Dietary Patterns and Cardiovascular Disease

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Metabolism".

Deadline for manuscript submissions: 15 July 2024 | Viewed by 1909

Special Issue Editor


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Guest Editor
Department of Family Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea
Interests: diet; obesity; CVD; genes; diabetes; metabolic disease; hypertension; dyslipidemia

Special Issue Information

Dear Colleagues,

Cardiovascular disease (CVD) is the leading cause of death worldwide, accounting for one third of all deaths worldwide. The impact of dietary patterns on the cardiometabolic pathway is crucial in understanding and addressing this health concern. CVD arises from a combination of genetic and environmental factors, with dietary patterns playing a pivotal role in the latter. Moreover, the influence of genetic risk for CVD may be alleviated or intensified based on individual dietary pattern. Balanced nutrition and well-organized dietary patterns provide great opportunities to reduce the risk of cardiovascular events. Although this field has advanced rapidly, it has also engendered confusion, and not all relevant information is certain. 

This Special Issue will aim to discuss the crucial link between nutrition and cardiovascular disease while focusing on overall diet pattern. It will also aim to investigate the interplay of various nutrients, as well as their impact on lipids and blood pressure, beyond the study of single isolated nutritional components. Additionally, we welcome related studies on public policies and practices aimed at alleviating the burdens of diet-related CVD.

Dr. Dong-Hyuk Jung
Guest Editor

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Keywords

  • cardiovascular disease
  • dietary pattern
  • nutrition
  • CVD risk factors
  • lipids
  • blood pressure
  • gene
  • epigenetics

Published Papers (2 papers)

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Research

13 pages, 926 KiB  
Article
Association of Dietary Patterns with Cardiovascular Disease Risk Factors in Mexican Adults: Insights from a Cross-Sectional Descriptive Study
by Alejandra Vázquez-Aguilar, Ascensión Rueda-Robles, Lorenzo Rivas-García, Héctor Vázquez-Lorente, Carmen María Duque-Soto, Karla Lizbet Jiménez-López, Isabel Cristina Marín-Arriola, Martha Alicia Sánchez-Jiménez and Patricia Josefina López-Uriarte
Nutrients 2024, 16(6), 804; https://doi.org/10.3390/nu16060804 - 12 Mar 2024
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Abstract
Dietary patterns (DPs) are an essential tool to analyze the relationship between diet and health as they have presented an association with the incidence of chronic non-communicable diseases. Therefore, the aim of this study was the identification and characterization of DPs and their [...] Read more.
Dietary patterns (DPs) are an essential tool to analyze the relationship between diet and health as they have presented an association with the incidence of chronic non-communicable diseases. Therefore, the aim of this study was the identification and characterization of DPs and their association with cardiovascular risk factors. For this purpose, a cross-sectional descriptive study was carried out in 165 Mexican adults, including dietary intakes derived from a validated food frequency questionnaire, clinical history, anthropometry, and biochemical biomarkers using standardized procedures for glucose, total cholesterol, triglycerides, LDL-c, and HDL-c. DPs were identified through principal component analysis and ordinal logistic regression was used to examine associations between DPs and cardiovascular disease risk factors. Three DPs were identified: Mexican Fast-Food, Variety-Food, and Healthy-Economic, with a high prevalence of overweight and obesity (78%). Having a high adherence to a Mexican Fast-Food pattern (OR 1.71 CI 1.4–2.8), being sedentary (OR 4.85 2.32–10.15) and smoking (0R 6.4 CI 2.40–16.9) increased the risk of having a high scale of risk factors (four or more risk factors simultaneously). In conclusion, the Mexican Fast-Food pattern showed an increase in the risk of having multiple risk factors, while a sedentary lifestyle and overeating were largely responsible for the prevalence of overweight and obesity in this group of Mexican adults. Full article
(This article belongs to the Special Issue Dietary Patterns and Cardiovascular Disease)
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12 pages, 1015 KiB  
Article
Genetic Variants Linked to Myocardial Infarction in Individuals with Non-Alcoholic Fatty Liver Disease and Their Potential Interaction with Dietary Patterns
by Sung-Bum Lee, Ja-Eun Choi, Kyung-Won Hong and Dong-Hyuk Jung
Nutrients 2024, 16(5), 602; https://doi.org/10.3390/nu16050602 - 22 Feb 2024
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Abstract
In recent studies, non-alcoholic fatty liver disease (NAFLD) has been associated with a high risk of ischemic heart disease. This study aimed to investigate a genetic variant within a specific gene associated with myocardial infarction (MI) among patients with NAFLD. We included 57,205 [...] Read more.
In recent studies, non-alcoholic fatty liver disease (NAFLD) has been associated with a high risk of ischemic heart disease. This study aimed to investigate a genetic variant within a specific gene associated with myocardial infarction (MI) among patients with NAFLD. We included 57,205 participants from a Korean genome and epidemiology study. The baseline population consisted of 45,400 individuals, with 11,805 identified as patients with NAFLD. Genome-wide association studies were conducted for three groups: the entire sample, the healthy population, and patients with NAFLD. We defined the p-value < 1 × 10−5 as the nominal significance and the p-value < 5 × 10−2 as statistically significant for the gene-by-nutrient interaction. Among the significant single-nucleotide polymorphisms (SNPs), the lead SNP of each locus was further analyzed. In this cross-sectional study, a total of 1529 participants (2.8%) had experienced MI. Multivariable logistic regression was performed to evaluate the association of 102 SNPs across nine loci. Nine SNPs (rs11891202, rs2278549, rs13146480, rs17293047, rs184257317, rs183081683, rs1887427, rs146939423, and rs76662689) demonstrated an association with MI in the group with NAFLD Notably, the MI-associated SNP, rs134146480, located within the SORCS2 gene, known for its role in secreting insulin in islet cells, showed the most significant association with MI (p-value = 2.55 × 10−7). Our study identifies candidate genetic polymorphisms associated with NAFLD-related MI. These findings may serve as valuable indicators for estimating MI risk and for conducting future investigations into the underlying mechanisms of NAFLD-related MI. Full article
(This article belongs to the Special Issue Dietary Patterns and Cardiovascular Disease)
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