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Nutrients
Special Issues
Dietary Interventions for Patients with Type 2 Diabetes
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Dietary Interventions for Patients with Type 2 Diabetes

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Diabetes".

Deadline for manuscript submissions: 25 August 2024 | Viewed by 9509

Special Issue Editor

Prof. Dr. Iskandar Idris

E-Mail Website
Guest Editor
Division of Medical Sciences and Graduate Entry Medicine, School of Medicine, University of Nottingham, Nottingham DE223DT, UK
Interests: obesity; type 2 diabetes; metabolic medicine

Special Issue Information

Dear Colleagues,

Evidence continues to emerge regarding the beneficial effects of various dietary and nutritional interventions when aiming to improve glycemic control and weight management in people with type 2 diabetes. Recommendations regarding diet and nutrition typically focus on weight loss, healthy foods (e.g., low-fat, high-fiber, and whole-grain foods), and caloric restriction, the latter focusing on macronutrient and micronutrient composition in order to optimize muscle health. More recently, ‘remission’-based treatment has been proposed as a treatment objective. Such strategies may include a very-low-calorie diet, carbohydrate restrictions, and whole-food plant-based diet options, among many others. Meanwhile, innovative research studies have investigated the underlying mechanisms of nutrition in regulating glucose metabolism, as well as the interactions among diet, genetics, epigenetics, and the gut microbiota.

The Special Issue will discuss the relationship between dietary interventions and type 2 diabetes. It aims to enhance our understanding of the various mechanistic pathways that contribute to type 2 diabetes, present current research concerning the associations between different micro-nutrients or macro-nutrients and glucose homeostasis and metabolism, and to elucidate dietary intervention strategies that may improve glucose control, induce weight loss and/or diabetes remission. We also encourage the submission of manuscripts that explore the possible relationship between nutrients and genetic factors, and explore precision nutrition strategies based on individuals’ genotype and microbiota for the prevention and amelioration of type 2 diabetes. In this Special Issue of Nutrients, we welcome both original research or reviews on the current state of research.

Prof. Dr. Iskandar Idris
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nutrition
  • dietary intervention
  • type 2 diabetes
  • metabolism
  • obesity
  • weight
  • diabetes remission
  • macro-nutrient
  • macronutrient
  • carbohydrate
  • amino acids
  • protein
  • mechanism
  • genetics
  • gut microbiota

Published Papers (3 papers)

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Research

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17 pages, 903 KiB  
Article
Efficacy of Time-Restricted Eating and Behavioral Economic Intervention in Reducing Fasting Plasma Glucose, HbA1c, and Cardiometabolic Risk Factors in Patients with Impaired Fasting Glucose: A Randomized Controlled Trial
by Unyaporn Suthutvoravut, Thunyarat Anothaisintawee, Suparee Boonmanunt, Sarunporn Pramyothin, Sukanya Siriyothin, John Attia, Gareth J. McKay, Sirimon Reutrakul and Ammarin Thakkinstian
Nutrients 2023, 15(19), 4233; https://doi.org/10.3390/nu15194233 - 30 Sep 2023
Viewed by 2300
Abstract
This randomized controlled trial is aimed at assessing the efficacy of combining time-restricted eating (TRE) with behavioral economic (BE) interventions and comparing it to TRE alone and to the usual care for reducing fasting plasma glucose (FPG), hemoglobin A1c (HbA1c), and other cardiometabolic [...] Read more.
This randomized controlled trial is aimed at assessing the efficacy of combining time-restricted eating (TRE) with behavioral economic (BE) interventions and comparing it to TRE alone and to the usual care for reducing fasting plasma glucose (FPG), hemoglobin A1c (HbA1c), and other cardiometabolic risk factors among patients with impaired fasting glucose (IFG). Seventy-two IFG patients aged 18–65 years were randomly allocated for TRE with BE interventions (26 patients), TRE alone (24 patients), or usual care (22 patients). Mean FPG, HbA1c, and other cardiometabolic risk factors among the three groups were compared using a mixed-effect linear regression analysis. Mean body weight, FPG, HbA1c, fasting insulin, and lipid profiles did not significantly differ among the three groups. When considering only patients who were able to comply with the TRE protocol, the TRE group showed significantly lower mean FPG, HbA1c, and fasting insulin levels compared to the usual care group. Our results did not show significant differences in body weight, blood sugar, fasting insulin, or lipid profiles between TRE plus BE interventions, TRE alone, and usual care groups. However, TRE might be an effective intervention in lowering blood sugar levels for IFG patients who were able to adhere to the TRE protocol. Full article
(This article belongs to the Special Issue Dietary Interventions for Patients with Type 2 Diabetes)
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Review

