Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cell Asymmetry and Polarity: Guiding Cellular Behavior and Development
edited by
submission deadline 19 Apr 2024 | Viewed by 199 | Submission Open
Keywords: cell asymmetry; cell polarity; tissue morphogenesis; planar cell polarity (PCP) pathway; wnt pathway; therapeutic implications
(This special issue belongs to the Section Cell Signaling)
The Role of the Obesity Paradox in Cancer Progression and Immunotherapy
edited by
submission deadline 20 Apr 2024 | 2 articles | Viewed by 3714 | Submission Open
Keywords: obesity paradox; tumor immunology; tumor metastasis; immunotherapy
(This special issue belongs to the Section Cell Microenvironment)
Advances in the Biogenesis, Biology, and Functions of Noncoding RNAs
edited by Xinguo Chen
submission deadline 20 Apr 2024 | 1 articles | Viewed by 929 | Submission Open
Keywords: noncoding RNA biogenesis; long noncoding RNA (lncRNAs); circular RNA (circRNAs); enhancer RNA (eRNAs); microRNA (miRNAs); PIWI-interacting RNAs (pi-RNAs); tRNA-derived fragments (tRFs)
Molecular Mechanism of Rectal Insulin Signalling in Inflammatory Bowel Disease
edited by
submission deadline 20 Apr 2024 | Viewed by 91 | Submission Open
Keywords: inflammatory bowel disease; insulin receptor; enteroendocrine cells; rectal insulin treatment; inflammation; microbiota; differentiation; local administration
Molecular Mechanism of Protein Synthesis in Alzheimer's Disease
edited by Antonella Borreca
submission deadline 25 Apr 2024 | Viewed by 165 | Submission Open
Keywords: protein synthesis; UPR system; ER stress; translational factor and cognition; Alzheimer’ s disease; translational control; post-translational modification
(This special issue belongs to the Section Cells of the Nervous System)
Islet Transplantation
edited by Shinichi Matsumoto
submission deadline 26 Apr 2024 | 6 articles | Viewed by 6847 | Submission Open
Keywords: allogeneic islet transplantation; islet isolation; immunosuppression for islet transplantation; autologous islet transplantation; xenogeneic islet transplantation; transplantation site for islet transplantation; regenerative medicine for the treatment of diabetes
Cellular Regeneration Therapy for Traumatic Brain Injury (TBI)
edited by Xiang Gao
submission deadline 26 Apr 2024 | 2 articles | Viewed by 5169 | Submission Open
Keywords: traumatic brain injury; regenerative therapy; neural regeneration; genetic modification; stem-cell therapy; cell transplantation; in vivo iPS reprogramming
(This special issue belongs to the Section Cells of the Nervous System)
New Advances in Cellular Immunotherapy submission deadline 29 Apr 2024 | 2 articles | Viewed by 2535 | Submission Open
Keywords: adoptive cell therapy; immunotherapy; transplantation; immune evasions; tumor microenvironment; genetic editing; CAR T; TRUCK; NK
(This special issue belongs to the Section Cell and Gene Therapy)
Structures, Regulation, Signaling, and Physiological Functions of Adhesion G-Protein Coupled Receptors submission deadline 30 Apr 2024 | 9 articles | Viewed by 21212 | Submission Open
Keywords: adhesion GPCR; physiology; animal models; clinical studies; signaling; ligands; structures; computational
(This special issue belongs to the Section Cell Signaling)
Oxidative Stress and Antioxidant Strategies: Relationships and Cellular Pathways for Human Health submission deadline 30 Apr 2024 | 9 articles | Viewed by 17440 | Submission Open
Keywords: oxidative stress; antioxidants; aging; human health and diseases
(This special issue belongs to the Section Cellular Pathology)
Glial Scar: Formation and Regeneration submission deadline 30 Apr 2024 | 6 articles | Viewed by 14555 | Submission Open
Keywords: CNS; reactive gliosis; inflammation; scarring; tissue cytoarchitecture; neurorepair
(This special issue belongs to the Section Cells of the Nervous System)
The Molecular Mechanisms of Bile Acids in Diseases
edited by and
submission deadline 30 Apr 2024 | 6 articles | Viewed by 12893 | Submission Open
Role of Vascular Smooth Muscle Cells in Cardiovascular Disease
edited by and Claire Holden
submission deadline 30 Apr 2024 | 8 articles | Viewed by 11552 | Submission Open
Keywords: cardiovascular disease; vascular smooth muscle cell (VSMC); phenotypic modulation; VSMC migration; atherosclerosis; VSMC plasticity; vascular injury; foam cells; stroke; myocardial infarction; peripheral artery disease (PAD); restenosis; inflammation; metabolism
