Special Issue "2-[18F]-FDG PET/CT in Oncology: New Evidences and Future Perspectives"
Deadline for manuscript submissions: closed (15 August 2021) | Viewed by 10077
Interests: lymphoma; nuclear medicine; PET/CT; imaging
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Cancer is one of the leading causes of death worldwide. Accurate diagnosis, staging and restaging are essential for the optimal management and therapeutic choice for oncological patients.
In this scenario, the potential usefulness of 2-deoxy-2-[18F]-fluoro-D-glucose positron emission tomography/computed tomography (2-[18F]-FDG PET/CT) is well demonstrated in different oncological diseases and for different purposes (such as staging, treatment response evaluation, restaging). 18F-FDG is an analogue of glucose and provides valuable functional information based on the increased glucose uptake and glycolysis of cancer cells and depicts metabolic abnormalities before morphological alterations occur. PET/CT is a hybrid tool that allows the acquisition of both morphological and functional data in the same imaging helping in the definition of disease status. However, there are some limitations and areas of uncertainty, mainly regarding the lack of specificity of 18F-FDG uptake and the variable FDG-avidity of some cancers.
Nowadays other more specific radiotracers (like choline, PSMA, DOTA-peptides) and new scanners (PET/MRI) have been developed with promising evidence; however, the role of 2-[18F]-FDG PET/CT remains fundamental and widespread. Moreover, several areas of interest are yet to be widely investigated.
This Special Issue will highlight the role of 2-[18F]-FDG PET/CT for the study of oncological diseases. We encourage authors to submit both preclinical and clinical studies in the field. Clinical studies may include systematic reviews, retrospective studies, and prospective studies emphasizing the role and need of 2-[18F]-FDG PET/CT in oncology.
Dr. Domenico Albano
Prof. Francesco Bertagna
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- nuclear medicine