metabolic diseases. Given its peculiar properties and rapid responsiveness, EAT could act as a marker to investigate the basal risk factor and follow-up conditions. In the future, EAT could represent a therapeutic target for new medications. The assessment of EAT should become part of clinical practice to help clinicians to identify patients at greater risk of developing cardiovascular and/or metabolic diseases and to provide information on their clinical and therapeutic outcomes. Full article
(This article belongs to the Special Issue OPERA 2021 (Obesity Programs of Nutrition, Education, Research and Assessment of the Best Treatment): Obesity and Low Grade Inflammation)
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12 pages, 798 KiB  
Review
From Gut Microbiota through Low-Grade Inflammation to Obesity: Key Players and Potential Targets
by Claudia Vetrani, Andrea Di Nisio, Stavroula A. Paschou, Luigi Barrea, Giovanna Muscogiuri, Chiara Graziadio, Silvia Savastano, Annamaria Colao and on behalf of the Obesity Programs of Nutrition, Education, Research and Assessment (OPERA) Group
Nutrients 2022, 14(10), 2103; https://doi.org/10.3390/nu14102103 - 18 May 2022
Cited by 28 | Viewed by 4509
Abstract
During the last decades, the gut microbiota has gained much interest in relation to human health. Mounting evidence has shown a strict association between gut microbiota and obesity and its related diseases. Inflammation has been appointed as the driving force behind this association. [...] Read more.
During the last decades, the gut microbiota has gained much interest in relation to human health. Mounting evidence has shown a strict association between gut microbiota and obesity and its related diseases. Inflammation has been appointed as the driving force behind this association. Therefore, a better understanding of the mechanisms by which gut microbiota might influence inflammation in the host could pave for the identification of effective strategies to reduce inflammation-related diseases, such as obesity and obesity-related diseases. For this purpose, we carried out an extensive literature search for studies published in the English language during the last 10 years. Most relevant studies were used to provide a comprehensive view of all aspects related to the association of gut microbiota and low-grade inflammation with obesity. Accordingly, this narrative review reports the evidence on the key players supporting the role of gut microbiota in the modulation of inflammation in relation to obesity and its complications. Moreover, therapeutic approaches to reduce microbiota-related inflammation are discussed to provide potential targets for future research. Full article
(This article belongs to the Special Issue OPERA 2021 (Obesity Programs of Nutrition, Education, Research and Assessment of the Best Treatment): Obesity and Low Grade Inflammation)
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23 pages, 2341 KiB  
Review
Anti-Inflammatory Nutrients and Obesity-Associated Metabolic-Inflammation: State of the Art and Future Direction
by Giuseppe Grosso, Daniela Laudisio, Evelyn Frias-Toral, Luigi Barrea, Giovanna Muscogiuri, Silvia Savastano and Annamaria Colao
Nutrients 2022, 14(6), 1137; https://doi.org/10.3390/nu14061137 - 08 Mar 2022
Cited by 53 | Viewed by 11870
Abstract
Growing evidence supports the hypothesis that dietary factors may play a role in systemic low-grade chronic inflammation. Summary evidence from randomized controlled trials has shown substantial effects on biomarkers of inflammation following the adoption of plant-based diets (including, but not limited to, the [...] Read more.
Growing evidence supports the hypothesis that dietary factors may play a role in systemic low-grade chronic inflammation. Summary evidence from randomized controlled trials has shown substantial effects on biomarkers of inflammation following the adoption of plant-based diets (including, but not limited to, the Mediterranean diet), while consistent findings have been reported for higher intakes of whole grains, fruits, and vegetables and positive trends observed for the consumption of legumes, pulses, nuts, and olive oil. Among animal food groups, dairy products have been shown to have the best benefits on biomarkers of inflammation, while red meat and egg have been shown to have neutral effects. The present review provides an overview of the mechanisms underlying the relation between dietary factors and immune system, with a focus on specific macronutrient and non-nutrient phytochemicals (polyphenols) and low-grade inflammation. Substantial differences within each macronutrient group may explain the conflicting results obtained regarding foods high in saturated fats and carbohydrates, underlying the role of specific subtypes of molecules (i.e., short-chain fatty acids or fiber vs. long chain fatty acids or free added sugars) when exploring the relation between diet and inflammation, as well as the importance of the food matrix and the commixture of foods in the context of whole dietary patterns. Dietary polyphenols and oligopeptides have been hypothesized to exert several functions, including the regulation of the inflammatory response and effects on the immune system. Overall, evidence suggests that dietary factors may affect the immune system regardless of obesity-related inflammation. Full article
(This article belongs to the Special Issue OPERA 2021 (Obesity Programs of Nutrition, Education, Research and Assessment of the Best Treatment): Obesity and Low Grade Inflammation)
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