Cutting-Edge Topics in Joint Arthroplasties

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Orthopedics".

Deadline for manuscript submissions: closed (20 February 2024) | Viewed by 922

Special Issue Editors

Guglielmo da Saliceto Polichirurgico Hospital AUSL Piacenza, 29121 Piacenza, Italy
Interests: knee arthroplasty; hip arthroplasty; trauma
Dr. Fabrizio Quattrini
E-Mail Website
Guest Editor
Guglielmo da Saliceto Polichirurgico Hospital AUSL Piacenza, 29121 Piacenza, Italy
Interests: knee arthroplasty; hip arthroplasty; arthroscopy
Orthopedics and Traumatology Department, Guglielmo da Saliceto Hospital, 29121 Piacenza, Italy
Interests: orthopedics and traumatology; trauma; fractures; arthroplasty; arthroscopic; knee; hip; elbow
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Special Issue Information

Dear Colleagues, 

Nowadays, joint replacement is one of the most frequent orthopedic surgery procedures. The progressive aging of the population, combined with the increase in the functional demands of elderly subjects, will lead to more and more prosthetic replacement operations. The objectives to be achieved in all replacements are: to provide total or at least partial pain relief, to achieve good stability, and to permit a wide range of motion (ROM) with minimal wear. This field is constantly evolving in terms of prosthetic components, surgical techniques, and rehabilitation protocols. Every year, we witness the evolution of prosthetic components, with the use of new materials, different shapes, and best-performing instruments; surgical techniques also evolve and modernize according to the needs of the population. Finally, patients are increasingly demanding: they want to return to their normal activities as quickly as possible, the pain to be resolved, and to start walking again immediately; sometimes, they request the use of particular surgical techniques or surgical approaches.

This Special Issue welcomes original research and review papers with a focus on the recent advances in joint arthroplasties; we aim to present the state of the art of the most modern surgical techniques and most recent perioperative and rehabilitation protocols.

Dr. Corrado Ciatti
Dr. Fabrizio Quattrini
Prof. Dr. Pietro Maniscalco
Guest Editors

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Keywords

  • arthroplasty
  • knee
  • hip
  • shoulder
  • bearing
  • outcome
  • revision surgery

Published Papers (1 paper)

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Research

11 pages, 388 KiB  
Article
Topical Fibrin Sealant (Tisseel@) Does Not Provide a Synergic Blood-Conservation Effect with Tranexamic Acid in Total Knee Arthroplasty—A Prospective Randomized Controlled Trial
Medicina 2023, 59(12), 2078; https://doi.org/10.3390/medicina59122078 - 26 Nov 2023
Viewed by 732
Abstract
Background and Objectives: The efficacy of tranexamic acid (TXA) in reducing perioperative blood loss during total knee arthroplasty (TKA) is well established. However, the potential synergistic blood-conservation effect of topical fibrin sealant (Tisseel@) remains unclear. This study aims to assess the effectiveness [...] Read more.
Background and Objectives: The efficacy of tranexamic acid (TXA) in reducing perioperative blood loss during total knee arthroplasty (TKA) is well established. However, the potential synergistic blood-conservation effect of topical fibrin sealant (Tisseel@) remains unclear. This study aims to assess the effectiveness of the combination of Tisseel and TXA during TKA. Materials and Methods: A single-blinded, prospective, randomized controlled trial was conducted with 100 patients (100 knees) undergoing primary TKA. Participants were randomly assigned to either the TXA group (n = 50), receiving intravenous (IV) TXA, or the Tisseel@ + TXA group (n = 50), receiving intra-articular Tisseel@ combined with IV TXA. The primary outcomes included blood transfusion rate, decrease in Hb level, calculated blood loss, and estimated total postoperative blood loss. Secondary outcomes involved assessing clinical differences between the groups. Results: The transfusion rate was zero in both groups. The average estimated blood loss in the Tisseel@ + TXA group was 0.463 ± 0.2422 L, which was similar to that of the TXA group at 0.455 ± 0.2522 L. The total calculated blood loss in the Tisseel@ + TXA group was 0.259 ± 0.1 L, compared with the TXA group’s 0.268 ± 0.108 L. The mean hemoglobin reduction in the first 24 h postoperatively was 1.57 ± 0.83 g/dL for the Tisseel@ + TXA group and 1.46 ± 0.82 g/dL for the TXA-only group. The reduction in blood loss in the topical Tisseel@ + TXA group was not significantly different from that achieved in the TXA-only group. The clinical results of TKA up to the 6-week follow-up were comparable between the groups. Conclusions: The combination of the topical fibrin sealant Tisseel@ and perioperative IV TXA administration, following the described protocol, demonstrated no significant synergistic blood-conservation effect in patients undergoing TKR. Full article
(This article belongs to the Special Issue Cutting-Edge Topics in Joint Arthroplasties)
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