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Nutrients
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Featured Reviews on Prebiotics and Probiotics
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Featured Reviews on Prebiotics and Probiotics

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Prebiotics and Probiotics".

Deadline for manuscript submissions: closed (8 November 2023) | Viewed by 10600

Special Issue Editor

Dr. Lorella Paparo

E-Mail Website
Guest Editor
Department of Transational Medical Science, University of Naples Federico II, Naples, Italy
Interests: gut microbiome; food allergy; nutrition; postbiotics; probiotics; epigenetics; ultra-processed foods; gastrointestinal disorders; butyrate

Special Issue Information

Dear Colleagues,

As is well known, prebiotics and probiotics play an important role in improving human health. In the last decade, extensive studies have reported the beneficial effect of prebiotics and probiotics on gastrointestinal and metabolic health. This Special Issue aims to summarize the current situation in this field and provide more references for future research.

For this Special Issue, we welcome all narrative and systematic reviews on any aspects (e.g., clinical, in vivo, in vitro), in order to report the effect of gut microbiota, pre- and probiotics, and their products, on human health and disease.

Dr. Lorella Paparo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • prebiotics
  • probiotics
  • parabiotics
  • gut microbiome
  • functional gastrointestinal disorders (FGIDs)
  • celiac disease
  • food allergies
  • chronic inflammation

Published Papers (3 papers)

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Review

14 pages, 686 KiB  
Review
Nutritional Strategies for the Prevention and Management of Cow’s Milk Allergy in the Pediatric Age
by Serena Coppola, Laura Carucci, Franca Oglio, Claudia Di Sarra, Gulsum Ozen and Roberto Berni Canani
Nutrients 2023, 15(15), 3328; https://doi.org/10.3390/nu15153328 - 26 Jul 2023
Cited by 1 | Viewed by 1658
Abstract
Cow’s milk allergy (CMA) is one of the most common pediatric food allergies. The prevalence and severity of CMA have increased dramatically in the last decades, under the pressure of environmental factors in genetically predisposed individuals. Among the environmental influences, nutritional factors play [...] Read more.
Cow’s milk allergy (CMA) is one of the most common pediatric food allergies. The prevalence and severity of CMA have increased dramatically in the last decades, under the pressure of environmental factors in genetically predisposed individuals. Among the environmental influences, nutritional factors play a crucial role. Diet is the most modifiable factor, representing a potential target for the prevention and treatment of CMA. In this review, we report the most scientific-based nutritional strategies for preventing and managing pediatric CMA. In addition, we propose the most complete supplement of compounds able to prevent nutrient deficiencies in CMA pediatric patients and to positively influence the disease course. Full article
(This article belongs to the Special Issue Featured Reviews on Prebiotics and Probiotics)
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28 pages, 1446 KiB  
Review
Prebiotic and Probiotic Modulation of the Microbiota–Gut–Brain Axis in Depression
by Daniel E. Radford-Smith and Daniel C. Anthony
Nutrients 2023, 15(8), 1880; https://doi.org/10.3390/nu15081880 - 13 Apr 2023
Cited by 10 | Viewed by 4930
Abstract
Emerging evidence demonstrates that alterations to the gut microbiota can affect mood, suggesting that the microbiota–gut–brain (MGB) axis contributes to the pathogenesis of depression. Many of these pathways overlap with the way in which the gut microbiota are thought to contribute to metabolic [...] Read more.
Emerging evidence demonstrates that alterations to the gut microbiota can affect mood, suggesting that the microbiota–gut–brain (MGB) axis contributes to the pathogenesis of depression. Many of these pathways overlap with the way in which the gut microbiota are thought to contribute to metabolic disease progression and obesity. In rodents, prebiotics and probiotics have been shown to modulate the composition and function of the gut microbiota. Together with germ-free rodent models, probiotics have provided compelling evidence for a causal relationship between microbes, microbial metabolites, and altered neurochemical signalling and inflammatory pathways in the brain. In humans, probiotic supplementation has demonstrated modest antidepressant effects in individuals with depressive symptoms, though more studies in clinically relevant populations are needed. This review critically discusses the role of the MGB axis in depression pathophysiology, integrating preclinical and clinical evidence, as well as the putative routes of communication between the microbiota–gut interface and the brain. A critical overview of the current approaches to investigating microbiome changes in depression is provided. To effectively translate preclinical breakthroughs in MGB axis research into novel therapies, rigorous placebo-controlled trials alongside a mechanistic and biochemical understanding of prebiotic and probiotic action are required from future research. Full article
(This article belongs to the Special Issue Featured Reviews on Prebiotics and Probiotics)
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14 pages, 318 KiB  
Review
The Role of Gluten in Gastrointestinal Disorders: A Review
by Sabrina Cenni, Veronica Sesenna, Giulia Boiardi, Marianna Casertano, Giuseppina Russo, Alfonso Reginelli, Susanna Esposito and Caterina Strisciuglio
Nutrients 2023, 15(7), 1615; https://doi.org/10.3390/nu15071615 - 27 Mar 2023
Cited by 4 | Viewed by 3612
Abstract
Gluten is only partially digested by intestinal enzymes and can generate peptides that can alter intestinal permeability, facilitating bacterial translocation, thus affecting the immune system. Few studies addressed the role of diet with gluten in the development of intestinal inflammation and in other [...] Read more.
Gluten is only partially digested by intestinal enzymes and can generate peptides that can alter intestinal permeability, facilitating bacterial translocation, thus affecting the immune system. Few studies addressed the role of diet with gluten in the development of intestinal inflammation and in other gastrointestinal disorders. The aim of this narrative review was to analyse the role of gluten in several gastrointestinal diseases so as to give a useful overview of its effectiveness in the prevention and management of these disorders. Full article
(This article belongs to the Special Issue Featured Reviews on Prebiotics and Probiotics)
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