(This special issue belongs to the Section Cells of the Cardiovascular System)
Cell-Penetrating Peptides (CPPs) in Cancer: From Molecular Mechanisms to Applications in Diagnostic and Therapeutic Opportunities
edited by , and
submission deadline 30 Apr 2024 | 3 articles | Viewed by 9262 | Submission Open
Keywords: tumors; cellular internalization; targeting delivery; cargo molecule conjugations; tumor imaging; toxicity
(This special issue belongs to the Section Cellular Pathology)
Advances in Ubiquitination and Deubiquitination Research
edited by
submission deadline 30 Apr 2024 | 5 articles | Viewed by 8338 | Submission Open
Keywords: ubiquitin; ubiquitination; deubiquitination; ubiquitin-interacting protein; ubiquitin linkage
Apoptosis and Alternative Modes of Cell Death as Targets for Anticancer Therapy
edited by
submission deadline 30 Apr 2024 | 5 articles | Viewed by 7177 | Submission Open
Keywords: apoptosis; cancer therapy; cell death; autophagy; necroptosis; ferroptosis; pyroptosis; stem cells; small RNAs; extracellular vesicles; intercellular communication
(This special issue belongs to the Section Cellular Pathology)
Extracellular Vesicles—Roles in Metastasis and Mediation of Cellular Cross Talk
edited by
submission deadline 30 Apr 2024 | 2 articles | Viewed by 5719 | Submission Open
Keywords: extracellular vesicles; exosomes; metastasis; tumor microenvironment; tumor immune response; tumor-associated macrophages; cancer-associated fibroblasts; pro-metastatic; anti-metastatic
(This special issue belongs to the Section Cell Microenvironment)
New Insights into Endothelial Signaling: Inflammation, Infection and Immune Modulation
edited by
submission deadline 30 Apr 2024 | 4 articles | Viewed by 4738 | Submission Open
Keywords: vascular endothelium; inflammation; innate immunity; adaptive immunity; reactive oxygen species; pattern recognition receptors; immunomodulation
(This special issue belongs to the Section Cell Signaling)
Breakthroughs in Cell Signaling in Health and Disease submission deadline 30 Apr 2024 | 3 articles | Viewed by 4683 | Submission Open
Keywords: receptor; pathways; second messengers; human disease
(This special issue belongs to the Section Cell Signaling)
Multidrug Resistance In Vitro and in Clinics
edited by
submission deadline 30 Apr 2024 | 2 articles | Viewed by 4436 | Submission Open
Keywords: ABC transporters; molecular targets; cell death pathways; lysosomal drug sequestration; drug metabolism; tumor microenvironment
Diabetic Retinopathy: From Molecular Mechanisms to Therapeutic Opportunities submission deadline 30 Apr 2024 | 4 articles | Viewed by 4348 | Submission Open
Keywords: neurodegeneration; oxidative stress; inflammation; vasculopathy; nutraceuticals; drug delivery; retinal imaging; proteomics; metabolomics; gene therapy
(This special issue belongs to the Section Cellular Pathology)
Recent Research on the Role of Mitochondria in Neurodegeneration
edited by
submission deadline 30 Apr 2024 | 3 articles | Viewed by 4124 | Submission Open
Keywords: mitochondrial; neurodegeneration; metabolism; mitophagy; apoptosis
(This special issue belongs to the Section Cells of the Nervous System)
Cytoskeletal Remodeling in Health and Disease submission deadline 30 Apr 2024 | 5 articles | Viewed by 4049 | Submission Open
Keywords: actin cytoskeleton; cellular mechanics; cancer; cytoskeletal proteins; immunity
(This special issue belongs to the Section Cell Motility and Adhesion)
Glycoproteomics and Protein Glycosylation in Cell Biology and Diseases
edited by
submission deadline 30 Apr 2024 | 2 articles | Viewed by 4041 | Submission Open
Keywords: glycosylation  ; glycoproteomics  ; proteomics  ; mass spectrometry  ; glycobiology  ; glycan  ; glycomics  ; lectin
(This special issue belongs to the Section Cellular Metabolism)
The Role of Cilia in Health and Diseases
edited by Rim Hjeij
submission deadline 30 Apr 2024 | 3 articles | Viewed by 3469 | Submission Open
Keywords: motile cilia; motile ciliopathy; Primary ciliary dyskinesia; genetic screening; bronchiectasis; hydrocephalus; laterality defects; infertility; gene therapy
Role of Extracellular Vesicles in Inflammatory Diseases
edited by Lahiru Gangoda and Ishara Atukorala
submission deadline 30 Apr 2024 | 3 articles | Viewed by 3257 | Submission Open
