Dear Colleagues,

Delving into the complexities of musculoskeletal diseases, the exploration of novel biomarkers takes center stage, uniting us in our common quest to advance medical knowledge and improve patient care. Together, we navigate the intricacies of this multifaceted field, pooling our collective expertise to uncover the hidden gems within our cells and tissues. As we delve deeper into genomics, proteomics, metabolomics, and beyond, our collaborative efforts shed light on the molecular intricacies that underlie musculoskeletal conditions. It is within these collaborative endeavors that we identify distinctive biomarkers, each a piece of the puzzle, enabling early diagnosis, personalized treatment, and precise disease monitoring.

This Special Issue will showcase research articles and review papers centered on biomarkers. We welcome contributions from researchers, clinicians, and data scientists who are keen to present their original work, with a particular emphasis on pioneering biomarkers related to musculoskeletal disorders. This field includes diagnostic biomarkers of osteoarthritis, developmental dysplasia of the hip, rheumatoid arthritis, psoriatic arthritis, juvenile idiopathic arthritis, gout, osteoporosis, osteopenia, muscular dystrophy, fibromyalgia, polymyalgia rheumatica, lupus, or biomarkers of cartilage degeneration in traumatic joint injuries and many others.

Topics concerning these biomarkers belong to, e.g.:

• Non-coding RNA molecules;
• Genetic and epigenetic biomarkers;
• Proteomic analyses;
• Metabolomic profiling;
• Extracellular vesicles;
• Predictive biomarker discovery;
• Imaging biomarkers;
• Inflammatory cytokines and chemokines;
• The microbiome;
• Multi-omics integration.

In this Special Issue, we invite our colleagues on this journey, where we find ourselves united by a shared commitment to pioneering research, innovative discovery, and the prospect of a healthier future for our patients. Together, we will illuminate the path forward and strive to find a better tomorrow.

Dr. Radoslav Zamborský
Dr. Štefan Harsányi
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• musculoskeletal diseases
• biomarkers
• osteoarthritis
• cartilage degeneration
• traumatic joint injuries
• juvenile idiopathic