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Special Issue "Production of Recombinant Molecules in Algal Chloroplasts"
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Microbial Biotechnology".
Deadline for manuscript submissions: closed (30 April 2023) | Viewed by 9277
Special Issue Editor
Interests: algal biotechnology; synthetic biology; chloroplast genetic engineering; oral vaccines and anti-microbials; photosynthesis
Special Issues, Collections and Topics in MDPI journals
Special Issue in Microorganisms: The Emerging Role of Cyanobacteria in Green Biotechnology
Special Issue Information
There is a growing interest in the use of microalgae as cell factories for the light-driven synthesis of recombinant products. These include recombinant proteins and RNAs that have potential application in areas such as therapeutics, and novel metabolites and biopolymers that have bioactive properties or could serve as feedstocks for green technologies. Key to the successful synthesis of a recombinant molecule is the robust expression of the transgene(s) and the hyper-accumulation of the product within the cell. In this regard, the algal chloroplast represents an attractive sub-cellular target as it possesses a small genetically tractable genome, and is able to serve as a storage compartment for proteins, polymers and lipids. Furthermore, the GRAS status of key microalgal species makes possible the idea of whole cell therapeutics in which live or dried cells serve as bioencapsulation devices for oral delivery of bioactive compounds. Although the model species Chlamydomonas reinhardtii is the most developed platform for algal chloroplast transgenics, the technology is now spreading to other industrially relevant species. It is, therefore, timely to launch this Special Issue, and I invite original reports or review articles covering basic or applied topics in the field—for example, methodologies for genetic engineering of algal chloroplasts (using either chloroplast or nuclear transformation approaches), novel recombinants produced in the algal chloroplast, and new biotechnological applications of engineered strains.
Prof. Dr. Saul Purton
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- metabolic engineering
- recombinant product
- algal biotechnology