Keywords: extracellular vesicles (EVs); inflammation; biomarkers; inflammatory diseases; cytokines
(This special issue belongs to the Section Cellular Immunology)
Cellular, Molecular and Multi-Omics Approaches for the Investigation of Human Neurodevelopmental Disorders submission deadline 30 Apr 2024 | 2 articles | Viewed by 2948 | Submission Open
Keywords: neurodevelopmental disorders; multi-omics technologies; molecular pathways; stem cell for disease modeling; regenerative medicine
(This special issue belongs to the Section Cells of the Nervous System)
Protein Modification and Mistranslation in Cells and Human Disease submission deadline 30 Apr 2024 | 1 articles | Viewed by 2366 | Submission Open
Keywords: acetylation; aminoacyl-tRNA syntheses; genetic code expansion; methylation; missense suppression; mistranslation; nonsense suppression; phosphorylation; posttranslational modification; protein synthesis; transfer RNA (tRNA); translation fidelity
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Inflammaging in Acute Kidney Injury (AKI) and Chronic Kidney Disease (CKD) submission deadline 30 Apr 2024 | 1 articles | Viewed by 2065 | Submission Open
(This special issue belongs to the Section Tissues and Organs)
The Current Applications and Potential of Human Pluripotent Stem Cells
edited by Leila Maouche-Chretien
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1883 | Submission Open
Keywords: human pluripotent stem cells; disease modeling; tissue engineering; organoids; regenerative medicine; epigenetic
(This special issue belongs to the Section Stem Cells)
Regulation of Iron Metabolism in Health and Disease submission deadline 30 Apr 2024 | 1 articles | Viewed by 1825 | Submission Open
Keywords: iron metabolism; oxidative stress; inflammation; ferroptosis; ferritinophagy; hepcidin; iron chelators; neurodegeneration; cardiovascular; cancer
(This special issue belongs to the Section Cellular Metabolism)
Polarization in Cell
edited by Keith E. Mostov
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1443 | Submission Open
Keywords: cell polarity; epithelial polarity; neuronal polarity; membrane traffic; apical surface; basolateral surface
(This special issue belongs to the Section Cellular Biophysics)
Senescent Cells: A Key to Understanding Aging and Age-Related Diseases
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1334 | Submission Open
Keywords: molecular genetics of ageing; biomarkers of cellular senescence; SASP; metabolism in old age; the role of mitochondria in the aging process; inflammaging; the aging brain; age-related diseases; diagnostic and therapeutic strategies targeting senescence in the clinic
Advanced Technology for Cellular Imaging
edited by Alessandro Grinzato, and
submission deadline 30 Apr 2024 | 1 articles | Viewed by 1104 | Submission Open
Keywords: electron tomography; fluorescence microscopy; live cell imaging; multimodal imaging; super resolution microscopy; cell– cell interaction
Macrophage Activation and Regulation
edited by Subhankar Mukhopadhyay
submission deadline 30 Apr 2024 | 1 articles | Viewed by 949 | Submission Open
Keywords: macrophage activation; classical and alternative activation; M1 and M2 activation; inflammatory and regulatory cytokines; inflammatory and pro-resolution lipid mediators; immune activatory and inhibitory receptors; ITAM and ITIMs
(This special issue belongs to the Section Cellular Immunology)
Antiageing Developments: Past, Present and Future submission deadline 30 Apr 2024 | Viewed by 474 | Submission Open
Keywords: ageing; antiageing interventions; senolytic drugs; stem cells; gene editing; regenerative medicine; longevity medicine; nanomedicine; lifestyle interventions; gerontology
Hypoxia and Cancer: New Aspects 2.0
edited by Francesco Pezzella and
submission deadline 30 Apr 2024 | Viewed by 360 | Submission Open
Keywords: hypoxia; cancer; physiology
(This special issue belongs to the Section Cellular Pathology)
Recent Advancements in Mammalian Embryo Culture: From Animal Models to Humans submission deadline 30 Apr 2024 | Viewed by 262 | Submission Open
Keywords: preimplantation embryo development; oviduct; fallopian tube; uterus; endometrium; culture system; milli/microfluidics; morphokinetics; metabolomics; exosomes; embryo selection; aneuploidy
(This special issue belongs to the Section Reproductive Cells and Development)
