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Role of Anti-inflammatory Adipokines in Obesity-Related Diseases

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Obesity".

Deadline for manuscript submissions: closed (20 May 2023) | Viewed by 4457

Special Issue Editor


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Guest Editor
Department of Biochemistry and Experimental Medicine, The Children’s Memorial Health Institute, 04-761 Warsaw, Poland
Interests: metabolic syndrome; metabolomics; obesity; chronic liver disease; lipoproteins; vitamins; antioxidants; non-alcoholic fatty liver disease; fatty acids; nutrition; inflammation
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Special Issue Information

Dear Colleagues,

We are pleased to invite you to submit to our new Special Issue on the “Role of Anti-Inflammatory Adipokines in Obesity-Related Diseases” in the Section “Nutrition and Obesity” of the journal Nutrients, which highlights the most recent findings concerning the anti-inflammatory role and function of anti-inflammatory adipokines  as a result of  lipid accumulation, the development of oxidative stress and cell T and B activation, and the role of obesity in systemic inflammation. Nutrition, diet, physical activity, and exercise provide general and prescriptive avenues to target a range of deleterious effects of obesity-related diseases and their treatment and progression. This Special Issue welcomes the following submission types for obesity and obesity-related diseases:

(1) Narrative, scoping, or systematic reviews;

(2) Original research articles including clinical and randomized controlled trials;

(3) Health services research, including implementation science interventions canvassing topics within the nutrition, dietetics, physical activity, and exercise disciplines.

We sincerely hope our invitation will receive your favorable consideration.

Dr. Aldona Wierzbicka-Rucinska
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • anti-inflammatory adipokines
  • dietary intervention
  • gut microbiome
  • defensins
  • NAFLD
  • oxidative stress
  • iron
  • antioxidants

Published Papers (2 papers)

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Research

15 pages, 1160 KiB  
Article
Serum Antioxidant Vitamins Mediate the Association between Periodontitis and Metabolically Unhealthy Overweight/Obesity
by An Li, Zhi Tang, Peijun Zhu, Florien van den Bosch, Yuntao Chen, Shulan Xu and Geerten-Has E. Tjakkes
Nutrients 2022, 14(22), 4939; https://doi.org/10.3390/nu14224939 - 21 Nov 2022
Cited by 3 | Viewed by 2035
Abstract
Background: Periodontal disease is associated with metabolic syndrome and obesity. This cross-sectional study aimed to investigate whether serum antioxidant vitamins could mediate the association between periodontitis and a metabolically unhealthy phenotype in the overweight and obese population; Methods: We included 6158 Americans (body [...] Read more.
Background: Periodontal disease is associated with metabolic syndrome and obesity. This cross-sectional study aimed to investigate whether serum antioxidant vitamins could mediate the association between periodontitis and a metabolically unhealthy phenotype in the overweight and obese population; Methods: We included 6158 Americans (body mass index (BMI) ≥ 25 kg/m2) from the Third National Health and Nutrition Examination Survey (NHANES III). Periodontitis was defined using a half-reduced CDC/AAP (Centers for Disease Control and Prevention/American Academy of Periodontology) definition. Having two or more metabolic abnormalities was defined as a metabolically unhealthy overweight and obese (MUO) phenotype. Mediation analysis of four oxidative stress biomarkers (serum antioxidant vitamins A, C, D, and E) was conducted; Results: Of participants with overweight and obesity, 2052 (33.3%) Americans were categorized as having periodontitis. Periodontitis increased dyslipidemia risk and systemic inflammation in the overweight and obese population. In the multivariable logistic regression model, periodontitis was positively associated with MUO (adjusted odds ratio = 1.238; 95% confidence interval: 1.091 to 1.406). These findings were validated in an independent cohort. Serum vitamins C and D were estimated to mediate 19.3% and 8.4% of the periodontitis–MUO association. Conclusions: Periodontitis might decrease serum vitamins C and D and induce a metabolically unhealthy state among adults with overweight and obesity. Full article
(This article belongs to the Special Issue Role of Anti-inflammatory Adipokines in Obesity-Related Diseases)
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13 pages, 559 KiB  
Article
Understanding the Complexities of Eliminating Trans Fatty Acids: The Case of the Trans Fatty Acid Ban in Thailand
by Weerapak Samsiripong, Sirinya Phulkerd, Umaporn Pattaravanich and Manasigan Kanchanachitra
Nutrients 2022, 14(13), 2748; https://doi.org/10.3390/nu14132748 - 01 Jul 2022
Cited by 1 | Viewed by 1997
Abstract
Trans fatty acids (TFAs) have no known health benefits and are linked to an increased risk of noncommunicable diseases (NCDs). To eliminate TFAs from the food supply, the government of Thailand imposed a ban on partially hydrogenated oils (PHOs) in 2018. This study [...] Read more.
Trans fatty acids (TFAs) have no known health benefits and are linked to an increased risk of noncommunicable diseases (NCDs). To eliminate TFAs from the food supply, the government of Thailand imposed a ban on partially hydrogenated oils (PHOs) in 2018. This study was aimed at analyzing the government policies and actions to eliminate TFAs in Thailand, focusing on policy content, context, process, and actors. This single-case qualitative study used a documentary review and interviews with 20 key policy actors. The data analysis was guided by thematic analysis based on the policy triangle framework. The results reveal that policy actors—government organizations, academics, civil society organizations, and the food industry—have different roles, interests, and influences with regard to eliminating TFAs in Thailand. Both formal and informal communication among policy actors aided in the policymaking process and the actions that followed. Changing perceptions of TFAs, the low intake of PHOs in Thailand, hype around trans fats, and trade dynamics shaped the government’s decision to impose the ban. As a result, the ban was selected to avoid the technical components of TFA elimination. This study suggests that eliminating TFAs in Thailand could be further enhanced by strengthening government actions in terms of enforcement and creating consumer awareness. Full article
(This article belongs to the Special Issue Role of Anti-inflammatory Adipokines in Obesity-Related Diseases)
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