Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Mechanism of Protein Synthesis in Alzheimer's Disease
edited by Antonella Borreca
submission deadline 25 Apr 2024 | Viewed by 172 | Submission Open
Keywords: protein synthesis; UPR system; ER stress; translational factor and cognition; Alzheimer’ s disease; translational control; post-translational modification
(This special issue belongs to the Section Cells of the Nervous System)
Islet Transplantation
edited by Shinichi Matsumoto
submission deadline 26 Apr 2024 | 6 articles | Viewed by 7018 | Submission Open
Keywords: allogeneic islet transplantation; islet isolation; immunosuppression for islet transplantation; autologous islet transplantation; xenogeneic islet transplantation; transplantation site for islet transplantation; regenerative medicine for the treatment of diabetes
Cellular Regeneration Therapy for Traumatic Brain Injury (TBI)
edited by Xiang Gao
submission deadline 26 Apr 2024 | 2 articles | Viewed by 5463 | Submission Open
Keywords: traumatic brain injury; regenerative therapy; neural regeneration; genetic modification; stem-cell therapy; cell transplantation; in vivo iPS reprogramming
(This special issue belongs to the Section Cells of the Nervous System)
New Advances in Cellular Immunotherapy submission deadline 29 Apr 2024 | 2 articles | Viewed by 2649 | Submission Open
Keywords: adoptive cell therapy; immunotherapy; transplantation; immune evasions; tumor microenvironment; genetic editing; CAR T; TRUCK; NK
(This special issue belongs to the Section Cell and Gene Therapy)
Structures, Regulation, Signaling, and Physiological Functions of Adhesion G-Protein Coupled Receptors submission deadline 30 Apr 2024 | 9 articles | Viewed by 21339 | Submission Open
Keywords: adhesion GPCR; physiology; animal models; clinical studies; signaling; ligands; structures; computational
(This special issue belongs to the Section Cell Signaling)
Glial Scar: Formation and Regeneration submission deadline 30 Apr 2024 | 6 articles | Viewed by 14775 | Submission Open
Keywords: CNS; reactive gliosis; inflammation; scarring; tissue cytoarchitecture; neurorepair
(This special issue belongs to the Section Cells of the Nervous System)
The Molecular Mechanisms of Bile Acids in Diseases
edited by and
submission deadline 30 Apr 2024 | 6 articles | Viewed by 13057 | Submission Open
Role of Vascular Smooth Muscle Cells in Cardiovascular Disease
edited by and Claire Holden
submission deadline 30 Apr 2024 | 8 articles | Viewed by 11942 | Submission Open
Keywords: cardiovascular disease; vascular smooth muscle cell (VSMC); phenotypic modulation; VSMC migration; atherosclerosis; VSMC plasticity; vascular injury; foam cells; stroke; myocardial infarction; peripheral artery disease (PAD); restenosis; inflammation; metabolism
(This special issue belongs to the Section Cells of the Cardiovascular System)
Cell-Penetrating Peptides (CPPs) in Cancer: From Molecular Mechanisms to Applications in Diagnostic and Therapeutic Opportunities
edited by , and
submission deadline 30 Apr 2024 | 3 articles | Viewed by 9340 | Submission Open
Keywords: tumors; cellular internalization; targeting delivery; cargo molecule conjugations; tumor imaging; toxicity
(This special issue belongs to the Section Cellular Pathology)
Advances in Ubiquitination and Deubiquitination Research
edited by
submission deadline 30 Apr 2024 | 6 articles | Viewed by 8618 | Submission Open
Keywords: ubiquitin; ubiquitination; deubiquitination; ubiquitin-interacting protein; ubiquitin linkage
Apoptosis and Alternative Modes of Cell Death as Targets for Anticancer Therapy
edited by
submission deadline 30 Apr 2024 | 5 articles | Viewed by 7300 | Submission Open
Keywords: apoptosis; cancer therapy; cell death; autophagy; necroptosis; ferroptosis; pyroptosis; stem cells; small RNAs; extracellular vesicles; intercellular communication
(This special issue belongs to the Section Cellular Pathology)
Extracellular Vesicles—Roles in Metastasis and Mediation of Cellular Cross Talk
edited by
submission deadline 30 Apr 2024 | 2 articles | Viewed by 5874 | Submission Open
Keywords: extracellular vesicles; exosomes; metastasis; tumor microenvironment; tumor immune response; tumor-associated macrophages; cancer-associated fibroblasts; pro-metastatic; anti-metastatic
(This special issue belongs to the Section Cell Microenvironment)
