Special Issue "10th Anniversary of Biomedicines—Recent Advances on Adipokines"
Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 25331
Interests: adipose tissue; obesity; sepsis; inflammatory bowel disease; chemerin
Special Issues, Collections and Topics in MDPI journals
Special Issue in International Journal of Molecular Sciences: Adipokines 2.0
Special Issue in International Journal of Molecular Sciences: Adipokines 3.0
Special Issue in Cancers: Chemerin Signaling in Cancer
Special Issue in Biomedicines: The Role of Chemerin in Human Disease
Special Issue in Biomedicines: Feature Reviews in Adipokines
Special Issue in Biomedicines: Recent Advances in Adipokines—2nd Edition
The year 2022 marks the 10th anniversary of Biomedicines, a peer-reviewed open access journal in the biomedical field. Thus far, Biomedicines has published more than 2700 papers from more than 17,000 authors. We appreciate each author, reviewer, and academic editor whose support has brought us to where we are today. To celebrate this significant milestone, we aim to publish a Special Issue entitled “10th Anniversary of Biomedicines—Recent Advances on Adipokines".
Adipose tissues are composed of different cells such as adipocytes, fibroblasts, and immune cells. Adipose tissue-produced soluble proteins are referred to as adipokines irrespective of their cellular source. White fat tissue is organized into different depots in the body. Subcutaneous and visceral adipose tissues are the best studied compartments. Adipose tissues are also localized around organs such as the heart and kidney. Perinodal fat regulates the immune response in the lymph nodes. Brown adipose tissue differs greatly from white fat and has its own set of secreted hormones—the so-called “brown adipokines”.
To date, more than 500 adipokines have been described and most, if not all of them, are associated with overweight/obesity. While levels of most adipokines are increased in obesity, others decline. Associations between adipokines and cardiovascular diseases, insulin resistance, different types of cancers, and many more diseases have been identified. Further research has focused on the role of these proteins in immune responses, autoimmune diseases, and as antimicrobial peptides.
Adipokine receptors are mostly not very well characterized. Cell type, tissue expression, and regulation by different metabolites and signalling pathways have to be studied in more detail. Adipokine receptor agonists/antagonists may finally become new therapeutic targets.
Dr. Christa Buechler
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- visceral obesity