Pitfalls and Challenges in Allergy Management

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Hematology and Immunology".

Deadline for manuscript submissions: 15 August 2024 | Viewed by 4486

Special Issue Editors


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Guest Editor
Department of Immunology and Allergy, Medical University of Lodz, Lodz, Poland
Interests: asthma; exercise-induced bronchoconstriction; allergic rhinitis; food allergy; urticaria and angioedema; molecular allergy diagnostics; biological treatment
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Internal Diseases, Allergology and Clinical Immunology, Medical University of Silesia, Katowice, Poland
Interests: allergic diseases; airway obstruction; asthma inflammation; lung diseases; food allergy and hypersensitivity; asthma management exercise-induced allergy syndromes; anaphylaxis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Every allergist in his or her practice has at least once been confronted with a situation when an apparently obvious and easy case turns into a puzzling challenge. A discrepancy between a patient’s history and laboratory IgE results, a lack of efficiency or unusual side effects of the therapy, and an unusual and atypical manifestation of allergic disease (or vice verca) can help to address the question of whether an allergy or asthma mask other conditions.

In the Special Issue of “Medicina”, which is now seeking submissions, you may find the perfect platform to share your clinical experience and theoretical knowledge with the international community of allergists and immunologists.

We strongly encourage you to submit and share case reports, case series, review papers, and orignal papers

describing clinical situations and topics that sometimes bring substantial doubts and difficulties to our daily routine.

This new Special Issue of “Medicina” provides a perfect opportunity for sharing your expertise and knowledge on this topic.

Dr. Marcin Kurowski
Prof. Dr. Radosław Gawlik
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • allergy
  • asthma
  • rhinitis
  • signs and symptoms
  • diagnostic difficulties
  • response to treatment

Published Papers (2 papers)

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Review

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10 pages, 917 KiB  
Review
Challenges in Local Allergic Rhinitis Diagnosis, Management, and Research: Current Concepts and Future Perspectives
by Mohamad Mahdi Mortada and Marcin Kurowski
Medicina 2023, 59(5), 929; https://doi.org/10.3390/medicina59050929 - 11 May 2023
Cited by 3 | Viewed by 2602
Abstract
Local allergic rhinitis (LAR) is diagnosed based on the presence of clinical symptoms such as rhinorrhea, sneezing, and nasal itching using negative skin prick testing and serum IgE assessment. Several novel studies have shown that it is possible to use the assessment of [...] Read more.
Local allergic rhinitis (LAR) is diagnosed based on the presence of clinical symptoms such as rhinorrhea, sneezing, and nasal itching using negative skin prick testing and serum IgE assessment. Several novel studies have shown that it is possible to use the assessment of nasal sIgE (specific immunoglobulin E) secretion as an additional diagnostic criterion for local allergic rhinitis. Additionally, allergen immunotherapy is a promising—albeit still not fully assessed and evaluated—future method of managing patients with LAR. In this review, the historical background, epidemiology, and main pathophysiological mechanisms of LAR shall be presented. Additionally, we address the current state of knowledge based on selected articles regarding the assessment of the local mucosal IgE presence in response to exposure to such allergens as mites, pollen, molds, and others. The impact of LAR on quality of life as well as the possible options of management (including allergen immunotherapy (AIT), which showed promising results) will then be presented. Full article
(This article belongs to the Special Issue Pitfalls and Challenges in Allergy Management)
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6 pages, 267 KiB  
Case Report
Ciprofloxacin-Induced Anaphylactic Reaction Followed by Negative Provocation Test in Response to Levofloxacin: A Case Report
by Marija Kurtov, Paula Kilić, Lucija Ikić, Karlo Kurtov, Gordan Dorčić, Marko Vodanović, Marinko Artuković and Marina Ikić Matijašević
Medicina 2023, 59(10), 1784; https://doi.org/10.3390/medicina59101784 - 07 Oct 2023
Cited by 2 | Viewed by 1436
Abstract
Fluoroquinolones are a commonly prescribed class of antibiotics due to their broad spectrum of antimicrobial activity, favorable pharmacokinetic properties, ability to switch from parenteral to oral administration, and global availability. After beta-lactams, they are the second most common antibiotic class associated with drug [...] Read more.
Fluoroquinolones are a commonly prescribed class of antibiotics due to their broad spectrum of antimicrobial activity, favorable pharmacokinetic properties, ability to switch from parenteral to oral administration, and global availability. After beta-lactams, they are the second most common antibiotic class associated with drug allergies. The mechanism of fluoroquinolone-induced hypersensitivity reactions has not yet been fully understood, so the true incidence of hypersensitivity reactions remains unknown. Cross-reactivity between fluoroquinolones has been the subject of conflicting and limited clinical research. Due to their similar chemical structure, some argue for close cross-reactivity within the group. However, recent studies have produced contradictory results. We present the case of a young patient who had an anaphylactic reaction to ciprofloxacin but was tolerant to levofloxacin, as determined via a skin prick test followed by a drug provocation test. Our findings support the notion that there is little cross-reactivity between fluoroquinolones. Consequently, exposure to another fluoroquinolone in a hospital setting may be beneficial, particularly for patients who lack adequate antibiotic alternatives. However, additional research on this subject is required. Full article
(This article belongs to the Special Issue Pitfalls and Challenges in Allergy Management)
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