New Insights into Endothelial Signaling: Inflammation, Infection and Immune Modulation
edited by
submission deadline 30 Apr 2024 | 4 articles | Viewed by 4875 | Submission Open
Keywords: vascular endothelium; inflammation; innate immunity; adaptive immunity; reactive oxygen species; pattern recognition receptors; immunomodulation
(This special issue belongs to the Section Cell Signaling)
Breakthroughs in Cell Signaling in Health and Disease submission deadline 30 Apr 2024 | 3 articles | Viewed by 4788 | Submission Open
Keywords: receptor; pathways; second messengers; human disease
(This special issue belongs to the Section Cell Signaling)
Multidrug Resistance In Vitro and in Clinics
edited by
submission deadline 30 Apr 2024 | 2 articles | Viewed by 4470 | Submission Open
Keywords: ABC transporters; molecular targets; cell death pathways; lysosomal drug sequestration; drug metabolism; tumor microenvironment
Diabetic Retinopathy: From Molecular Mechanisms to Therapeutic Opportunities submission deadline 30 Apr 2024 | 4 articles | Viewed by 4421 | Submission Open
Keywords: neurodegeneration; oxidative stress; inflammation; vasculopathy; nutraceuticals; drug delivery; retinal imaging; proteomics; metabolomics; gene therapy
(This special issue belongs to the Section Cellular Pathology)
Cytoskeletal Remodeling in Health and Disease submission deadline 30 Apr 2024 | 5 articles | Viewed by 4306 | Submission Open
Keywords: actin cytoskeleton; cellular mechanics; cancer; cytoskeletal proteins; immunity
(This special issue belongs to the Section Cell Motility and Adhesion)
Recent Research on the Role of Mitochondria in Neurodegeneration
edited by
submission deadline 30 Apr 2024 | 3 articles | Viewed by 4175 | Submission Open
Keywords: mitochondrial; neurodegeneration; metabolism; mitophagy; apoptosis
(This special issue belongs to the Section Cells of the Nervous System)
Glycoproteomics and Protein Glycosylation in Cell Biology and Diseases
edited by
submission deadline 30 Apr 2024 | 2 articles | Viewed by 4101 | Submission Open
Keywords: glycosylation  ; glycoproteomics  ; proteomics  ; mass spectrometry  ; glycobiology  ; glycan  ; glycomics  ; lectin
(This special issue belongs to the Section Cellular Metabolism)
The Role of Cilia in Health and Diseases
edited by Rim Hjeij
submission deadline 30 Apr 2024 | 3 articles | Viewed by 3887 | Submission Open
Keywords: motile cilia; motile ciliopathy; Primary ciliary dyskinesia; genetic screening; bronchiectasis; hydrocephalus; laterality defects; infertility; gene therapy
Role of Extracellular Vesicles in Inflammatory Diseases
edited by Lahiru Gangoda and Ishara Atukorala
submission deadline 30 Apr 2024 | 3 articles | Viewed by 3366 | Submission Open
Keywords: extracellular vesicles (EVs); inflammation; biomarkers; inflammatory diseases; cytokines
(This special issue belongs to the Section Cellular Immunology)
Cellular, Molecular and Multi-Omics Approaches for the Investigation of Human Neurodevelopmental Disorders submission deadline 30 Apr 2024 | 2 articles | Viewed by 2989 | Submission Open
Keywords: neurodevelopmental disorders; multi-omics technologies; molecular pathways; stem cell for disease modeling; regenerative medicine
(This special issue belongs to the Section Cells of the Nervous System)
Protein Modification and Mistranslation in Cells and Human Disease submission deadline 30 Apr 2024 | 1 articles | Viewed by 2415 | Submission Open
Keywords: acetylation; aminoacyl-tRNA syntheses; genetic code expansion; methylation; missense suppression; mistranslation; nonsense suppression; phosphorylation; posttranslational modification; protein synthesis; transfer RNA (tRNA); translation fidelity
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Inflammaging in Acute Kidney Injury (AKI) and Chronic Kidney Disease (CKD) submission deadline 30 Apr 2024 | 1 articles | Viewed by 2085 | Submission Open
(This special issue belongs to the Section Tissues and Organs)
The Current Applications and Potential of Human Pluripotent Stem Cells
edited by Leila Maouche-Chretien
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1929 | Submission Open
Keywords: human pluripotent stem cells; disease modeling; tissue engineering; organoids; regenerative medicine; epigenetic
(This special issue belongs to the Section Stem Cells)
