Present and Future Perspectives on Next-Generation Sequencing Use within Current Assisted Reproductive Technologies
A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Obstetrics and Gynecology".
Deadline for manuscript submissions: closed (31 October 2022) | Viewed by 2851
Special Issue Editors
Interests: human reproduction preimplantational genetic testing and rare disease endometriosis minimal invasive surgery
Special Issues, Collections and Topics in MDPI journals
Interests: reproductive endocrinology; the genetics of male infertility; ovulation induction
Special Issue Information
Dear Colleagues,
There is currently an increasing trend and interest in the current literature regarding the fulminant ascension and crucial role of molecular biology that revolutionized not only the field of genomic research but also that of assisted reproductive technologies (ARTs) as well. More precisely, ART provides a plethora of advantages for many couples at the reproductive age that are struggling with infertility or other debilitating disorders. Based on this argument, next generation sequencing (NGS) has become an integrated component within the current protocols as in vitro fertilization (IVF) success depends on the quality of the embryo(s). Presently, NGS is gaining more and more attention due to its low costs; perspectives offered compared to previous methodologies and other newest advances; pre-implantation genetic screening (PGS) and high-resolution (hr-NGS) for chromosomal count and screening of the embryo(s); and establishment of the possible risk of inherited and/or de novo defects. Therefore, the purpose of the present Special Issue is to gather original research, review articles, and case reports focused on this topic in order to deepen our understanding. Additionally, contradictory and confirmatory results are welcome in terms of both human and animal models.
Dr. Bogdan Doroftei
Dr. Edgar V. Mocanu
Dr. Svetlana Rechitsky
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- assisted reproductive technology
- in vitro fertilization
- next generation sequencing
- pre-implantation genetic testing
- clinical pregnancy
- live birth
- infertility
- miscarriage
- maternal disease
- foetal abnormalities
