Hypothalamic Hormonal Secretion and Metabolism
Deadline for manuscript submissions: 15 June 2024 | Viewed by 3832
Interests: hypothalamic neuroinflammation; insulin resistance; microRNAs
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The central role of the hypothalamus in the control of several vital physiological functions is due to its ability to integrate numerous signals from the brain as well as the periphery and to deliver an adequate response. The hypothalamus plays a central role in the control of energy homeostasis, water balance, reproduction and sexual maturity, circadian rhythm and sleep, and stress. Indeed, the hypothalamic neurons project to the median eminence and secrete neurohormones into the portal blood linking the hypothalamus to the anterior pituitary gland, or directly to the posterior pituitary gland in the case of vasopressin or oxytocin. All of these secretions are regulated by feedback signals from the endocrine glands and other circulating factors (nutrients, hormones). Besides its role in hormonal secretion, the hypothalamus is able to integrate many signals from the periphery or higher brain centers to respond to body needs, such as, for instance, maintaining glucose homeostasis and controlling eating behavior.
The present topic will be dedicated to the role of the endocrine hypothalamus in the control of whole-body metabolism to allow fine regulation to achieve homeostasis.
Prof. Dr. Mohammed Taouis
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- endocrine control
- energy homeostasis