Regulation of Iron Metabolism in Health and Disease submission deadline 30 Apr 2024 | 1 articles | Viewed by 1850 | Submission Open
Keywords: iron metabolism; oxidative stress; inflammation; ferroptosis; ferritinophagy; hepcidin; iron chelators; neurodegeneration; cardiovascular; cancer
(This special issue belongs to the Section Cellular Metabolism)
Polarization in Cell
edited by Keith E. Mostov
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1477 | Submission Open
Keywords: cell polarity; epithelial polarity; neuronal polarity; membrane traffic; apical surface; basolateral surface
(This special issue belongs to the Section Cellular Biophysics)
Senescent Cells: A Key to Understanding Aging and Age-Related Diseases
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1404 | Submission Open
Keywords: molecular genetics of ageing; biomarkers of cellular senescence; SASP; metabolism in old age; the role of mitochondria in the aging process; inflammaging; the aging brain; age-related diseases; diagnostic and therapeutic strategies targeting senescence in the clinic
Advanced Technology for Cellular Imaging
edited by Alessandro Grinzato, and
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1148 | Submission Open
Keywords: electron tomography; fluorescence microscopy; live cell imaging; multimodal imaging; super resolution microscopy; cell– cell interaction
Macrophage Activation and Regulation
edited by Subhankar Mukhopadhyay
submission deadline 30 Apr 2024 | 1 articles | Viewed by 986 | Submission Open
Keywords: macrophage activation; classical and alternative activation; M1 and M2 activation; inflammatory and regulatory cytokines; inflammatory and pro-resolution lipid mediators; immune activatory and inhibitory receptors; ITAM and ITIMs
(This special issue belongs to the Section Cellular Immunology)
Antiageing Developments: Past, Present and Future submission deadline 30 Apr 2024 | Viewed by 481 | Submission Open
Keywords: ageing; antiageing interventions; senolytic drugs; stem cells; gene editing; regenerative medicine; longevity medicine; nanomedicine; lifestyle interventions; gerontology
Hypoxia and Cancer: New Aspects 2.0
edited by Francesco Pezzella and
submission deadline 30 Apr 2024 | Viewed by 369 | Submission Open
Keywords: hypoxia; cancer; physiology
(This special issue belongs to the Section Cellular Pathology)
Recent Advancements in Mammalian Embryo Culture: From Animal Models to Humans submission deadline 30 Apr 2024 | Viewed by 274 | Submission Open
Keywords: preimplantation embryo development; oviduct; fallopian tube; uterus; endometrium; culture system; milli/microfluidics; morphokinetics; metabolomics; exosomes; embryo selection; aneuploidy
(This special issue belongs to the Section Reproductive Cells and Development)
Extracellular Vesicles as Modulators of Cancer Initiation, Progression and Therapy Resistance—Series II
edited by and Priya Samuel
submission deadline 30 Apr 2024 | Viewed by 239 | Submission Open
Keywords: extracellular vesicles; exosomes; microvesicles; tumor microenvironment; cancer drug resistance; cancer diagnosis; cancer prognosis; biomarkers; liquid biopsies; cancer therapy
(This special issue belongs to the Section Cellular Pathology)
Podocyte Pathophysiology
edited by
submission deadline 30 Apr 2024 | Viewed by 204 | Submission Open
Keywords: podocyte; podocytopathy; organoid; mitochondria; kidney therapy; actin cytoskeleton; integrity; glomerular basement membrane; extracellular matrix; intracellular trafficking; podocyte metabolism
(This special issue belongs to the Section Cellular Pathology)
The Dynamic Zebrafish Nervous System
edited by Su Guo
submission deadline 30 Apr 2024 | Viewed by 135 | Submission Open
Keywords: zebrafish; calcium imaging; mutant; neurons; microglia; astrocytes; in vivo; computational
Graft versus Host Disease (GVHD) after Hematopoietic Cell Transplantation
edited by Senthilnathan Palaniyandi
submission deadline 30 Apr 2024 | Viewed by 133 | Submission Open
Keywords: acute graft versus host disease; chronic graft versus host disease; hematopoietic cell transplantation; transplant immunology
(This special issue belongs to the Section Cellular Immunology)
Lipids, Lipoproteins and Lipid-Targeting Therapies in the Regulation of Immune Function and Inflammation submission deadline 30 Apr 2024 | Viewed by 123 | Submission Open
