The Role of Mitochondria in Metabolic Health and Disease
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Cell Metabolism".
Deadline for manuscript submissions: closed (31 August 2022) | Viewed by 5452
Special Issue Editors
Interests: diabetes; metabolic syndrome; mitochondrial calcium uniporter; metabolism physiology; beta-cell physiology; calcium/phosphate regulation
Interests: insulin signaling; diabetes; cardiovascular disease; endothelium; heart
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Mitochondria play essential roles in bioenergetics, redox balance, metabolic flexibility, Ca2+ homeostasis, cell signaling, immunity, growth, development, and cell death. Accordingly, mitochondria are critical for providing resistance to cell stressors, diseases, and senescence. However, mitochondrial dysfunction is a common pathophysiologic process in various conditions, such as metabolic syndrome, neurodegenerative diseases, cardiovascular diseases, cancer, and age-related diseases. Accumulating evidence suggests that the restoration of mitochondrial functions, e.g., by improving mitochondrial metabolism and suppressing oxidative stress, could be a therapeutic target for chronic diseases, such as those listed above. However, the molecular mechanisms related to the pathogenic progression of mitochondrial dysfunction remain to be clearly identified.
This Special Issue is dedicated to recent advances in the role of mitochondria in physiologic regulation, pathophysiologic alterations, and the development of mitochondrially related therapeutic strategies against chronic metabolic diseases and age-related diseases. We will consider original research articles, concept papers, short communications, and reviews on all aspects of mitochondrial biology, pathophysiology, and clinical applications. We hope that this Special Issue will contribute to advancing this fascinating field.
Prof. Dr. Kyu-Sang Park
Prof. Dr. Jaetaek Kim
Prof. Dr. Chan Bae Park
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- mitochondrial metabolism
- mitochondrial morphodynamics
- mitochondrial biogenesis
- mitochondrial stress response and mitohormesis
- mitochondrial oxidative stress
- mitophagy and quality control
- mitochondrial gene expression
- mitochondrial dysfunction
- mitochondrial diseases
- metabolic syndrome
- neurodegenerative diseases
- cardiovascular disease
- mitochondrial pathophysiology
