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The Role of Phytochemicals in Neurological Disorders

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 20 April 2024 | Viewed by 525

Special Issue Editors

Laboratory of Food and Health, Food and Technology Department, National Council for Scientific Research (CEBAS-CSIC), Murcia, Spain
Interests: food and health; bioactive compounds; polyphenols; cell culture and animal models; clinical trials; cardiovascular; cancer; inflammation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Phytochemicals present in foods, spices and herbs, such as polyphenols, carotenoids and phytosterols, among others, constitute an unlimited source of molecules available for the prevention of numerous diseases and improving human health. Thousands of studies have already firmly established the intimate association between phytochemicals and their significantly neuroprotective activity in neurological disorders (i.e., dementia, cognitive decline, Alzheimer’s, Parkinson’s, stroke, ischemic injury, cancers, etc.), most of which are associated with gradual loss of neurons attributed to increased oxidative stress at the cellular level.

In recent years, bioactive phytochemicals have attracted enormous interest for their roles in preventive strategies (increasing the daily intake) and as adjuvants in the treatment of these pathologies (administered in co-treatment or present in pharmaceutical forms) owing to their potent antioxidant and anti-inflammatory activities. Food supplements containing phytochemicals are now widely used, and it seems that this market will tend to grow more and more in the coming years.

Led by Dr. Alessandro Attanzio, Dr. Antonio Cilla, Dr. Antonio González-Sarrías and our Topical Advisory Panel Member Dr. Ignazio Restivo (University of Palermo). For this Special Issue “The Role of Phytochemicals in Neurological Disorders”, we invite investigators to contribute with original research articles as well as review articles covering the biological effect of natural products in the prevention of neurodegeneration through comparisons between both relevant in vivo and in vitro models and with particular focus on biochemical signaling pathways.

Dr. Alessandro Attanzio
Dr. Antonio Cilla
Dr. Antonio González-Sarrías
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • phytochemicals
  • neurodegeneration
  • antioxidant activity
  • anti-inflammatory activity
  • nutrition
  • bioactive
  • inhibitor
  • functional foods
  • nutraceuticals
  • molecular mechanism

Published Papers

This special issue is now open for submission.
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