Keywords: lipids; lipoproteins; HDL; lipid-targeting therapies; immune function; immune cell activation and differentiation; immune inflammation; chronic disease; cardiometabolic disease; infectious disease; proteomics; lipidomics; lifestyle interventions; emerging methods
(This special issue belongs to the Section Cellular Immunology)
Vitamin D in Intestinal Health and Diseases
edited by Xiaolei Tang
submission deadline 30 Apr 2024 | Viewed by 115 | Submission Open
Keywords: vitamin D; intestines; microbiota; epithelial barrier; immune cells
Metabolomics and Proteomics in Chronic Obstructive Pulmonary Disease (COPD)
edited by Joaquim Gea Guiral
submission deadline 1 May 2024 | 2 articles | Viewed by 2535 | Submission Open
Keywords: COPD; phenotypes; metabolites; biomarkers; inflammation; energy production; protein catabolism; phospholipids; peptides
(This special issue belongs to the Section Cellular Metabolism)
Patterns across Developmental Scales submission deadline 10 May 2024 | Viewed by 289 | Submission Open
Keywords: patterning; organ; cells; differentiation; proliferation; death; biophysics
Molecular Insights: Bridging the Gap between Aging, Neurodegenerative Disease, and Cancer from Bench to Bedside
edited by
submission deadline 10 May 2024 | Viewed by 279 | Submission Open
Keywords: aging; neurodegeneration; cancer; cellular senescence; SASP; stem cell exhaustion; epigenetics; metabolism; mitochondria; proteostasis; inflammation; immune aging; DNA damage; genomic instability; cell cycle; proliferation; risk genes; biomarkers; therapeutics; disease models
Microglia in Neurological Diseases submission deadline 15 May 2024 | 6 articles | Viewed by 14844 | Submission Open
(This special issue belongs to the Section Cells of the Nervous System)
Stromal Cells—Structure, Function and Therapeutics Development
edited by Veronika Lukacs-Kornek
submission deadline 15 May 2024 | 5 articles | Viewed by 10211 | Submission Open
(This special issue belongs to the Section Cell and Gene Therapy)
Model Systems for Human Disease and Medicine: From Advanced Cell and Tissue Culture to In Silico Methods
edited by
submission deadline 15 May 2024 | 5 articles | Viewed by 7063 | Submission Open
Keywords: modelling; human model systems; in vitro; cells; stem cells; pluripotent stem cells; iPSC; tissue; organoid; organ-on-a-chip; cell-on-a-chip; in silico; disease; cancer; regenerative medicine; diagnostics; therapeutics
(This special issue belongs to the Section Cell Methods)
Model Systems and Candidate Genes for Inherited Cardiomyopathies submission deadline 15 May 2024 | 4 articles | Viewed by 6515 | Submission Open
Keywords: cardiovascular genetics; cardiomyopathy; animal model; RNA expression; microRNA
(This special issue belongs to the Section Cells of the Cardiovascular System)
Role of Inflammasome Activation in Innate and Adaptive Immunity submission deadline 15 May 2024 | 3 articles | Viewed by 4256 | Submission Open
Keywords: inflammasome; caspase-1; ASC specks; pyroptosis; innate immunity; adaptive immunity; sterile inflammation; cell death pathways; apoptosis; autophagy; NETosis; PANoptosis; ferroptosis; necroptosis; neurodegenerative disease; trauma; cerebral ischemia; biomarkers
(This special issue belongs to the Section Cellular Immunology)
Advances in Retinal Disease Treatments Based on Cell Therapy and Regenerative Medicine submission deadline 15 May 2024 | 1 articles | Viewed by 1039 | Submission Open
Keywords: retinal diseases; cell therapy; regenerative medicine; visual function restoration; tissue regeneration; neuronal survival; promising therapeutic strategies
Formation, Aggregation, Persistence, and Maturation of NETs
edited by , , and Maximilian Dölling
submission deadline 15 May 2024 | Viewed by 120 | Submission Open
Keywords: mechanisms of NET formation; NETs in diseases; degradation of NETs; NET therapeuticals; benefical NETs
(This special issue belongs to the Section Cellular Immunology)
Nucleic Acid Sensing in Respiratory Diseases—Series 2
edited by and Remo Russo
submission deadline 15 May 2024 | Viewed by 89 | Submission Open
Keywords: cGAS; STING; inflammasome; TLR; infection; cell stress; lung inflammation; inhibitors
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
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