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40 pages, 2535 KiB  
Review
Nutrition at the Intersection between Gut Microbiota Eubiosis and Effective Management of Type 2 Diabetes
by Sevag Hamamah, Oana C. Iatcu and Mihai Covasa
Nutrients 2024, 16(2), 269; https://doi.org/10.3390/nu16020269 - 16 Jan 2024
Cited by 1 | Viewed by 2618
Abstract
Nutrition is one of the most influential environmental factors in both taxonomical shifts in gut microbiota as well as in the development of type 2 diabetes mellitus (T2DM). Emerging evidence has shown that the effects of nutrition on both these parameters is not [...] Read more.
Nutrition is one of the most influential environmental factors in both taxonomical shifts in gut microbiota as well as in the development of type 2 diabetes mellitus (T2DM). Emerging evidence has shown that the effects of nutrition on both these parameters is not mutually exclusive and that changes in gut microbiota and related metabolites such as short-chain fatty acids (SCFAs) and branched-chain amino acids (BCAAs) may influence systemic inflammation and signaling pathways that contribute to pathophysiological processes associated with T2DM. With this background, our review highlights the effects of macronutrients, carbohydrates, proteins, and lipids, as well as micronutrients, vitamins, and minerals, on T2DM, specifically through their alterations in gut microbiota and the metabolites they produce. Additionally, we describe the influences of common food groups, which incorporate varying combinations of these macronutrients and micronutrients, on both microbiota and metabolic parameters in the context of diabetes mellitus. Overall, nutrition is one of the first line modifiable therapies in the management of T2DM and a better understanding of the mechanisms by which gut microbiota influence its pathophysiology provides opportunities for optimizing dietary interventions. Full article
(This article belongs to the Special Issue Dietary Interventions for Patients with Type 2 Diabetes)
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27 pages, 522 KiB  
Review
Nutritional Strategies for the Management of Type 2 Diabetes Mellitus: A Narrative Review
by Tatiana Palotta Minari, Lúcia Helena Bonalume Tácito, Louise Buonalumi Tácito Yugar, Sílvia Elaine Ferreira-Melo, Carolina Freitas Manzano, Antônio Carlos Pires, Heitor Moreno, José Fernando Vilela-Martin, Luciana Neves Cosenso-Martin and Juan Carlos Yugar-Toledo
Nutrients 2023, 15(24), 5096; https://doi.org/10.3390/nu15245096 - 13 Dec 2023
Cited by 3 | Viewed by 4223
Abstract
Background: Thinking about greater adherence to dietary planning, it is extremely important to be aware of all nutritional strategies and dietary prescriptions available in the literature, and of which of them is the most efficient for the management of T2DM. Methods: A search [...] Read more.
Background: Thinking about greater adherence to dietary planning, it is extremely important to be aware of all nutritional strategies and dietary prescriptions available in the literature, and of which of them is the most efficient for the management of T2DM. Methods: A search was carried out in 2023 for randomized clinical trials, systematic reviews, meta-analyses, and guidelines in the following databases: Pubmed, Scielo, Web of Science, CrossRef and Google Scholar. In total, 202 articles were collected and analyzed. The period of publications was 1983–2023. Results: There is still no consensus on what the best nutritional strategy or ideal dietary prescription is, and individuality is necessary. In any case, these references suggest that Mediterranean Diet may of greater interest for the management of T2DM, with the following recommended dietary prescription: 40–50% carbohydrates; 15–25% proteins; 25–35% fats (<7% saturated, 10% polyunsaturated, and 10% monounsaturated); at least 14 g of fiber for every 1000 kcal consumed; and <2300 mg sodium. Conclusions: Individuality is the gold standard for dietary prescriptions, however, the Mediterranean diet with low levels of carbohydrates and fats seems to be the most promising strategy for the management of T2DM. Full article
(This article belongs to the Special Issue Dietary Interventions for Patients with Type 2 Diabetes)
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