Low-Calorie Sweeteners: Benefits and Risks in Human Health
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Carbohydrates".
Deadline for manuscript submissions: 5 May 2024 | Viewed by 7505
Special Issue Editors
Interests: low-calorie sweeteners; endocrinology; diabetes; obesity; nephrology; pharmacokinetics; pharmacodynamics
Special Issue Information
Dear Colleagues,
Selected low-calorie sweeteners (LCS) have been used for over 100 years to replace nutritive sweeteners such as sucrose with the goal of enabling calorie reduction, weight management, and possible improvement of several related metabolic consequences of overweight and obesity. While numerous worldwide regulatory bodies have approved many LCS as safe for human consumption, there remain controversies over possible negative outcomes from the use of these substances over time. For example, recent research suggests that aspartame and sucralose may alter the composition of the gut microbiome. Others have suggested that there may be negative cardiovascular outcomes from aspartame and acesulfame K. A fundamental issue that is often not addressed in both the epidemiologic research and consumer communities is that LCS with vastly different structures, metabolisms and physiological consequences are grouped together based solely on the fact that they have a sweet taste and few or zero calories. There are also newer compounds such as flavors with modifying properties (FMPs) that augment sweet taste and are less studied. This Special Issue seeks to highlight both the potential benefits and risks of the use of LCS in human health with particular emphasis on examining individual sweetener substitutes to avoid inferring class effects where none have yet been substantiated.
Dr. John St. Peter
Dr. Danielle Greenberg
Guest Editors
Manuscript Submission Information
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Keywords
- low-calorie sweeteners
- obesity
- gut microbiome
- weight management
- chronic disease
- sweetener systems
- sweet taste
- flavors with modifying properties (FMPs)
