The Ketogenic Diet in the Management of Adult Neurological Disorders: Physiological Adaptation Mechanisms

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".

Deadline for manuscript submissions: 25 August 2024 | Viewed by 70

Special Issue Editors


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Guest Editor
Department of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo, Via del Vespro 129, 90127 Palermo, Italy
Interests: physiology of nutrition; controlled feeding studies; phytonutrients; relationships between dietary intake and physiological outcomes; malnourishment; metabolism; multiple sclerosis
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Biomedicine, Neuroscience and Advanced Diagnostics (BIND), University of Palermo, 90134 Palermo, Italy
Interests: cognitive neuroscience; spatial cognition; neurolinguistics; cortical excitability; motor cortex; computational models; brain stimulation; TMS; tDCS

Special Issue Information

Dear Colleagues,

The ketogenic diet has been re-evaluated in recent years and has been proposed as an effective nonfarmacological intervention in several neurological conditions such as Alzheimer's, Parkinson's, and Multiple Sclerosis. As conventional therapies that are used to treat neurological disorders are increasingly associated with drug resistance and drug tolerance, nutritional therapy is becoming a useful adjunct for improving disease progression. However, to date, the complex relationship between the effects of the ketogenic diet and the pathophysiological mechanisms of neurodegereative and autoinflammatory neurological diseases,  as well as its clinical relevance, is still lacking strong evidence. The purpose of this Special Issue to provide an insight into the mechanisms of neuromodulation and neuroprotection that develop when a ketogenic diet regimen is applied and that can be considered to be improving the management of neurological disorders. Both mechanicistics and clinical interventional works, as well as reviews, are welcome.  The Special Issue will also focus on the nutrition–microbiome and neuroprotection axis to take stock of the qualitative and quantitative aspects of the ketogenic diet that cannot be overlooked when evaluating beneficial neurological effects.

Dr. Danila Di Majo
Dr. Giuseppe Giglia
Guest Editors

Manuscript Submission Information

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Keywords

  • neurological disease
  • ketogenic diet
  • microbiome
  • neuromodulation
  • neuroprotection

Published Papers

This special issue is now open for submission.
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