Extracellular Vesicles as Modulators of Cancer Initiation, Progression and Therapy Resistance—Series II
edited by and Priya Samuel
submission deadline 30 Apr 2024 | Viewed by 236 | Submission Open
Keywords: extracellular vesicles; exosomes; microvesicles; tumor microenvironment; cancer drug resistance; cancer diagnosis; cancer prognosis; biomarkers; liquid biopsies; cancer therapy
(This special issue belongs to the Section Cellular Pathology)
The Research on Neuroscience in C. elegans
edited by , and Salvatore J. Cherra, III
submission deadline 30 Apr 2024 | Viewed by 230 | Submission Open
Keywords: new technology for neuroscience; neurodevelopment; synapse development; neuromuscular function; neurotoxicity; neuronal regeneration and degeneration; learning and memory; transgenerational memory; neuronal disorder modeling; communication between neuron and non-neuronal tissues; drug screening
(This special issue belongs to the Section Cells of the Nervous System)
Podocyte Pathophysiology
edited by
submission deadline 30 Apr 2024 | Viewed by 196 | Submission Open
Keywords: podocyte; podocytopathy; organoid; mitochondria; kidney therapy; actin cytoskeleton; integrity; glomerular basement membrane; extracellular matrix; intracellular trafficking; podocyte metabolism
(This special issue belongs to the Section Cellular Pathology)
Graft versus Host Disease (GVHD) after Hematopoietic Cell Transplantation
edited by Senthilnathan Palaniyandi
submission deadline 30 Apr 2024 | Viewed by 127 | Submission Open
Keywords: acute graft versus host disease; chronic graft versus host disease; hematopoietic cell transplantation; transplant immunology
(This special issue belongs to the Section Cellular Immunology)
The Dynamic Zebrafish Nervous System
edited by Su Guo
submission deadline 30 Apr 2024 | Viewed by 122 | Submission Open
Keywords: zebrafish; calcium imaging; mutant; neurons; microglia; astrocytes; in vivo; computational
Lipids, Lipoproteins and Lipid-Targeting Therapies in the Regulation of Immune Function and Inflammation submission deadline 30 Apr 2024 | Viewed by 114 | Submission Open
Keywords: lipids; lipoproteins; HDL; lipid-targeting therapies; immune function; immune cell activation and differentiation; immune inflammation; chronic disease; cardiometabolic disease; infectious disease; proteomics; lipidomics; lifestyle interventions; emerging methods
(This special issue belongs to the Section Cellular Immunology)
Molecular Insights into Systemic Lupus Erythematosus Pathogenesis: From Genes to Immune Signaling
edited by Shunichi Shiozawa
submission deadline 30 Apr 2024 | Viewed by 113 | Submission Open
Keywords: SLE; pathogenesis; cause; infectious; TCR revision
(This special issue belongs to the Section Cellular Pathology)
Vitamin D in Intestinal Health and Diseases
edited by Xiaolei Tang
submission deadline 30 Apr 2024 | Viewed by 109 | Submission Open
Keywords: vitamin D; intestines; microbiota; epithelial barrier; immune cells
Idiopathic Pulmonary Fibrosis: Pathogenic Pathways and Treatment Strategies submission deadline 1 May 2024 | 6 articles | Viewed by 12211 | Submission Open
Keywords: idiopathic pulmonary fibrosis; interstitial lung disease; nintedanib; pirfenidone; extracellular matrix; alveolar epithelial injury; bleomycin
(This special issue belongs to the Section Tissues and Organs)
Metabolomics and Proteomics in Chronic Obstructive Pulmonary Disease (COPD)
edited by Joaquim Gea Guiral
submission deadline 1 May 2024 | 2 articles | Viewed by 2453 | Submission Open
Keywords: COPD; phenotypes; metabolites; biomarkers; inflammation; energy production; protein catabolism; phospholipids; peptides
(This special issue belongs to the Section Cellular Metabolism)
Patterns across Developmental Scales submission deadline 10 May 2024 | Viewed by 281 | Submission Open
Keywords: patterning; organ; cells; differentiation; proliferation; death; biophysics
Molecular Insights: Bridging the Gap between Aging, Neurodegenerative Disease, and Cancer from Bench to Bedside
edited by
submission deadline 10 May 2024 | Viewed by 269 | Submission Open
Keywords: aging; neurodegeneration; cancer; cellular senescence; SASP; stem cell exhaustion; epigenetics; metabolism; mitochondria; proteostasis; inflammation; immune aging; DNA damage; genomic instability; cell cycle; proliferation; risk genes; biomarkers; therapeutics; disease models
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