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Special Issue "Innovative In Vitro/In Silico Approaches to Drug Permeation and Absorption: The Highway to Implement the 3Rs Principles in Drug Development"
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Pharmacokinetics and Pharmacodynamics".
Deadline for manuscript submissions: 30 June 2023 | Viewed by 11825
Special Issue Editor
Interests: physical-pharmacy; passive drug diffusion; permeability; poorly soluble drugs; nanocarriers; cyclodextrins
Special Issue Information
The 3Rs (Replacement, Reduction and Refinement) are the guiding principles for a more ethical use of animals in product testing and scientific research. These guiding principles were first spelled out as a firm legal requirement by the EU commission in the Directive 2010/63/EU on the protection of animals used for scientific purposes. Yet, 12 years on from its legal implementation, the number of animals used in pharmaceutical research has not declined. This fact does not only create a big ethical/sustainability issue, but it also raises the question: is this the correct approach to understanding complex biopharmaceutic phenomena such as drug permeation and adsorption? The answer is: probably not. This Special Issue serves to highlight and capture the contemporary progress in in vitro/in silico approaches for the reliable prediction of in vivo drug performance with special emphasis on enabling formulation testing.
Dr. Massimiliano Pio di Cagno
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- in vitro permeation
- mechanism-based approach
- physical pharmacy
- drug permeation
- drug absorption
- computer-aided drug design
- passive diffusion
- active transport
- enabling formulation