Dietary Nitrate in Health and Diseases: Pathways from Nitrate and NOS to Nitric Oxide and Beyond
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Metabolism".
Deadline for manuscript submissions: 25 June 2024 | Viewed by 639
Special Issue Editor
Interests: nitrate reductive pathway; mammalian nitrate reservoirs; nitric oxide; mammalian nitrate reductase; ageing; diabetes; degenerative eye diseases; cardiovascular disease; exercise; neuromuscular diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We are pleased to announce our plans to publish the following Special Issue of Nutrients: “Dietary Nitrate in Health and Diseases: Pathways from Nitrate and NOS to Nitric Oxide and Beyond”.
The goal of this Special Issue is to bring together authors from different aspects and corners of the nitric oxide (NO) field to create a fresh view of multiple roles of NO and its metabolites in physiology and to highlight functional transformations of NO.
NO metabolism is dysfunctional in many metabolic, cardiovascular, and neuromuscular diseases, and increasing NO can improve the quality of life of some patients. Even healthy people can benefit from increased NO levels, especially aging people and athletes. The NO precursor, nitrate, is found in many vegetables, which allows everybody “in need of increased NO” to profit from simple dietary intervention. So far, research using dietary nitrate has led to conclusions that it is safe; studies either showed a benefit or no change, with no harm detected. However, more clinical research is needed to understand the basic normal physiology of dietary nitrate transformation into nitric oxide and beyond, as well as sites of its dysfunction in diseases.
We aim to publish the most recent developments within the NO field, hopefully even “beyond” NO itself, such as the role of nitrosothiols (famous “SNO”) and nitro-fatty acids. We also hope that new questions and hypotheses about NO transformations arise in this Special Issue of Nutrients.
Dr. Barbora Piknova
Guest Editor
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- nitrate/nitrite/nitric oxide
- nitric oxide synthase (NOS)
- S-nitrosothiols (SNO)
- nitro-fatty acids
- nitrate/nitrite transporter (sialin, CLC)
- nitrate/nitrite reductase
- oral and gut microbiome
- diabetes
- endothelial dysfunction
- metabolic syndrome
- cardiovascular diseases
- ageing
- athletic performance
- neuromuscular diseases
