Dietary Intake and Nutritional Management of Chronic Kidney Disease

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".

Deadline for manuscript submissions: 5 July 2024 | Viewed by 2119

Special Issue Editors


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Guest Editor
Néphrologie Et Dialyse, Centre Hospitalier Le Mans, 194 Avenue Rubillard, 72000 Le Mans, France
Interests: chronic kidney disease; nutrition in CKD; diabetic nephropathy; aging; dialysis; pregnancy and CKD
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Guest Editor
Unit of Nephrology, Dialysis and Kidney Transplantation, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico di Milano, 20122 Milan, Italy
Interests: nutrition; chronic kidney disease; dialysis; kidney transplantation; malnutrition; diet

Special Issue Information

Dear Colleagues,

Nutritional therapy plays an important role in the prevention and progression of chronic kidney disease (CKD). In recent years, dietary management of patients with CKD has expanded the range of dietary interventions to include CKD stage 3, emphasising that optimising protein intake is associated with reduced mortality and morbidity. At the same time, the prevention and treatment of malnutrition (whether undernourished or overnourished) and protein energy wasting (PEW) is imperative in both conservative and replacement therapies.

Several dietary approaches have been proposed. However, assessing patients' needs and personalised approaches with individual risk-benefit assessments should be sought. The most successful nutritional management is the one that is tailored to the needs of the patient.

This Special Issue titled “Dietary Intake and Nutritional Management of Chronic Kidney Disease” is open for original articles and reviews focusing on nutrition and metabolism in patients with CKD in both conservative and replacement treatments.

Dr. Massimo Torreggiani
Dr. Lara Caldiroli
Guest Editor

Manuscript Submission Information

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Keywords

  • chronic kidney disease (CKD)
  • dialysis
  • kidney transplantation
  • obesity
  • low protein diet
  • malnutrition
  • nutritional status
  • oral supplementation

Published Papers (2 papers)

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Research

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11 pages, 260 KiB  
Article
Changes in Dietary Nutrient Intake and Estimated Glomerular Filtration Rate over a 5-Year Period in Renal Transplant Recipients
by I-Hsin Lin, Yi-Chun Chen, Tuyen Van Duong, Shih-Wei Nien, I-Hsin Tseng, Yi-Ming Wu, Hsu-Han Wang, Yang-Jen Chiang, Chia-Yu Chiang, Chia-Hui Chiu, Ming-Hsu Wang, Nien-Chieh Yang and Te-Chih Wong
Nutrients 2024, 16(1), 148; https://doi.org/10.3390/nu16010148 - 31 Dec 2023
Cited by 2 | Viewed by 1028
Abstract
The scarcity of dietary guidance for renal transplant recipients (RTRs) raises concerns regarding obesity and associated comorbidities, including impaired renal function. This two-stage cross-sectional study examined longitudinal changes in dietary nutrient intake in the same individuals over a 5-year interval. This study involved [...] Read more.
The scarcity of dietary guidance for renal transplant recipients (RTRs) raises concerns regarding obesity and associated comorbidities, including impaired renal function. This two-stage cross-sectional study examined longitudinal changes in dietary nutrient intake in the same individuals over a 5-year interval. This study involved two stages: T1 (September 2016 to June 2018) and T2 (July 2022 to August 2023). The average duration between the two data collection stages was 6.17 ± 0.42 (range 5.20–6.87) years. The study included 227 RTRs with an average age and time since transplant of 49.97 ± 12.39 and 9.22 ± 7.91 years, respectively. Of the 35 patients who participated in both phases, fewer than half met the recommended intakes for energy, dietary fiber, and most vitamins and minerals, as set in the Dietary Reference Intakes (DRIs) or by the Dietitian Association Australia (DAA). Over half exceeded the DRI recommended intake for total protein, and more than 80% of the protein consumed per kilogram of body weight exceeded the DAA’s recommendations. In the T2 stage, the RTRs had a significantly higher blood urea nitrogen level, lower albumin level, and estimated glomerular filtration rate. These findings indicate that deteriorating dietary intake in RTRs can adversely affect their nutritional status and transplanted kidney function over a 5-year period. Full article
(This article belongs to the Special Issue Dietary Intake and Nutritional Management of Chronic Kidney Disease)

Review

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16 pages, 1099 KiB  
Review
Diet and Physical Activity in Fabry Disease: A Narrative Review
by Giovanna Muscogiuri, Oriana De Marco, Tonia Di Lorenzo, Maria Amicone, Ivana Capuano, Eleonora Riccio, Guido Iaccarino, Antonio Bianco, Teodolinda Di Risi and Antonio Pisani
Nutrients 2024, 16(7), 1061; https://doi.org/10.3390/nu16071061 - 04 Apr 2024
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Abstract
Fabry disease (FD) is caused by mutations in the galactosidase alpha (GLA) gene which lead to the accumulation of globotriaosylceramide (Gb-3). Enzyme replacement therapy (ERT) and oral chaperone therapy are the current pharmacological treatments for this condition. However, in the literature, there is [...] Read more.
Fabry disease (FD) is caused by mutations in the galactosidase alpha (GLA) gene which lead to the accumulation of globotriaosylceramide (Gb-3). Enzyme replacement therapy (ERT) and oral chaperone therapy are the current pharmacological treatments for this condition. However, in the literature, there is a growing emphasis on exploring non-pharmacological therapeutic strategies to improve the quality of life of patients with FD. In particular, the nutritional approach to FD has been marginally addressed in the scientific literature, although specific dietary interventions may be useful for the management of nephropathy and gastrointestinal complications, which are often present in patients with FD. Especially in cases of confirmed diagnosis of irritable bowel syndrome (IBS), a low-FODMAP diet can represent an effective approach to improving intestinal manifestations. Furthermore, it is known that some food components, such as polyphenols, may be able to modulate some pathogenetic mechanisms underlying the disease, such as inflammation and oxidative stress. Therefore, the use of healthy dietary patterns should be encouraged in this patient group. Sports practice can be useful for patients with multi-organ involvement, particularly in cardiovascular, renal, and neurological aspects. Therefore, the aim of this review is to summarize current knowledge on the role of nutrition and physical activity in FD patients. Full article
(This article belongs to the Special Issue Dietary Intake and Nutritional Management of Chronic Kidney Disease)
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