New Insights into Heart Failure

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 1086

Special Issue Editors


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Guest Editor
1. Discipline of Internal Medicine and Ambulatory Care, Prevention and Cardiovascular Recovery, Department of Cardiology, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, Romania
2. Research Centre of Timisoara Institute of Cardiovascular Diseases, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, Romania
Interests: cardiovascular disease; atrial fibrillation; heart failure; stroke; coronary artery disease; cardiomyopathy; physical exercise or training; quality of life; anticoagulation; cardiac rehabilitation; primary and secondary prevention; valvular heart diseases; congenital heart disease; cardio genetics; clinical cardiology

E-Mail Website
Guest Editor
1. Discipline of Internal Medicine and Ambulatory Care, Prevention and Cardiovascular Recovery, Department of Cardiology, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, Romania
2. Research Centre of Timisoara Institute of Cardiovascular Diseases, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, Romania
Interests: cardiovascular disease; atrial fibrillation; heart failure; stroke; coronary artery disease; cardiomyopathy; physical exercise or training; quality of life; anticoagulation; cardiac rehabilitation; primary and secondary prevention; valvular heart diseases; congenital heart disease; cardio genetics; clinical cardiology

Special Issue Information

Dear Colleagues,

The Special Issue on “New Insights into Heart Failure” seeks to address the advancements in the diagnosis, treatment, and prevention of heart failure (HF).

HF is a clinical syndrome associated with increased morbidity, mortality, and healthcare costs. Heart failure affects about 26 million people worldwide, with more than 960,000 new cases each year. Left ventricular (LV) failure causes shortness of breath and fatigue, and right ventricular (RV) failure causes peripheral and abdominal fluid accumulation, but the ventricles can be involved together or separately. A wide variety of coexisting pathologies, diseases, or conditions can be found in HF patients, both cardiovascular and non-cardiovascular in nature, exhibiting diverse clinical relevance. The complex inter-relationship of comorbidities and their impact on the cardiovascular system contribute to the features of HF, both with reduced (HFrEF) and preserved ejection fraction (HFpEF). Hence, it can be stated that the coexisting morbidities help us determine the different phenotypes and consequences of HF. Understanding the pathogenesis and its complex associations with comorbidities can play a pivotal role in the prevention and treatment of HF.

This Special Issue invites contributions from researchers, clinicians, and experts in the field to explore the diverse challenges associated with heart failure, encompassing aspects such as etiology, diagnosis, treatment modalities, and patient care.

This Special Issue is now open for submissions (including original research articles, review papers, and case presentations) from clinicians and researchers in cardiovascular medicine and as well as researchers and clinicians specializing in different areas (i.e. metabolic diseases, pneumology, hematology, intensive care medicine, rheumatology, endocrinology, nephrology, internal medicine, family doctors, etc.).

Dr. Nilima Rajpal Kundnani
Prof. Dr. Simona Dragan
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • heart failure
  • risk factors
  • treatment
  • device therapy
  • biomarkers
  • aging
  • cardiovascular disease
  • coronary artery disease
  • valvular heart disease
  • arrythmias
  • stroke
  • COPD
  • cancers
  • liver cirrhosis

Published Papers (1 paper)

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Review

20 pages, 4310 KiB  
Review
Genotype-Phenotype Insights of Inherited Cardiomyopathies—A Review
by Oana Raluca Voinescu, Adina Ionac, Raluca Sosdean, Ioana Ionac, Luca Silvia Ana, Nilima Rajpal Kundnani, Stelian Morariu, Maria Puiu and Adela Chirita-Emandi
Medicina 2024, 60(4), 543; https://doi.org/10.3390/medicina60040543 - 27 Mar 2024
Viewed by 767
Abstract
Background: Cardiomyopathies (CMs) represent a heterogeneous group of primary myocardial diseases characterized by structural and functional abnormalities. They represent one of the leading causes of cardiac transplantations and cardiac death in young individuals. Clinically they vary from asymptomatic to symptomatic heart failure, [...] Read more.
Background: Cardiomyopathies (CMs) represent a heterogeneous group of primary myocardial diseases characterized by structural and functional abnormalities. They represent one of the leading causes of cardiac transplantations and cardiac death in young individuals. Clinically they vary from asymptomatic to symptomatic heart failure, with a high risk of sudden cardiac death due to malignant arrhythmias. With the increasing availability of genetic testing, a significant number of affected people are found to have an underlying genetic etiology. However, the awareness of the benefits of incorporating genetic test results into the care of these patients is relatively low. Aim: The focus of this review is to summarize the current basis of genetic CMs, including the most encountered genes associated with the main types of cardiomyopathies: hypertrophic, dilated, restrictive arrhythmogenic, and non-compaction. Materials and Methods: For this narrative review, we performed a search of multiple electronic databases, to select and evaluate relevant manuscripts. Results: Advances in genetic diagnosis led to better diagnosis precision and prognosis prediction, especially with regard to the risk of developing arrhythmias in certain subtypes of cardiomyopathies. Conclusions: Implementing the genomic information to benefit future patient care, better risk stratification and management, promises a better future for genotype-based treatment. Full article
(This article belongs to the Special Issue New Insights into Heart Failure)
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